ICD-10 Diagnosis Code D89.89

Oth disrd involving the immune mechanism, NEC

Diagnosis Code D89.89

ICD-10: D89.89
Short Description: Oth disrd involving the immune mechanism, NEC
Long Description: Other specified disorders involving the immune mechanism, not elsewhere classified
This is the 2018 version of the ICD-10-CM diagnosis code D89.89

Valid for Submission
The code D89.89 is valid for submission for HIPAA-covered transactions.

Replaced Code Additional informationCallout TooltipReplaced Code
The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2017. This codes was replaced for the FY 2018 (October 1, 2017-September 30, 2018).

This code was replaced in the 2018 ICD-10 code set with the code(s) listed below.
  • D89.40 - Mast cell activation, unspecified
  • D89.41 - Monoclonal mast cell activation syndrome
  • D89.42 - Idiopathic mast cell activation syndrome
  • D89.43 - Secondary mast cell activation
  • D89.49 - Other mast cell activation disorder

Code Classification
  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)
    • Certain disorders involving the immune mechanism (D80-D89)
      • Oth disorders involving the immune mechanism, NEC (D89)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code D89.89 is grouped in the following Diagnostic Related Group(s) (MS-DRG V34.0)


Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Antibody-mediated cytolysis
  • Autoimmune disorder of inner ear
  • Autoinflammation, lipodystrophy and dermatosis syndrome
  • Bacillus Calmette-Guerin granuloma
  • Cytokine-associated toxicity
  • Deficiency of immunoglobulin
  • Familial immunoglobulin hypercatabolism
  • Immune system complication of procedure
  • Immunoglobulin hypercatabolism
  • Infection caused by Mycobacterium bovis
  • Inflammatory disorder of immune system
  • Isoimmunization
  • Primary immunoglobulin catabolism abnormality
  • Primary immunoglobulin catabolism abnormality
  • Tuftsin deficiency

Index of Diseases and Injuries
References found for the code D89.89 in the Index of Diseases and Injuries:

Information for Patients

Immune System and Disorders

Your immune system is a complex network of cells, tissues, and organs that work together to defend against germs. It helps your body to recognize these "foreign" invaders. Then its job is to keep them out, or if it can't, to find and destroy them.

If your immune system cannot do its job, the results can be serious. Disorders of the immune system include

  • Allergy and asthma - immune responses to substances that are usually not harmful
  • Immune deficiency diseases - disorders in which the immune system is missing one or more of its parts
  • Autoimmune diseases - diseases causing your immune system to attack your own body's cells and tissues by mistake

NIH: National Institute of Allergy and Infectious Diseases

  • Agammaglobulinemia (Medical Encyclopedia)
  • Aging changes in immunity (Medical Encyclopedia)
  • Chronic granulomatous disease (Medical Encyclopedia)
  • Graft-versus-host disease (Medical Encyclopedia)
  • Histiocytosis (Medical Encyclopedia)
  • Hyperimmunoglobulin E syndrome (Medical Encyclopedia)
  • Immune response (Medical Encyclopedia)
  • Immunodeficiency disorders (Medical Encyclopedia)
  • Selective deficiency of IgA (Medical Encyclopedia)

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