2024 ICD-10-CM Diagnosis Code E85.9

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Amyloid myopathy
• Amyloidosis
• Dilated cardiomyopathy due to amyloidosis
• Dilated cardiomyopathy due to infiltration
• Entrapment syndrome due to amyloid
• Factor X deficiency
• Factor X deficiency due to systemic amyloidosis
• Glomerular disorder due to amyloidosis
• Hypothyroidism due to amyloidosis
• Hypothyroidism due to infiltrative disease
• Infiltrative cardiomyopathy
• Myocardial degeneration
• Nephrotic syndrome associated with another disorder
• Nephrotic syndrome in amyloidosis
• Prothrombin complex deficiency
• Restrictive cardiomyopathy secondary to amyloidosis
• Secondary restrictive cardiomyopathy

Clinical Information

• Amyloid Neuropathies, Familial

  inherited disorders of the peripheral nervous system associated with the deposition of amyloid in nerve tissue. the different clinical types based on symptoms correspond to the presence of a variety of mutations in several different proteins including transthyretin (prealbumin); apolipoprotein a-i; and gelsolin.

• Amyloidosis

  a group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of amyloid. as the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. various signs and symptoms depend on the location and size of the deposits.

• Amyloidosis, Familial

  diseases in which there is a familial pattern of amyloidosis.

• Cerebral Amyloid Angiopathy, Familial

  a familial disorder marked by amyloid deposits in the walls of small and medium sized blood vessels of cerebral cortex and meninges.

• Immunoglobulin Light-chain Amyloidosis

  a nonproliferative disorder of the plasma cell characterized by excessive production and misfolding of immunoglobulin light chains that form insoluble amyloid fibrils (see amyloid deposits) in various tissues. clinical features include liver failure; multiple myeloma; nephrotic syndrome; restrictive cardiomyopathy, and neuropathies.

• Factor X Deficiency

  blood coagulation disorder usually inherited as an autosomal recessive trait, though it can be acquired. it is characterized by defective activity in both the intrinsic and extrinsic pathways, impaired thromboplastin time, and impaired prothrombin consumption.

• Amyloid

  a fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. this fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. deposits of amyloid in the form of amyloid plaques are associated with a variety of degenerative diseases. the amyloid structure has also been found in a number of functional proteins that are unrelated to disease.

• Myocardial Degeneration

  degeneration of myocardial tissue.

• Acquired Factor X Deficiency

  an acquired coagulation disorder characterized by the partial or complete absence of factor x activity in the blood.

• Factor X Deficiency

  a coagulation disorder characterized by the partial or complete absence of factor x activity in the blood.

• Hereditary Factor X Deficiency|Stuart-Prower Factor Deficiency

  a rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of factor x, resulting in bleeding.

E85.9 is grouped with Diagnostic Related Groups - MS-DRG Mapping

Diagnostic Related Groups (DRGs) are a classification system used to group together diagnosis codes for the purpose of reimbursement and healthcare management. DRGs are used to standardize the way hospitals and other providers are paid for inpatient services. In this system patients are grouped together based on their principal diagnosis in areas referred to as Major Diagnostic Categories (MDC). Once a patient is assigned a particular diagnostic category, providers receive a predetermined payment rate for the services rendered. This reimbursement rate is often fixed and is meant to cover the cost of care for that patient. Reimbursement is also affected by the relative weight of a diagnostic related group based on the severity of a patient's illness and the associated cost of care during hospitalization.

Diagnostic related groups encourage healthcare providers to focus on quality and efficiency in patient care while managing costs effectively. The diagnosis code is present in the following groups for version MS-DRG V41.0 applicable from 10/01/2023 through 09/30/2024.

MS-DRG	MS-DRG Title	MCD	Relative Weight
545	CONNECTIVE TISSUE DISORDERS WITH MCC	08	2.4932
546	CONNECTIVE TISSUE DISORDERS WITH CC	08	1.1993
547	CONNECTIVE TISSUE DISORDERS WITHOUT CC/MCC	08	0.8134

The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.

Convert E85.9 to ICD-9-CM

• ICD-9-CM Code: 277.30 - Amyloidosis NOS
  Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education

Amyloidosis

Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should.

There are three main types of amyloidosis:

• Primary - with no known cause
• Secondary - caused by another disease, including some types of cancer
• Familial - passed down through genes

Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated.

[Learn More in MedlinePlus]

Amyloidosis & Kidney Disease

Overview of amyloidosis, a condition where abnormal proteins called amyloid build up in organs and tissues, and how the condition affects the kidneys.
[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.