2024 ICD-10-CM Diagnosis Code Z14.8

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Asymptomatic carrier of hereditary factor VIII deficiency disease
• Carrier of alpha thalassemia
• Carrier of Becker muscular dystrophy
• Carrier of beta thalassemia
• Carrier of Bloom syndrome
• Carrier of Canavan disease
• Carrier of Charcot-Marie-Tooth disease
• Carrier of chromosome disorder
• Carrier of chromosome translocation
• Carrier of classical phenylketonuria
• Carrier of Cowden syndrome
• Carrier of Duchenne muscular dystrophy
• Carrier of familial adenomatous polyposis
• Carrier of familial dysautonomia
• Carrier of fragile X chromosome
• Carrier of galactosemia
• Carrier of Gaucher disease
• Carrier of glycogen storage disease
• Carrier of hemochromatosis
• Carrier of hemochromatosis HFE gene mutation
• Carrier of hemoglobinopathy C disorder
• Carrier of hemoglobinopathy disorder
• Carrier of hemoglobinopathy E disorder
• Carrier of hereditary factor IX deficiency disease
• Carrier of hereditary factor VIII deficiency disease
• Carrier of hereditary factor VIII deficiency disease
• Carrier of heritable cancer
• Carrier of high risk cancer mutation gene
• Carrier of mitochondrial defect
• Carrier of muscular dystrophy
• Carrier of myotonic dystrophy
• Carrier of nonsyndromic deafness
• Carrier of sickle cell gene mutation
• Carrier of spinal muscular atrophy
• Carrier of Tay Sachs disease gene mutation
• Carrier of von Willebrand disease
• Familial disease
• Fragile X chromosome
• Fragile X syndrome
• Gastrointestinal hormone level - finding
• Genetic disorder carrier
• Genetic predisposition
• Hemophilia carrier
• Hereditary disease
• Manifesting female carrier of X-linked muscular dystrophy
• Manifesting female carrier of X-linked muscular dystrophy
• Maternally inherited mitochondrial deoxyribonucleic acid disease
• Symptomatic carrier of hereditary factor VIII deficiency disease
• Symptomatic form of fragile X syndrome in female carrier
• Symptomatic form of muscular dystrophy of Duchenne and Becker in female carrier
• X-linked muscular dystrophy with abnormal dystrophin
• X-linked muscular dystrophy with abnormal dystrophin
• X-linked muscular dystrophy with limb girdle distribution
• X-linked muscular dystrophy with limb girdle distribution

Clinical Information

• Fragile X Syndrome

  a condition characterized genotypically by mutation of the distal end of the long arm of the x chromosome (at gene loci fraxa or fraxe) and phenotypically by cognitive impairment, hyperactivity, seizures, language delay, and enlargement of the ears, head, and testes. intellectual disability occurs in nearly all males and roughly 50% of females with the full mutation of fraxa. (from menkes, textbook of child neurology, 5th ed, p226)

• Fragile X Syndrome

  a genetic syndrome caused by mutations in the fmr1 gene which is responsible for the expression of the fragile x mental retardation 1 protein. this protein participates in neural development. this syndrome is manifested with mental, emotional, behavioral, physical, and learning disabilities.

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

• Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)

Z14.8 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA Indicator	Reason for Code	CMS will pay the CC/MCC DRG?
Y	Diagnosis was present at time of inpatient admission.	YES
N	Diagnosis was not present at time of inpatient admission.	NO
U	Documentation insufficient to determine if the condition was present at the time of inpatient admission.	NO
W	Clinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.	YES
1	Unreported/Not used - Exempt from POA reporting.	NO

Convert Z14.8 to ICD-9-CM

• ICD-9-CM Code: V83.89 - Genetic carrier stat NEC

Patient Education

Genetic Disorders

Genes are the building blocks of heredity. They are passed from parent to child. They hold DNA, the instructions for making proteins. Proteins do most of the work in cells. They move molecules from one place to another, build structures, break down toxins, and do many other maintenance jobs.

Sometimes there is a mutation, a change in a gene or genes. The mutation changes the gene's instructions for making a protein, so the protein does not work properly or is missing entirely. This can cause a medical condition called a genetic disorder.

You can inherit a gene mutation from one or both parents. A mutation can also happen during your lifetime.

There are three types of genetic disorders:

• Single-gene disorders, where a mutation affects one gene. Sickle cell anemia is an example.
• Chromosomal disorders, where chromosomes (or parts of chromosomes) are missing or changed. Chromosomes are the structures that hold our genes. Down syndrome is a chromosomal disorder.
• Complex disorders, where there are mutations in two or more genes. Often your lifestyle and environment also play a role. Colon cancer is an example.

Genetic tests on blood and other tissue can identify genetic disorders.

NIH: National Library of Medicine

[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.