2024 ICD-10-CM Diagnosis Code T50.5X5

Adverse effect of appetite depressants

ICD-10-CM Code:
T50.5X5
ICD-10 Code for:
Adverse effect of appetite depressants
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
        (T50)

T50.5X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of appetite depressants. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of appetite depressants

Non-specific codes like T50.5X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of appetite depressants:

  • Use T50.5X5A for initial encounter - BILLABLE CODE

  • Use T50.5X5D for subsequent encounter - BILLABLE CODE

  • Use T50.5X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Amphetamine group adverse reaction
  • Amphetamine group adverse reaction
  • Amphetamine group adverse reaction
  • Centrally acting appetite suppressant adverse reaction
  • Dexfenfluramine adverse reaction
  • Diethylpropion adverse reaction
  • Fenfluramine adverse reaction
  • Mazindol adverse reaction
  • Phentermine adverse reaction

Clinical Information

  • Aminorex

    an amphetamine-like anorectic agent. it may cause pulmonary hypertension.
  • Benzphetamine

    a sympathomimetic agent with properties similar to dextroamphetamine. it is used in the treatment of obesity. (from martindale, the extra pharmacopoeia, 30th ed, p1222)
  • Chlorphentermine

    a sympathomimetic agent that was formerly used as an anorectic. it has properties similar to those of dextroamphetamine. it has been implicated in lipid storage disorders and pulmonary hypertension. (from martindale, the extra pharmacopoeia, 30th ed, p1223)
  • Dexfenfluramine

    the s-isomer of fenfluramine. it is a serotonin agonist and is used as an anorectic. unlike fenfluramine, it does not possess any catecholamine agonist activity.
  • Diethylpropion

    a appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. it is also considered to be among the safest for patients with hypertension. (from ama drug evaluations annual, 1994, p2290)
  • Fenfluramine

    a centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.
  • Mazindol

    tricyclic anorexigenic agent unrelated to and less toxic than amphetamine, but with some similar side effects. it inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
  • Phenmetrazine

    a sympathomimetic drug used primarily as an appetite depressant. its actions and mechanisms are similar to dextroamphetamine.
  • Phentermine

    a central nervous system stimulant and sympathomimetic with actions and uses similar to those of dextroamphetamine. it has been used most frequently in the treatment of obesity.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AmfepramoneT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
AminorexT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Anorexiant (central)T50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Anorexic agentsT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Appetite depressants, centralT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
BenzamphetamineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
BenzfetamineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
BenzphetamineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Bulk fillerT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Bulk filler
  »cathartic
T50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
CathineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
ChlorphentermineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
ClobenzorexT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
CloforexT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
ClortermineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Depressant, appetiteT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
DepressantT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Depressant
  »appetite (central)
T50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Depressant
  »cardiac
T50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Depressant
  »central nervous system (anesthetic) [See Also: Central nervous system, depressants]
T50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Depressant
  »central nervous system (anesthetic) [See Also: Central nervous system, depressants]
    »general anesthetic
T50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Depressant
  »central nervous system (anesthetic) [See Also: Central nervous system, depressants]
    »muscle tone
T50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Depressant
  »muscle tone, central
T50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
Depressant
  »psychotherapeutic
T50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
DexfenfluramineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
DiethylpropionT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
FenbutrazateT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
FenfluramineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
FenproporexT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
LevopropylhexedrineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
MazindolT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
MefenorexT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
NorpseudoephedrineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
OxazimedrineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
PhenbutrazateT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
PhendimetrazineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
PhenmetrazineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6
PhentermineT50.5X1T50.5X2T50.5X3T50.5X4T50.5X5T50.5X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.