1. Home
  2. ICD-10-CM Codes
  3. E00–E89
  4. E70-E88
  5. E75
  6. 2024 ICD-10-CM Code E75
Version 2024
Non-Billable Code

2024 ICD-10-CM Diagnosis Code E75

Disorders of sphingolipid metabolism and other lipid storage disorders

ICD-10-CM Code:
E75
ICD-10 Code for:
Disord of sphingolipid metab and oth lipid storage disorders
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    (E00–E89)
    • Metabolic disorders
      (E70-E88)
      • Disorders of sphingolipid metabolism and other lipid storage disorders
        (E75)

E75 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of disorders of sphingolipid metabolism and other lipid storage disorders. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Disord of sphingolipid metab and oth lipid storage disorders

Non-specific codes like E75 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for disord of sphingolipid metab and oth lipid storage disorders:

  • E75.0 for GM2 gangliosidosis - NON-BILLABLE CODE

  • Use E75.00 for GM2 gangliosidosis, unspecified - BILLABLE CODE

  • Use E75.01 for Sandhoff disease - BILLABLE CODE

  • Use E75.02 for Tay-Sachs disease - BILLABLE CODE

  • Use E75.09 for Other GM2 gangliosidosis - BILLABLE CODE

  • E75.1 for Other and unspecified gangliosidosis - NON-BILLABLE CODE

  • Use E75.10 for Unspecified gangliosidosis - BILLABLE CODE

  • Use E75.11 for Mucolipidosis IV - BILLABLE CODE

  • Use E75.19 for Other gangliosidosis - BILLABLE CODE

  • E75.2 for Other sphingolipidosis - NON-BILLABLE CODE

  • Use E75.21 for Fabry (-Anderson) disease - BILLABLE CODE

  • Use E75.22 for Gaucher disease - BILLABLE CODE

  • Use E75.23 for Krabbe disease - BILLABLE CODE

  • E75.24 for Niemann-Pick disease - NON-BILLABLE CODE

  • Use E75.25 for Metachromatic leukodystrophy - BILLABLE CODE

  • Use E75.26 for Sulfatase deficiency - BILLABLE CODE

  • Use E75.27 for Pelizaeus-Merzbacher disease - BILLABLE CODE

  • Use E75.28 for Canavan disease - BILLABLE CODE

  • Use E75.29 for Other sphingolipidosis - BILLABLE CODE

  • Use E75.3 for Sphingolipidosis, unspecified - BILLABLE CODE

  • Use E75.4 for Neuronal ceroid lipofuscinosis - BILLABLE CODE

  • Use E75.5 for Other lipid storage disorders - BILLABLE CODE

  • Use E75.6 for Lipid storage disorder, unspecified - BILLABLE CODE

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

Patient Education


Genetic Brain Disorders

A genetic brain disorder is caused by a variation or a mutation in a gene. A variation is a different form of a gene. A mutation is a change in a gene. Genetic brain disorders affect the development and function of the brain.

Some genetic brain disorders are due to random gene mutations or mutations caused by environmental exposure, such as cigarette smoke. Other disorders are inherited, which means that a mutated gene or group of genes is passed down through a family. They can also be due to a combination of both genetic changes and other outside factors.

Some examples of genetic brain disorders include:

  • Leukodystrophies
  • Phenylketonuria
  • Tay-Sachs disease
  • Wilson disease

Many people with genetic brain disorders fail to produce enough of certain proteins that influence brain development and function. These brain disorders can cause serious problems that affect the nervous system. Some have treatments to control symptoms. Some are life-threatening.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.