ICD-10 Diagnosis Code E85.8

Other amyloidosis

Diagnosis Code E85.8

ICD-10: E85.8
Short Description: Other amyloidosis
Long Description: Other amyloidosis
This is the 2018 version of the ICD-10-CM diagnosis code E85.8

Not Valid for Submission
The code E85.8 is a "header" and not valid for submission for HIPAA-covered transactions.

Replaced Code Additional informationCallout TooltipReplaced Code
The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2017. This codes was replaced for the FY 2018 (October 1, 2017-September 30, 2018).

This code was replaced in the 2018 ICD-10 code set with the code(s) listed below.
  • E85.81 - Light chain (AL) amyloidosis
  • E85.82 - Wild-type transthyretin-related (ATTR) amyloidosis
  • E85.89 - Other amyloidosis

Code Classification
  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Metabolic disorders (E70-E88)
      • Amyloidosis (E85)

Information for Medical Professionals

  • AA amyloid nephropathy
  • AA amyloidosis
  • Age-related amyloidosis
  • AL amyloidosis
  • Amyloid light-chain nephropathy
  • Amyloid myopathy
  • Amyloid nephropathy
  • Amyloidogenic transthyretin amyloidosis
  • Cerebral amyloid angiopathy
  • Cerebral amyloid angiopathy associated with systemic amyloidosis
  • Heredofamilial systemic amyloidosis affecting skin
  • Light chain disease
  • Myeloma-associated amyloidosis
  • Myeloma-associated primary systemic amyloidosis
  • Primary amyloidosis of light chain type
  • Primary sporadic amyloid myopathy
  • Primary systemic
  • Primary systemic
  • Primary systemic amyloidosis associated with occult plasma cell dyscrasia
  • Primary systemic amyloidosis with pseudoscleroderma
  • Senile systemic amyloidosis
  • Sporadic primary amyloidosis
  • Systemic amyloidosis
  • Systemic amyloidosis affecting skin
  • Systemic amyloidosis affecting skin

Information for Patients


Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should.

There are three main types of amyloidosis:

  • Primary - with no known cause
  • Secondary - caused by another disease, including some types of cancer
  • Familial - passed down through genes

Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated.

  • Cardiac amyloidosis (Medical Encyclopedia)
  • Hereditary amyloidosis (Medical Encyclopedia)
  • Primary amyloidosis (Medical Encyclopedia)
  • Secondary systemic amyloidosis (Medical Encyclopedia)

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