ICD-10 Code T44.3X5

Adverse effect of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics

Version 2019 Replaced Code Non-Billable Code Adverse Effect

Not Valid for Submission

T44.3X5 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics. The code is NOT valid for the year 2020 for the submission of HIPAA-covered transactions.

ICD-10: T44.3X5
Short Description:Adverse effect of other parasympatholytics and spasmolytics
Long Description:Adverse effect of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics

Consider the following ICD-10 codes with a higher level of specificity:

  • T44.3X5A - Adverse effect of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, initial encounter
  • T44.3X5D - Adverse effect of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, subsequent encounter
  • T44.3X5S - Adverse effect of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, sequela

Replaced Code

This code was replaced in the 2020 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2019. This code was replaced for the FY 2020 (October 1, 2019 - September 30, 2020).

  • K59.03 - Drug induced constipation

Code Classification

  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Drugs primarily affecting the autonomic nervous system (T44)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (first year ICD-10-CM implemented into the HIPAA mandated code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Medical Professionals

Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to adiphenine
  • Adverse reaction to parasympatholytic and spasmolytic
  • Adverse reaction to smooth muscle relaxant
  • Alverine adverse reaction
  • Anticholinergic adverse reaction
  • Antimuscarinic adverse reaction
  • Antispasmodic adverse reaction
  • Antispasmodic adverse reaction
  • Antispasmodic adverse reaction
  • Antispasmodic adverse reaction
  • Antispasmodic adverse reaction
  • Antispasmodic adverse reaction
  • Antispasmodic adverse reaction
  • Antispasmodic adverse reaction
  • Atropine adverse reaction
  • Belladonna alkaloids adverse reaction
  • Biperiden adverse reaction
  • Cyclopentolate adverse reaction
  • Dicycloverine adverse reaction
  • Emepronium bromide adverse reaction
  • Flavoxate adverse reaction
  • Glycopyrronium adverse reaction
  • Homatropine adverse reaction
  • Hyoscine adverse reaction
  • Hyoscine butylbromide adverse reaction
  • Hyoscine hydrobromide adverse reaction
  • Mebeverine adverse reaction
  • Mepenzolate adverse reaction
  • Methixene adverse reaction
  • Oxybutynin adverse reaction
  • Papaverine adverse reaction
  • Phosphodiesterase inhibitor adverse reaction
  • Pipenzolate adverse reaction
  • Piperidolate hydrochloride adverse reaction
  • Poldine adverse reaction
  • Procyclidine adverse reaction
  • Propantheline adverse reaction
  • Trihexyphenidyl adverse reaction
  • Tropicamide adverse reaction

Table of Drugs and Chemicals

The code T44.3X5 is included in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. Use as many codes as necessary to describe all reported drugs, medicinal or chemical substances.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
self-harm
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AdiphenineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
AlverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Ambutonium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
AminopentamideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
AmprotropineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
AniscoropineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Anisotropine methyl-bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Anticholinergic NECT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Antimuscarinic NECT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
ArtaneT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
AtropineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Atropine
  »derivative
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Atropine
  »methonitrate
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Belladonna [See Also: Nightshade]T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Belladonna [See Also: Nightshade]
  »alkaloids
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Belladonna [See Also: Nightshade]
  »extract
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Belladonna [See Also: Nightshade]
  »herb
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
BenactyzineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
BenaprizineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
BenzhexolT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Benzilonium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
BenztropineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Benztropine
  »anticholinergic
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Benztropine
  »antiparkinson
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Bevonium metilsulfateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
BiperidenT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
BornaprineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
ButethamateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Butropium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
CamylofinT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
CaramiphenT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Carpronium chlorideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
ChlorbenzoxamineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Cimetropium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Clidinium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
ClorotepineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
CogentinT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
CyclodrineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
CyclopentolateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
CycrimineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
DexetimideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Dibutoline sulfateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
DicyclomineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
DicycloverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
DiisopromineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
DiphemanilT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Diphemanil
  »metilsulfate
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
DrotaverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
DuboisineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
DyphyllineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Emepronium (salts)T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Emepronium (salts)
  »bromide
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
EthaverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
EthopropazineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
EtomidolineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
EtybenzatropineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
EuphthalmineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Extrapyramidal antagonist NECT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
FenoverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
FlavoxateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
FlopropioneT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
GefarnateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
GlycopyrrolateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
GlycopyrroniumT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Glycopyrronium
  »bromide
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Hexasonium iodideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
HexocycliumT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Hexocyclium
  »metilsulfate
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
HomatropineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Homatropine
  »methylbromide
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
HyoscineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
HyoscyamineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
HyoscyamusT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Hyoscyamus
  »dry extract
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
IsomethepteneT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
IsopropamideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Isopropamide
  »iodide
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
LevsinT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
MebeverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
MeladrazineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
MepenzolateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Mepenzolate
  »bromide
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
MepiperphenidolT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
MethanthelineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Methanthelinium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
MethixeneT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Methscopolamine bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Methylatropine nitrateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Methylbenactyzium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
MetixeneT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
MilverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
MoxaverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
MydriacylT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Octatropine methyl-bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Otilonium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Oxapium iodideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
OxybutyninT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
OxyphencyclimineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Oxyphenonium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
PapaverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Parasympatholytic NECT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Penthienate bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
PhenglutarimideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Pinaverium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Pipenzolate bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
PiperidolateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
PipethanateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Poldine metilsulfateT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
PramiverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
PridinolT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Prifinium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Pro-BanthineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
ProcyclidineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
ProfenamineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
ProfenilT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
PropanthelineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Propantheline
  »bromide
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
RociverineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
ScopolamineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Scopolia extractT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Smooth muscle relaxantT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
SpacolineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
SpasmolyticT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Spasmolytic
  »anticholinergics
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Spasmolytic
  »autonomic
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Spasmolytic
  »bronchial NEC
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Spasmolytic
  »quaternary ammonium
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Spasmolytic
  »skeletal muscle NEC
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
SulmetozineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
ThiphenamilT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TiemoniumT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Tiemonium
  »iodide
T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TifenamilT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TigloidineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Timepidium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Tiquizium bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TolperisoneT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
ToquizineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TrasentineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TriampyzineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Tricyclamol chlorideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Tridihexethyl iodideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TrihexyphenidylT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TrimebutineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Trimeprazine (tartrate)T44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TriperidenT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TrithiozineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TritiozineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TropacineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TropatepineT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
TropicamideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Trospium chlorideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6
Valethamate bromideT44.3X1T44.3X2T44.3X3T44.3X4T44.3X5T44.3X6

Information for Patients


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as ginkgo and blood thinners
  • Drugs and diseases, such as aspirin and peptic ulcers

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.


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ICD-10 Footnotes

General Equivalence Map Definitions
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.