Diagnosis Code E27.1
Information for Medical Professionals
The diagnosis code E27.1 is grouped in the following Diagnostic Related Group(s) (MS-DRG V35.0)
- 643 - ENDOCRINE DISORDERS WITH MCC
- 644 - ENDOCRINE DISORDERS WITH CC
- 645 - ENDOCRINE DISORDERS WITHOUT CC/MCC
Convert to ICD-9 General Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.
- 255.41 - Glucocorticoid deficient (approximate) Approximate Flag
The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
- Addison's disease
- Addison's disease due to autoimmunity
- Buccal pigmentation due to Addison's disease
- Congenital primary adrenocortical hypofunction
- Endocrine myopathy
- Hereditary adrenal unresponsiveness to corticotropin
- Hypermelanosis due to endocrine disorder
- Myopathy in Addison's disease
- Primary adrenocortical insufficiency
Index of Diseases and Injuries
References found for the code E27.1 in the Index of Diseases and Injuries:
- Inclusion Terms: Inclusion terms
List of terms is included under some codes. These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Addison's disease
- Autoimmune adrenalitis
- Type 1 Excludes Notes: Type 1 Excludes Notes
A type 1 Excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- Addison only phenotype adrenoleukodystrophy (E71.528)
- amyloidosis (E85.-)
- tuberculous Addison's disease (A18.7)
- Waterhouse-Friderichsen syndrome (A39.1)
Information for Patients
Also called: Adrenal insufficiency, Adrenocortical hypofunction, Hypocortisolism
Your adrenal glands are just above your kidneys. The outside layer of these glands makes hormones that help your body respond to stress and regulate your blood pressure and water and salt balance. Addison disease happens if the adrenal glands don't make enough of these hormones.
A problem with your immune system usually causes Addison disease. The immune system mistakenly attacks your own tissues, damaging your adrenal glands. Other causes include infections and cancer.
- Weight loss
- Muscle weakness
- Fatigue that gets worse over time
- Low blood pressure
- Patchy or dark skin
Lab tests can confirm that you have Addison disease. If you don't treat it, it can be fatal. You will need to take hormone pills for the rest of your life. If you have Addison disease, you should carry an emergency ID. It should say that you have the disease, list your medicines and say how much you need in an emergency.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases
- ACTH (cosyntropin) stimulation test (Medical Encyclopedia)
- ACTH blood test (Medical Encyclopedia)
- Acute adrenal crisis (Medical Encyclopedia)
- Addison disease (Medical Encyclopedia)
- Cortisol level (Medical Encyclopedia)
Autoimmune Addison disease Autoimmune Addison disease affects the function of the adrenal glands, which are small hormone-producing glands located on top of each kidney. It is classified as an autoimmune disorder because it results from a malfunctioning immune system that attacks the adrenal glands. As a result, the production of several hormones is disrupted, which affects many body systems.The signs and symptoms of autoimmune Addison disease can begin at any time, although they most commonly begin between ages 30 and 50. Common features of this condition include extreme tiredness (fatigue), nausea, decreased appetite, and weight loss. In addition, many affected individuals have low blood pressure (hypotension), which can lead to dizziness when standing up quickly; muscle cramps; and a craving for salty foods. A characteristic feature of autoimmune Addison disease is abnormally dark areas of skin (hyperpigmentation), especially in regions that experience a lot of friction, such as the armpits, elbows, knuckles, and palm creases. The lips and the inside lining of the mouth can also be unusually dark. Because of an imbalance of hormones involved in development of sexual characteristics, women with this condition may lose their underarm and pubic hair.Other signs and symptoms of autoimmune Addison disease include low levels of sugar (hypoglycemia) and sodium (hyponatremia) and high levels of potassium (hyperkalemia) in the blood. Affected individuals may also have a shortage of red blood cells (anemia) and an increase in the number of white blood cells (lymphocytosis), particularly those known as eosinophils (eosinophilia).Autoimmune Addison disease can lead to a life-threatening adrenal crisis, characterized by vomiting, abdominal pain, back or leg cramps, and severe hypotension leading to shock. The adrenal crisis is often triggered by a stressor, such as surgery, trauma, or infection.Individuals with autoimmune Addison disease or their family members can have another autoimmune disorder, most commonly autoimmune thyroid disease or type 1 diabetes.