ICD-10 Code T46.5X5

Adverse effect of other antihypertensive drugs

Version 2019 Replaced Code Non-Billable Code Adverse Effect

Not Valid for Submission

T46.5X5 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of other antihypertensive drugs. The code is NOT valid for the year 2019 for the submission of HIPAA-covered transactions.

ICD-10: T46.5X5
Short Description:Adverse effect of other antihypertensive drugs
Long Description:Adverse effect of other antihypertensive drugs

Consider the following ICD-10 codes with a higher level of specificity:

  • T46.5X5A - Adverse effect of other antihypertensive drugs, initial encounter
  • T46.5X5D - Adverse effect of other antihypertensive drugs, subsequent encounter
  • T46.5X5S - Adverse effect of other antihypertensive drugs, sequela

Replaced Code

This code was replaced in the 2019 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2018. This code was replaced for the FY 2019 (October 1, 2018 - September 30, 2019).

  • K59.03 - Drug induced constipation

Code Classification

  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Agents primarily affecting the cardiovascular system (T46)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (first year ICD-10-CM implemented into the HIPAA mandated code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019

Information for Medical Professionals

Diagnostic Related Groups

The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC). The diagnosis code T46.5X5 is grouped in the following groups for version MS-DRG V36.0 applicable from 10/01/2018 through 09/30/2019.

  • 922 - OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITH MCC
  • 923 - OTHER INJURY, POISONING AND TOXIC EFFECT DIAGNOSES WITHOUT MCC
  • 949 - AFTERCARE WITH CC/MCC
  • 950 - AFTERCARE WITHOUT CC/MCC

Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adrenergic neurone blocking drug adverse reaction
  • Adrenergic neurone blocking drug adverse reaction
  • Adrenergic neurone blocking drug adverse reaction
  • Adverse reaction caused by azilsartan
  • Adverse reaction caused by candesartan
  • Adverse reaction caused by eprosartan
  • Adverse reaction caused by irbesartan
  • Adverse reaction caused by olmesartan
  • Adverse reaction caused by telmisartan
  • Adverse reaction caused by valsartan
  • Adverse reaction to reserpine
  • Angiotensin II receptor antagonist adverse reaction
  • Antihypertensive adverse reaction
  • Bethanidine adverse reaction
  • Central alpha-adrenoceptor agonist adverse reaction
  • Central alpha-adrenoceptor agonist adverse reaction
  • Central alpha-adrenoceptor agonist adverse reaction
  • Cirrhosis of liver caused by methyldopa
  • Clonidine adverse reaction
  • Debrisoquine adverse reaction
  • Diazoxide adverse reaction
  • Dihydroergotamine mesylate adverse reaction
  • Drug-induced cirrhosis of liver
  • Drug-induced lupus erythematosus
  • Drug-induced lupus erythematosus due to hydralazine
  • Drug-induced pericarditis
  • Ergoline drug adverse reaction
  • Ergot alkaloid adverse reaction
  • Guanethidine adverse reaction
  • Hydralazine adverse reaction
  • Hydralazine-induced pericarditis
  • Indapamide adverse reaction
  • Lacidipine adverse reaction
  • Lofexidine adverse reaction
  • Methyldopa adverse reaction
  • Methyldopa and diuretic adverse reaction
  • Metirosine adverse reaction
  • Rauwolfia antihypertensive adverse reaction
  • Sodium nitroprusside adverse reaction
  • Sulfonamide diuretic adverse reaction
  • Vasoconstrictor adverse reaction
  • Vasodilator adverse reaction

Table of Drugs and Chemicals

The code T46.5X5 is included in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. Use as many codes as necessary to describe all reported drugs, medicinal or chemical substances.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
self-harm
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AldometT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
AlkavervirT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
AlseroxylonT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
AmiquinsinT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
Antihypertensive drug NECT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
ApresolineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
Benzapril hydrochlorideT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
BetanidineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
BethanidineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
BudralazineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
CadralazineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
ClonidineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
Cryptenamine (tannates)T46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
DebrisoquineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
DeserpidineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
DiazoxideT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
DihydralazineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
DihydrazineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
DihydroergotamineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
EndralazineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
ErgotamineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
GuanabenzT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
GuanaclineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
GuanadrelT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
GuanethidineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
GuanfacineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
GuanochlorT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
GuanoclorT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
GuanoctineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
GuanoxabenzT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
GuanoxanT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
HarmonylT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
HydralazineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
Hypotensive NECT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
IndapamideT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
LacidipineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
MethoserpidineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
MethyldopaT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
MethyldopateT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
MethysergideT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
MetirosineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
ModerilT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
NitroprussideT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
PargylineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
PinacidilT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
Protoveratrine (s) (A) (B)T46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
RaudixinT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
RautensinT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
RautinaT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
RautotalT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
RauwiloidT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
RauwoldinT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
Rauwolfia (alkaloids)T46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
RescinnamineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
Reserpin (e)T46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
SandrilT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
SaralasinT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
SerpasilT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
SingoserpT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
SyrosingopineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
TeprotideT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
TodralazineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
TolonidineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
UrapidilT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6
VeratrineT46.5X1T46.5X2T46.5X3T46.5X4T46.5X5T46.5X6

Information for Patients


Drug Reactions

Also called: Side effects

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as ginkgo and blood thinners
  • Drugs and diseases, such as aspirin and peptic ulcers

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.

  • Angioedema (Medical Encyclopedia)
  • Drug allergies (Medical Encyclopedia)
  • Drug-induced diarrhea (Medical Encyclopedia)
  • Drug-induced tremor (Medical Encyclopedia)
  • Taking multiple medicines safely (Medical Encyclopedia)

[Learn More]

ICD-10 Footnotes

General Equivalence Map Definitions
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.