ICD-10 Diagnosis Code C45.0

Mesothelioma of pleura

Diagnosis Code C45.0

ICD-10: C45.0
Short Description: Mesothelioma of pleura
Long Description: Mesothelioma of pleura
This is the 2018 version of the ICD-10-CM diagnosis code C45.0

Valid for Submission
The code C45.0 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Neoplasms (C00–D48)
    • Malignant neoplasms of mesothelial and soft tissue (C45-C49)
      • Mesothelioma (C45)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code C45.0 is grouped in the following Diagnostic Related Group(s) (MS-DRG V34.0)


Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Malignant mesothelioma of pleura
  • Malignant tumor of mesothelial tissue
  • Mesothelioma
  • Primary malignant neoplasm of pleura

Index of Diseases and Injuries
References found for the code C45.0 in the Index of Diseases and Injuries:

Information for Patients


Also called: Malignant mesothelioma

The tissue that lines your lungs, stomach, heart, and other organs is called mesothelium. Mesothelioma is a tumor of that tissue. It usually starts in the lungs, but can also start in the abdomen or other organs. It can be benign (not cancer) or malignant (cancer.)

Malignant mesothelioma is a rare but serious type of cancer. Most people who get it have worked on jobs where they inhaled asbestos particles. After being exposed to asbestos, it usually takes a long time for the disease to form.

Symptoms include

  • Trouble breathing
  • Pain under the rib cage
  • Pain, swelling, or lumps in the abdomen
  • Weight loss for no known reason

Sometimes it is hard to tell the difference between malignant mesothelioma and lung cancer. Your doctor uses imaging tests and a biopsy to make the diagnosis. Malignant mesothelioma is often found when it is advanced. This makes it harder to treat. Treatment may include surgery, radiation, and/or chemotherapy.

NIH: National Cancer Institute

  • Mesothelioma - benign-fibrous (Medical Encyclopedia)
  • Mesothelioma - malignant (Medical Encyclopedia)
  • Understanding Chemotherapy - NIH - Easy-to-Read (National Cancer Institute)
  • What to Know about External Beam Radiation Therapy - NIH - Easy-to-Read (National Cancer Institute)

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