2024 ICD-10-CM Diagnosis Code T50.8X5A

Adverse effect of diagnostic agents, initial encounter

ICD-10-CM Code:
T50.8X5A
ICD-10 Code for:
Adverse effect of diagnostic agents, initial encounter
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
        (T50)

T50.8X5A is a billable diagnosis code used to specify a medical diagnosis of adverse effect of diagnostic agents, initial encounter. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

T50.8X5A is an initial encounter code, includes a 7th character and should be used while the patient is receiving active treatment for a condition like adverse effect of diagnostic agents. According to ICD-10-CM Guidelines an "initial encounter" doesn't necessarily means "initial visit". The 7th character should be used when the patient is undergoing active treatment regardless if new or different providers saw the patient over the course of a treatment. The appropriate 7th character codes should also be used even if the patient delayed seeking treatment for a condition.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acute kidney injury caused by contrast agent
  • Acute kidney injury following administration of contrast media
  • Acute kidney injury following administration of contrast media
  • Acute renal failure due to procedure
  • Adverse reaction to oral contrast media
  • Allergic reaction to radiocontrast media
  • Anaphylaxis caused by allergy skin test
  • Aseptic peritonitis
  • Barium granuloma of colon
  • Barium granuloma of intestine
  • Barium peritonitis
  • Barium sulfate embolism
  • Chemical peritonitis
  • Contrast media adverse reaction
  • Contrast media adverse reaction
  • Contrast media adverse reaction
  • Diagnostic agent adverse reaction
  • Diagnostic dye adverse reaction
  • Granuloma of intestine
  • Granuloma of intestine
  • Hyperthyroidism secondary to radio contrast dye
  • Iodine-induced hyperthyroidism
  • Magnetic resonance imaging contrast media adverse reaction
  • Non-allergic hypersensitivity reaction caused by radiocontrast media
  • Tuberculin adverse reaction
  • X-ray contrast media adverse reaction

Clinical Classification

Clinical Information

  • Chemical Peritonitis

    a non-infectious inflammation of the peritoneum.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Convert T50.8X5A to ICD-9-CM

  • ICD-9-CM Code: 995.29 - Adv eff med/biol NEC/NOS
    Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.
  • ICD-9-CM Code: E947.8 - Adv eff medicinal NEC
    Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.

Table of Drugs and Chemicals

The parent code T50.8X5 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
Acetrizoate (sodium)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Acetrizoic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
AdipiodoneT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
AmetazoleT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
AmidotrizoateT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Aminohippuric acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Angio-ConrayT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
AzuresinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
BentiromideT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
BetazoleT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
BiligrafinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
BilopaqueT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
BromsulfophthaleinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
BunamiodylT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
CardiografinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Cardio-greenT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
CeruletideT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
CholebrineT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
CholecystokininT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
CholografinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
CoccidioidinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Congo redT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Contrast medium, radiographyT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Diagnostic agent NECT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
DiatrizoateT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
DiodoneT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Ethiodized oil (131 I)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Evans blueT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Fludeoxyglucose (18F)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
FluoresceinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Frei antigenT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Gadopentetic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
GastrografinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
HistalogT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Histamine (phosphate)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
HistoplasminT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
HypaqueT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Indigo carmineT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Indocyanine greenT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
InulinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iobenzamic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iocarmic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iocetamic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IodamideT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IodinatedT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iodinated
  »contrast medium
T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iodinated
  »glycerol
T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iodinated
  »human serum albumin (131I)
T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IodipamideT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iodized (poppy seed) oilT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iodocholesterol (131I)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iodohippuric acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iodopanoic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iodophthalein (sodium)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IodopyracetT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iodoxamic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IofendylateT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Ioglycamic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IohexolT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IopamidolT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iopanoic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iophenoic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iopodate, sodiumT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iopodic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IopromideT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IopydolT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iotalamic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IothalamateT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IotrolT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IotrolanT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IotroxateT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Iotroxic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IoversolT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IoxaglateT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Ioxaglic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Ioxitalamic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Ipodate, calciumT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
IprofeninT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
LidofeninT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Lygranum (skin test)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Lymphogranuloma venereum antigenT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Methiodal sodiumT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
MetrizamideT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Metrizoic acidT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
MetyraponeT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
OragrafinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Penicilloyl polylysineT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
PentagastrinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
PeptavlonT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
PhenobutiodilT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
PhenolsulfonphthaleinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
PropyliodoneT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
PSP (phenolsulfonphthalein)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Radioactive drug NECT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Radio-opaque (drugs) (materials)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
RenografinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Rose bengal sodium (131I)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Rubidium chloride Rb82T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
SecretinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Selenomethionine (75Se)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
SincalideT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Sulfan blue (diagnostic dye)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Sulfobromophthalein (sodium)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
SulfobromphthaleinT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Sulfonphthal, sulfonphtholT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Sulkowitch's reagentT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Sulphan blueT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
TelepaqueT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Thorium dioxide suspensionT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Toxin, diphtheria (Schick Test)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Tuberculin, purified protein derivative (PPD)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
TyropanoateT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
UrokonT50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6
Xenon (127Xe) (133Xe)T50.8X1T50.8X2T50.8X3T50.8X4T50.8X5T50.8X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.