2022 ICD-10-CM Code T45.3X4

Poisoning by enzymes, undetermined

Version 2021

Not Valid for Submission

ICD-10:T45.3X4
Short Description:Poisoning by enzymes, undetermined
Long Description:Poisoning by enzymes, undetermined

Code Classification

  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Primarily systemic and hematological agents, NEC (T45)

T45.3X4 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of poisoning by enzymes, undetermined. The code is not specific and is NOT valid for the year 2022 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

The ICD-10-CM code T45.3X4 might also be used to specify conditions or terms like penicillinase poisoning of undetermined intent, poisoning by penicillinase, poisoning by streptodornase or streptodornase poisoning of undetermined intent.

Coding Guidelines

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Primarily systemic and hematological agents, NEC (T45). Use the following options for the aplicable episode of care:

Specific Coding for Poisoning by enzymes, undetermined

Non-specific codes like T45.3X4 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for poisoning by enzymes, undetermined:

  • BILLABLE CODE - Use T45.3X4A for initial encounter
  • BILLABLE CODE - Use T45.3X4D for subsequent encounter
  • BILLABLE CODE - Use T45.3X4S for sequela

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

Table of Drugs and Chemicals

The code T45.3X4 is included in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents. According to ICD-10 coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
self-harm
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AlgluceraseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
AlidaseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
BrinaseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
BromelainsT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
CatalaseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
ChymarT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Chymar
  »ophthalmic preparation
T45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
ChymopapainT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
ChymotrypsinT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Chymotrypsin
  »ophthalmic preparation
T45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
CocarboxylaseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Deoxyribonuclease (pancreatic)T45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
DiffusinT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
EnzodaseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Enzyme NECT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Enzyme NEC
  »depolymerizing
T45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Enzyme NEC
  »fibrolytic
T45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Enzyme NEC
  »gastric
T45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Enzyme NEC
  »intestinal
T45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Enzyme NEC
  »local action
T45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Enzyme NEC
  »proteolytic
T45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
Enzyme NEC
  »thrombolytic
T45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
HyaluronidaseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
HyazymeT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
PenicillinaseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
PronaseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
SerrapeptaseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
StreptodornaseT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
SutilainsT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6
TrypsinT45.3X1T45.3X2T45.3X3T45.3X4T45.3X5T45.3X6

Information for Patients


Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include

The effects of poisoning range from short-term illness to brain damage, coma, and death. To prevent poisoning it is important to use and store products exactly as their labels say. Keep dangerous products where children can't get to them. Treatment for poisoning depends on the type of poison. If you suspect someone has been poisoned, call your local poison control center at 1-800-222-1222 right away.


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Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)