2024 ICD-10-CM Diagnosis Code T44.3X5
Adverse effect of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics
- ICD-10-CM Code:
- T44.3X5
- ICD-10 Code for:
- Adverse effect of other parasympatholytics and spasmolytics
- Is Billable?
- Not Valid for Submission
- Code Navigator:
T44.3X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.
Specific Coding Applicable to Adverse effect of other parasympatholytics and spasmolytics
Non-specific codes like T44.3X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of other parasympatholytics and spasmolytics:
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Adverse reaction to adiphenine
- Adverse reaction to piperidolate
- Adverse reaction to smooth muscle relaxant
- Alverine adverse reaction
- Anticholinergic adverse reaction
- Antimuscarinic adverse reaction
- Atropine adverse reaction
- Belladonna alkaloids adverse reaction
- Biperiden adverse reaction
- Cyclopentolate adverse reaction
- Dicycloverine adverse reaction
- Emepronium bromide adverse reaction
- Flavoxate adverse reaction
- Glycopyrronium adverse reaction
- Homatropine adverse reaction
- Hyoscine adverse reaction
- Hyoscine butylbromide adverse reaction
- Hyoscine hydrobromide adverse reaction
- Mebeverine adverse reaction
- Mepenzolate adverse reaction
- Methixene adverse reaction
- Opium alkaloid adverse reaction
- Oxybutynin adverse reaction
- Papaverine adverse reaction
- Phosphodiesterase inhibitor adverse reaction
- Pipenzolate adverse reaction
- Poldine adverse reaction
- Procyclidine adverse reaction
- Propantheline adverse reaction
- Trihexyphenidyl adverse reaction
- Tropicamide adverse reaction
Clinical Information
Atropine
an alkaloid, originally from atropa belladonna, but found in other plants, mainly solanaceae. hyoscyamine is the 3(s)-endo isomer of atropine.Atropine Derivatives
analogs and derivatives of atropine.Hyoscyamine
the 3(s)-endo isomer of atropine.Benactyzine
a centrally acting muscarinic antagonist. benactyzine has been used in the treatment of depression and is used in research to investigate the role of cholinergic systems on behavior.Benztropine
a centrally active muscarinic antagonist that has been used in the symptomatic treatment of parkinson disease. benztropine also inhibits the uptake of dopamine.Biperiden
a muscarinic antagonist that has effects in both the central and peripheral nervous systems. it has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. it has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.Cyclopentolate
a parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.Dexetimide
a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. benzetimide is the (-)-enantimorph of dexetimide.Dicyclomine
a muscarinic antagonist used as an antispasmodic and in urinary incontinence. it has little effect on glandular secretion or the cardiovascular system. it does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.Dyphylline
a theophylline derivative with broncho- and vasodilator properties. it is used in the treatment of asthma, cardiac dyspnea, and bronchitis.Flavoxate
a drug that has been used in various urinary syndromes and as an antispasmodic. its therapeutic usefulness and its mechanism of action are not clear. it may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist.Gefarnate
a water insoluble terpene fatty acid used in the treatment of gastrointestinal ulcers; it facilitates the healing and function of mucosal tissue.Glycopyrrolate
a muscarinic antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics.Hyoscyamus
a plant genus of the family solanaceae which contains tropanes.Methantheline
a quaternary ammonium compound that acts as an antimuscarinic agent. it has been used in the treatment of peptic ulcer, in gastrointestinal disorders associated with smooth muscle spasm, and in the management of urinary incontinence, and may also be used for the treatment of hyperhidrosis.Papaverine
an alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. it is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. the mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.Procyclidine
a muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.Propantheline
a muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. at high doses it has nicotinic effects resulting in neuromuscular blocking.Butylscopolammonium Bromide
antimuscarinic quaternary ammonium derivative of scopolamine used to treat cramps in gastrointestinal, urinary, uterine, and biliary tracts, and to facilitate radiologic visualization of the gastrointestinal tract.N-Methylscopolamine
a muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors.Scopolamine
an alkaloid from solanaceae, especially datura and scopolia. scopolamine and its quaternary derivatives act as antimuscarinics like atropine, but may have more central nervous system effects. its many uses include an anesthetic premedication, the treatment of urinary incontinence and motion sickness, an antispasmodic, and a mydriatic and cycloplegic.Scopolamine Derivatives
analogs or derivatives of scopolamine.Tolperisone
a centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. (from martindale, the extra pharmacopoeia, 30th ed, p1211)Trihexyphenidyl
one of the centrally acting muscarinic antagonists used for treatment of parkinsonian disorders and drug-induced extrapyramidal movement disorders and as an antispasmodic.Trimebutine
proposed spasmolytic with possible local anesthetic action used in gastrointestinal disorders.Tropicamide
one of the muscarinic antagonists with pharmacologic action similar to atropine and used mainly as an ophthalmic parasympatholytic or mydriatic.
Coding Guidelines
When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (T44). Use the following options for the aplicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Table of Drugs and Chemicals
The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.
According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.
Patient Education
Drug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
What is a drug interaction?
A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:
- Two drugs, such as aspirin and blood thinners
- Drugs and food, such as statins and grapefruit
- Drugs and supplements, such as gingko and blood thinners
- Drugs and medical conditions, such as aspirin and peptic ulcers
Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.
What are side effects?
Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.
What are drug allergies?
Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.
How can I stay safe when taking medicines?
When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.
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Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.