ICD-10 Diagnosis Code E22.0

Acromegaly and pituitary gigantism

Diagnosis Code E22.0

ICD-10: E22.0
Short Description: Acromegaly and pituitary gigantism
Long Description: Acromegaly and pituitary gigantism
This is the 2018 version of the ICD-10-CM diagnosis code E22.0

Valid for Submission
The code E22.0 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Disorders of other endocrine glands (E20-E35)
      • Hyperfunction of pituitary gland (E22)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code E22.0 is grouped in the following Diagnostic Related Group(s) (MS-DRG V34.0)


Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Acromegalic facies
  • Acromegalic feet
  • Acromegaly
  • Arthropathy associated with acromegaly
  • Cutis verticis gyrata with acromegaloid phenotype
  • Dermatosis of scalp
  • Endocrine myopathy
  • Eunuchoid gigantism
  • Gigantism
  • Gigantism and acromegaly
  • Gigantism due to somatostatin deficiency
  • Hypermelanosis due to acromegaly
  • Hypermelanosis due to endocrine disorder
  • Hypersomatotropic gigantism
  • Large, broad feet
  • Multiple malformation syndrome with early overgrowth
  • Myopathy in acromegaly
  • Neuropathy in acromegaly
  • Overproduction of growth hormone
  • Sotos' syndrome
  • Testicular hyperfunction

Index of Diseases and Injuries
References found for the code E22.0 in the Index of Diseases and Injuries:

Information for Patients

Pituitary Disorders

Your pituitary gland is a pea-sized gland at the base of your brain. The pituitary is the "master control gland" - it makes hormones that affect growth and the functions of other glands in the body.

With pituitary disorders, you often have too much or too little of one of your hormones. Injuries can cause pituitary disorders, but the most common cause is a pituitary tumor.

  • ACTH (cosyntropin) stimulation test (Medical Encyclopedia)
  • ACTH blood test (Medical Encyclopedia)
  • Empty sella syndrome (Medical Encyclopedia)
  • Follicle-stimulating hormone (FSH) blood test (Medical Encyclopedia)
  • Gigantism (Medical Encyclopedia)
  • Growth hormone stimulation test (Medical Encyclopedia)
  • Hypopituitarism (Medical Encyclopedia)
  • Luteinizing hormone (LH) blood test (Medical Encyclopedia)
  • Pituitary infarction (Medical Encyclopedia)

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Sotos syndrome Sotos syndrome is a disorder characterized by a distinctive facial appearance, overgrowth in childhood, and learning disabilities or delayed development of mental and movement abilities. Characteristic facial features include a long, narrow face; a high forehead; flushed (reddened) cheeks; and a small, pointed chin. In addition, the outside corners of the eyes may point downward (down-slanting palpebral fissures). This facial appearance is most notable in early childhood. Affected infants and children tend to grow quickly; they are significantly taller than their siblings and peers and have an unusually large head. However, adult height is usually in the normal range.People with Sotos syndrome often have intellectual disability, and most also have behavioral problems. Frequent behavioral issues include attention deficit hyperactivity disorder (ADHD), phobias, obsessions and compulsions, tantrums, and impulsive behaviors. Problems with speech and language are also common. Affected individuals often have a stutter, a monotone voice, and problems with sound production. Additionally, weak muscle tone (hypotonia) may delay other aspects of early development, particularly motor skills such as sitting and crawling.Other signs and symptoms of Sotos syndrome can include an abnormal side-to-side curvature of the spine (scoliosis), seizures, heart or kidney defects, hearing loss, and problems with vision. Some infants with this disorder experience yellowing of the skin and whites of the eyes (jaundice) and poor feeding.A small percentage of people with Sotos syndrome have developed cancer, most often in childhood, but no single form of cancer occurs most frequently with this condition. It remains uncertain whether Sotos syndrome increases the risk of specific types of cancer. If people with this disorder have an increased cancer risk, it is only slightly greater than that of the general population.
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