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  6. 2024 ICD-10-CM Code T48.29
Version 2024
Non-Billable Code

2024 ICD-10-CM Diagnosis Code T48.29

Poisoning by, adverse effect of and underdosing of other drugs acting on muscles

ICD-10-CM Code:
T48.29
ICD-10 Code for:
Drugs acting on muscles
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system
        (T48)

T48.29 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of poisoning by, adverse effect of and underdosing of other drugs acting on muscles. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Drugs acting on muscles

Non-specific codes like T48.29 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for drugs acting on muscles:

  • T48.291 for Poisoning by other drugs acting on muscles, accidental (unintentional) - NON-BILLABLE CODE

  • Use T48.291A for initial encounter - BILLABLE CODE

  • Use T48.291D for subsequent encounter - BILLABLE CODE

  • Use T48.291S for sequela - BILLABLE CODE

  • T48.292 for Poisoning by other drugs acting on muscles, intentional self-harm - NON-BILLABLE CODE

  • Use T48.292A for initial encounter - BILLABLE CODE

  • Use T48.292D for subsequent encounter - BILLABLE CODE

  • Use T48.292S for sequela - BILLABLE CODE

  • T48.293 for Poisoning by other drugs acting on muscles, assault - NON-BILLABLE CODE

  • Use T48.293A for initial encounter - BILLABLE CODE

  • Use T48.293D for subsequent encounter - BILLABLE CODE

  • Use T48.293S for sequela - BILLABLE CODE

  • T48.294 for Poisoning by other drugs acting on muscles, undetermined - NON-BILLABLE CODE

  • Use T48.294A for initial encounter - BILLABLE CODE

  • Use T48.294D for subsequent encounter - BILLABLE CODE

  • Use T48.294S for sequela - BILLABLE CODE

  • T48.295 for Adverse effect of other drugs acting on muscles - NON-BILLABLE CODE

  • Use T48.295A for initial encounter - BILLABLE CODE

  • Use T48.295D for subsequent encounter - BILLABLE CODE

  • Use T48.295S for sequela - BILLABLE CODE

  • T48.296 for Underdosing of other drugs acting on muscles - NON-BILLABLE CODE

  • Use T48.296A for initial encounter - BILLABLE CODE

  • Use T48.296D for subsequent encounter - BILLABLE CODE

  • Use T48.296S for sequela - BILLABLE CODE

Coding Guidelines

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system (T48). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.