ICD-10 Diagnosis Code N25.1

Nephrogenic diabetes insipidus

Diagnosis Code N25.1

ICD-10: N25.1
Short Description: Nephrogenic diabetes insipidus
Long Description: Nephrogenic diabetes insipidus
This is the 2018 version of the ICD-10-CM diagnosis code N25.1

Valid for Submission
The code N25.1 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Diseases of the genitourinary system (N00–N99)
    • Other disorders of kidney and ureter (N25-N29)
      • Disorders resulting from impaired renal tubular function (N25)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code N25.1 is grouped in the following Diagnostic Related Group(s) (MS-DRG V35.0)


Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.
  • 588.1 - Nephrogen diabetes insip

  • Acquired nephrogenic diabetes insipidus
  • Acquired nephrogenic diabetes insipidus
  • Drug-induced nephrogenic diabetes insipidus
  • Familial diabetes insipidus
  • Hereditary nephrogenic diabetes insipidus
  • Nephrogenic diabetes insipidus
  • Nephrogenic diabetes insipidus
  • Partial nephrogenic diabetes insipidus

Index of Diseases and Injuries
References found for the code N25.1 in the Index of Diseases and Injuries:

Information for Patients

Diabetes Insipidus

Also called: DI

Diabetes insipidus (DI) causes frequent urination. You become extremely thirsty, so you drink. Then you urinate. This cycle can keep you from sleeping or even make you wet the bed. Your body produces lots of urine that is almost all water.

DI is different from diabetes mellitus (DM), which involves insulin problems and high blood sugar. The symptoms can be similar. However, DI is related to how your kidneys handle fluids. It's much less common than DM. Urine and blood tests can show which one you have.

Usually, DI is caused by a problem with your pituitary gland or your kidneys. Treatment depends on the cause of the problem. Medicines can often help.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

  • Diabetes insipidus (Medical Encyclopedia)
  • Diabetes insipidus - central (Medical Encyclopedia)
  • Diabetes insipidus - nephrogenic (Medical Encyclopedia)

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Nephrogenic diabetes insipidus Nephrogenic diabetes insipidus is a disorder of water balance. The body normally balances fluid intake with the excretion of fluid in urine. However, people with nephrogenic diabetes insipidus produce too much urine (polyuria), which causes them to be excessively thirsty (polydipsia). Affected individuals can quickly become dehydrated if they do not drink enough water, especially in hot weather or when they are sick.Nephrogenic diabetes insipidus can be either acquired or hereditary. The acquired form is brought on by certain drugs and chronic diseases and can occur at any time during life. The hereditary form is caused by genetic mutations, and its signs and symptoms usually become apparent within the first few months of life.Infants with hereditary nephrogenic diabetes insipidus may eat poorly and fail to gain weight and grow at the expected rate (failure to thrive). They may also be irritable and experience fevers, diarrhea, and vomiting. Recurrent episodes of dehydration can lead to slow growth and delayed development. If the condition is not well-managed, over time it can damage the bladder and kidneys leading to pain, infections, and kidney failure. With appropriate treatment, affected individuals usually have few complications and a normal lifespan.Nephrogenic diabetes insipidus should not be confused with diabetes mellitus, which is much more common. Diabetes mellitus is characterized by high blood sugar levels resulting from a shortage of the hormone insulin or an insensitivity to this hormone. Although nephrogenic diabetes insipidus and diabetes mellitus have some features in common, they are separate disorders with different causes.
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