2024 ICD-10-CM Diagnosis Code K12.31

Oral mucositis (ulcerative) due to antineoplastic therapy

ICD-10-CM Code:
K12.31
ICD-10 Code for:
Oral mucositis (ulcerative) due to antineoplastic therapy
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Chronic
Code Navigator:

Code Classification

  • Diseases of the digestive system
    (K00–K95)
    • Diseases of oral cavity and salivary glands
      (K00-K14)
      • Stomatitis and related lesions
        (K12)

K12.31 is a billable diagnosis code used to specify a medical diagnosis of oral mucositis (ulcerative) due to antineoplastic therapy. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Inflammation of mucous membrane due to and following chemotherapy
  • Mucositis following radiation therapy
  • Stomatitis due to cytotoxic therapy
  • Stomatitis medicamentosa
  • Stomatitis medicamentosa
  • Ulcerative inflammation of oral mucous membrane due to and following administration of antineoplastic agent
  • Ulcerative mucositis due to non-antineoplastic therapy
  • Ulcerative stomatitis

Clinical Classification

Clinical CategoryCCSR Category CodeInpatient Default CCSROutpatient Default CCSR
Any dental condition including traumatic injuryDEN001N - Not default inpatient assignment for principal diagnosis or first-listed diagnosis.N - Not default outpatient assignment for principal diagnosis or first-listed diagnosis.
Conditions due to neoplasm or the treatment of neoplasmNEO074Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Diseases of mouth; excluding dentalDIG003N - Not default inpatient assignment for principal diagnosis or first-listed diagnosis.N - Not default outpatient assignment for principal diagnosis or first-listed diagnosis.
Nontraumatic dental conditionsDEN002N - Not default inpatient assignment for principal diagnosis or first-listed diagnosis.N - Not default outpatient assignment for principal diagnosis or first-listed diagnosis.

Clinical Information

  • Tumor Protein 63|CUSP|Chronic Ulcerative Stomatitis Protein|Keratinocyte Transcription Factor KET|TP63|Transformation-Related Protein 63|Tumor Protein p73-Like|p40|p51|p63|p73L

    tumor protein 63 (680 aa, ~77 kda) is encoded by the human tp63 gene. this protein plays a role in the mediation of both transcription and limb morphogenesis.
  • Ulcerative Stomatitis

    inflammation of the mouth mucosa associated with the presence of ulcers.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Use Additional Code

Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
  • code for adverse effect, if applicable, to identify antineoplastic and immunosuppressive drugs T45.1X5

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert K12.31 to ICD-9-CM

  • ICD-9-CM Code: 528.01 - Mucosits d/t antineo rx
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education


Cancer Chemotherapy

What is cancer chemotherapy?

Cancer chemotherapy is a type of cancer treatment. It uses medicines to destroy cancer cells.

Normally, the cells in your body grow and die in a controlled way. Cancer cells keep growing without control. Chemotherapy works by killing the cancer cells, stopping them from spreading, or slowing their growth.

Chemotherapy is used to:

  • Treat cancer by curing the cancer, lessening the chance it will return, or stopping or slowing its growth.
  • Ease cancer symptoms by shrinking tumors that are causing pain and other problems.

What are the side effects of chemotherapy?

Chemotherapy does not just destroy cancer cells. It can also harm some healthy cells, which causes side effects.

You may have a lot of side effects, some side effects, or none at all. It depends on the type and amount of chemotherapy you get and how your body reacts.

Some common side effects are:

  • Mouth sores
  • Fatigue
  • Nausea and vomiting
  • Pain
  • Hair loss

There are ways to prevent or control some side effects. Talk with your health care provider about how to manage them. Healthy cells usually recover after chemotherapy is over, so most side effects gradually go away.

What can I expect when getting chemotherapy?

You may get chemotherapy in a hospital or at home, a doctor's office, or a medical clinic. You might be given the medicines by mouth, in a shot, as a cream, through a catheter, or intravenously (by IV).

Your treatment plan will depend on the type of cancer you have, which chemotherapy medicines are used, the treatment goals, and how your body responds to the medicines.

Chemotherapy may be given alone or with other treatments. You may get treatment every day, every week, or every month. You may have breaks between treatments so that your body has a chance to build new healthy cells.

NIH: National Cancer Institute


[Learn More in MedlinePlus]

Oral Complications of Chemotherapy and Head/Neck Radiation (PDQ®)

Learn about oral complications of chemotherapy and head/neck radiation in adults and children, including preventing and managing problems such as mucositis, dry mouth, taste changes, pain, and infection.
[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.