2021 ICD-10-CM Codes for Sickle-cell disorders (D57)

Clinical Terms for Sickle-cell disorders (D57)

Sickle Cell Disorders-. A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.

Hemoglobin SC Disease-. One of the sickle cell disorders characterized by the presence of both hemoglobin S and hemoglobin C. It is similar to, but less severe than sickle cell anemia.

Sickle Cell Trait-. The condition of being heterozygous for hemoglobin S.

Instructional Notations

Use Additional Code Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.

  • code for any associated fever R50.81

Type 1 Excludes Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

  • other hemoglobinopathies D58
    • ICD-10 Index

      • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)

        • Hemolytic anemias (D55-D59)

            • Sickle-cell disorders (D57)
            • D57 - Sickle-cell disorders NON-BILLABLE CODE
            • D57.0 - Hb-SS disease with crisis NON-BILLABLE CODE
            • D57.00 - Hb-SS disease with crisis, unspecified BILLABLE CODE
            • D57.01 - Hb-SS disease with acute chest syndrome BILLABLE CODE
            • D57.02 - Hb-SS disease with splenic sequestration BILLABLE CODE
            • D57.03 - Hb-SS disease with cerebral vascular involvement BILLABLE CODE NEW CODE
            • D57.09 - Hb-SS disease with crisis with other specified complication BILLABLE CODE NEW CODE
            • D57.1 - Sickle-cell disease without crisis BILLABLE CODE
            • D57.2 - Sickle-cell/Hb-C disease NON-BILLABLE CODE
            • D57.20 - Sickle-cell/Hb-C disease without crisis BILLABLE CODE
            • D57.21 - Sickle-cell/Hb-C disease with crisis NON-BILLABLE CODE
            • D57.211 - Sickle-cell/Hb-C disease with acute chest syndrome BILLABLE CODE
            • D57.212 - Sickle-cell/Hb-C disease with splenic sequestration BILLABLE CODE
            • D57.213 - Sickle-cell/Hb-C disease with cerebral vascular involvement BILLABLE CODE NEW CODE
            • D57.218 - Sickle-cell/Hb-C disease with crisis with oth complication BILLABLE CODE NEW CODE
            • D57.219 - Sickle-cell/Hb-C disease with crisis, unspecified BILLABLE CODE
            • D57.3 - Sickle-cell trait BILLABLE CODE
            • D57.4 - Sickle-cell thalassemia NON-BILLABLE CODE
            • D57.40 - Sickle-cell thalassemia without crisis BILLABLE CODE
            • D57.41 - Sickle-cell thalassemia, unspecified, with crisis NON-BILLABLE CODE
            • D57.411 - Sickle-cell thalassemia, unsp, with acute chest syndrome BILLABLE CODE UPDATED CODE
            • D57.412 - Sickle-cell thalassemia, unsp, with splenic sequestration BILLABLE CODE UPDATED CODE
            • D57.413 - Sickle-cell thalassemia, unsp, with cerebral vascular invl BILLABLE CODE NEW CODE
            • D57.418 - Sickle-cell thalassemia, unsp, with crisis with oth comp BILLABLE CODE NEW CODE
            • D57.419 - Sickle-cell thalassemia, unspecified, with crisis BILLABLE CODE UPDATED CODE
            • D57.42 - Sickle-cell thalassemia beta zero without crisis BILLABLE CODE NEW CODE
            • D57.43 - Sickle-cell thalassemia beta zero with crisis NON-BILLABLE CODE
            • D57.431 - Sickle-cell thalassemia beta zero with acute chest syndrome BILLABLE CODE NEW CODE
            • D57.432 - Sickle-cell thalassemia beta zero with splenic sequestration BILLABLE CODE NEW CODE
            • D57.433 - Sickle-cell thalassemia beta zero with cereb vascular invl BILLABLE CODE NEW CODE
            • D57.438 - Sickle-cell thalassemia beta zero with crisis with oth comp BILLABLE CODE NEW CODE
            • D57.439 - Sickle-cell thalassemia beta zero with crisis, unspecified BILLABLE CODE NEW CODE
            • D57.44 - Sickle-cell thalassemia beta plus without crisis BILLABLE CODE NEW CODE
            • D57.45 - Sickle-cell thalassemia beta plus with crisis NON-BILLABLE CODE
            • D57.451 - Sickle-cell thalassemia beta plus with acute chest syndrome BILLABLE CODE NEW CODE
            • D57.452 - Sickle-cell thalassemia beta plus with splenic sequestration BILLABLE CODE NEW CODE
            • D57.453 - Sickle-cell thalassemia beta plus with cereb vascular invl BILLABLE CODE NEW CODE
            • D57.458 - Sickle-cell thalassemia beta plus with crisis with oth comp BILLABLE CODE NEW CODE
            • D57.459 - Sickle-cell thalassemia beta plus with crisis, unspecified BILLABLE CODE NEW CODE
            • D57.8 - Other sickle-cell disorders NON-BILLABLE CODE
            • D57.80 - Other sickle-cell disorders without crisis BILLABLE CODE
            • D57.81 - Other sickle-cell disorders with crisis NON-BILLABLE CODE
            • D57.811 - Other sickle-cell disorders with acute chest syndrome BILLABLE CODE
            • D57.812 - Other sickle-cell disorders with splenic sequestration BILLABLE CODE
            • D57.813 - Other sickle-cell disorders with cerebral vascular invl BILLABLE CODE NEW CODE
            • D57.818 - Other sickle-cell disorders with crisis with oth comp BILLABLE CODE NEW CODE
            • D57.819 - Other sickle-cell disorders with crisis, unspecified BILLABLE CODE