ICD-10 Code T46.995

Adverse effect of other agents primarily affecting the cardiovascular system

Version 2019 Replaced Code Non-Billable Code Adverse Effect
ICD-10:T46.995
Short Description:Adverse effect of agents aff the cardiovascular sys
Long Description:Adverse effect of other agents primarily affecting the cardiovascular system

Not Valid for Submission

ICD-10 T46.995 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of other agents primarily affecting the cardiovascular system. The code is NOT valid for the year 2019 for the submission of HIPAA-covered transactions.

Consider the following ICD-10 codes with a higher level of specificity:

  • T46.995A - Adverse effect of other agents primarily affecting the cardiovascular system, initial encounter
  • T46.995D - Adverse effect of other agents primarily affecting the cardiovascular system, subsequent encounter
  • T46.995S - Adverse effect of other agents primarily affecting the cardiovascular system, sequela

Deleted Code

This code was deleted in the 2019 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2018. This code was replaced for the FY 2019 (October 1, 2018 - September 30, 2019).

  • K59.03 - Drug induced constipation

Code Classification

  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Agents primarily affecting the cardiovascular system (T46)

Information for Medical Professionals

Diagnostic Related Groups

The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC). The diagnosis code T46.995 is grouped in the following groups for version MS-DRG V36.0 applicable from 10/01/2018 through 09/30/2019.

  • 922 - OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITH MCC
  • 923 - OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITHOUT MCC
  • 949 - AFTERCARE WITH CC/MCC
  • 950 - AFTERCARE WITHOUT CC/MCC

Synonyms

The following clinical terms are approximate synonyms:

  • Adverse reaction to adrenochrome derivative
  • Adverse reaction to capillary-active drug
  • Cardiac inotropic agent adverse reaction
  • Cardiac inotropic agent adverse reaction
  • Enoximone adverse reaction
  • Milrinone adverse reaction
  • Phosphodiesterase inhibitor adverse reaction
  • Phosphodiesterase inhibitor adverse reaction
  • Vasoconstrictor adverse reaction

Table of Drugs and Chemicals

The code T46.995 is included in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. Use as many codes as necessary to describe all reported drugs, medicinal or chemical substances.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
self-harm
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
Aconite (wild)T46.991T46.992T46.993T46.994T46.995T46.996
AconitineT46.991T46.992T46.993T46.994T46.995T46.996
Aconitum feroxT46.991T46.992T46.993T46.994T46.995T46.996
AdrenochromeT46.991T46.992T46.993T46.994T46.995T46.996
Adrenochrome
  » (mono) semicarbazone
T46.991T46.992T46.993T46.994T46.995T46.996
Adrenochrome
  »derivative
T46.991T46.992T46.993T46.994T46.995T46.996
AurantiinT46.991T46.992T46.993T46.994T46.995T46.996
BenzopyroneT46.991T46.992T46.993T46.994T46.995T46.996
Bioflavonoid (s)T46.991T46.992T46.993T46.994T46.995T46.996
Chlorisondamine chlorideT46.991T46.992T46.993T46.994T46.995T46.996
DiosminT46.991T46.992T46.993T46.994T46.995T46.996
EscinT46.991T46.992T46.993T46.994T46.995T46.996
EthoxazorutosideT46.991T46.992T46.993T46.994T46.995T46.996
Flavodic acidT46.991T46.992T46.993T46.994T46.995T46.996
HesperidinT46.991T46.992T46.993T46.994T46.995T46.996
LeucocianidolT46.991T46.992T46.993T46.994T46.995T46.996
MetescufyllineT46.991T46.992T46.993T46.994T46.995T46.996
NaftazoneT46.991T46.992T46.993T46.994T46.995T46.996
PhenopyrazoneT46.991T46.992T46.993T46.994T46.995T46.996
PholedrineT46.991T46.992T46.993T46.994T46.995T46.996
RutinumT46.991T46.992T46.993T46.994T46.995T46.996
RutosideT46.991T46.992T46.993T46.994T46.995T46.996
TribenosideT46.991T46.992T46.993T46.994T46.995T46.996
TroxerutinT46.991T46.992T46.993T46.994T46.995T46.996

Information for Patients


Drug Reactions

Also called: Side effects

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as ginkgo and blood thinners
  • Drugs and diseases, such as aspirin and peptic ulcers

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.

  • Angioedema (Medical Encyclopedia)
  • Drug allergies (Medical Encyclopedia)
  • Drug-induced diarrhea (Medical Encyclopedia)
  • Drug-induced tremor (Medical Encyclopedia)
  • Taking multiple medicines safely (Medical Encyclopedia)

[Read More]

ICD-10 Footnotes

General Equivalence Map Definitions
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.