2024 ICD-10-CM Diagnosis Code T41.5X5

Adverse effect of therapeutic gases

ICD-10-CM Code:
T41.5X5
ICD-10 Code for:
Adverse effect of therapeutic gases
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases
        (T41)

T41.5X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of therapeutic gases. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of therapeutic gases

Non-specific codes like T41.5X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of therapeutic gases:

  • Use T41.5X5A for initial encounter - BILLABLE CODE

  • Use T41.5X5D for subsequent encounter - BILLABLE CODE

  • Use T41.5X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Anemia due to oxygen
  • Anemia due to oxygen
  • Chemical-induced pulmonary edema
  • Hemolytic anemia due to hyperbaric oxygen
  • Oxygen-induced pulmonary edema

Clinical Information

  • 3-Hydroxyanthranilate 3,4-Dioxygenase

    an enzyme that catalyzes the conversion of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. it was formerly characterized as ec 1.13.1.6.
  • Biological Oxygen Demand Analysis

    testing for the amount of biodegradable organic material in a water sample by measuring the quantity of oxygen consumed by biodegradation of those materials over a specific time period.
  • Blood Gas Monitoring, Transcutaneous

    the noninvasive measurement or determination of the partial pressure (tension) of oxygen and/or carbon dioxide locally in the capillaries of a tissue by the application to the skin of a special set of electrodes. these electrodes contain photoelectric sensors capable of picking up the specific wavelengths of radiation emitted by oxygenated versus reduced hemoglobin.
  • Extracorporeal Membrane Oxygenation

    application of a life support system that circulates the blood through an oxygenating system, which may consist of a pump, a membrane oxygenator, and a heat exchanger. examples of its use are to assist victims of smoke inhalation injury; respiratory failure; and cardiac failure.
  • Heme Oxygenase (Decyclizing)

    a mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced nadph. the enzyme is induced by metals, particularly cobalt.
  • Heme Oxygenase-1

    a ubiquitous stress-responsive enzyme that catalyzes the oxidative cleavage of heme to yield iron; carbon monoxide; and biliverdin.
  • Homogentisate 1,2-Dioxygenase

    a mononuclear fe(ii)-dependent oxygenase, this enzyme catalyzes the conversion of homogentisate to 4-maleylacetoacetate, the third step in the pathway for the catabolism of tyrosine. deficiency in the enzyme causes alkaptonuria, an autosomal recessive disorder, characterized by homogentisic aciduria, ochronosis and arthritis. this enzyme was formerly characterized as ec 1.13.1.5 and ec 1.99.2.5.
  • Hyperbaric Oxygenation

    the therapeutic intermittent administration of oxygen in a chamber at greater than sea-level atmospheric pressures (three atmospheres). it is considered effective treatment for air and gas embolisms, smoke inhalation, acute carbon monoxide poisoning, caisson disease, clostridial gangrene, etc. (from segen, dictionary of modern medicine, 1992). the list of treatment modalities includes stroke.
  • Hypoxia

    sub-optimal oxygen levels in the ambient air of living organisms.
  • Inositol Oxygenase

    a non-heme iron enzyme that catalyzes the conversion of myoinositol to d-glucuronic acid. the reaction is the first committed step in myoinositol catabolic pathway. this enzyme was formerly characterized as ec 1.13.1.11 and 1.99.2.6.
  • Mixed Function Oxygenases

    widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. they are also known as monooxygenases or hydroxylases. these reactions require two substrates as reductants for each of the two oxygen atoms. there are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (coenzymes) required in the mixed-function oxidation.
  • Oxygen

    an element with atomic symbol o, atomic number 8, and atomic weight [15.99903; 15.99977]. it is the most abundant element on earth and essential for respiration.
  • Oxygen Compounds

    inorganic compounds that contain oxygen as an integral part of the molecule.
  • Oxygen Consumption

    the rate at which oxygen is used by a tissue; microliters of oxygen stpd used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (stedman, 25th ed, p346)
  • Oxygen Inhalation Therapy

    inhalation of oxygen aimed at restoring toward normal any pathophysiologic alterations of gas exchange in the cardiopulmonary system, as by the use of a respirator, nasal catheter, tent, chamber, or mask. (from dorland, 27th ed & stedman, 25th ed)
  • Oxygen Isotopes

    stable oxygen atoms that have the same atomic number as the element oxygen, but differ in atomic weight. o-17 and 18 are stable oxygen isotopes.
  • Oxygen Radical Absorbance Capacity

    a measure of the ability of a substance, such as a food, to quench oxygen free radicals in vitro.
  • Oxygen Radioisotopes

    unstable isotopes of oxygen that decay or disintegrate emitting radiation. o atoms with atomic weights 13, 14, 15, 19, and 20 are radioactive oxygen isotopes.
  • Oxygen Saturation

    extent to which hemoglobin is saturated with oxygen typically as measured in arterial blood. it can be measured by various methods (e.g., pulse oxymeter, blood gas analysis). a low blood oxygen saturation level indicates a condition called hypoxemia.
  • Oxygenases

    oxidases that specifically introduce dioxygen-derived oxygen atoms into a variety of organic molecules.
  • Oxygenators

    devices which mechanically oxygenate venous blood extracorporeally. they are used in combination with one or more pumps for maintaining circulation during open heart surgery and for assisting the circulation in patients seriously ill with some cardiac and pulmonary disorders. (umdns, 1999)
  • Oxygenators, Membrane

    devices in which blood and oxygen are separated by a semipermeable membrane, generally of teflon or polypropylene, across which gas exchange occurs. the membrane may be arranged as a series of parallel plates or as a number of hollow fibers; in the latter arrangement, the blood may flow inside the fibers, which are surrounded by gas, or the blood may flow outside the fibers and the gas inside the fibers. (dorland, 28th ed)
  • Photosystem II Protein Complex

    a large multisubunit protein complex found in the thylakoid membrane. it uses light energy derived from light-harvesting protein complexes to catalyze the splitting of water into dioxygen and of reducing equivalents of hydrogen.
  • Reactive Oxygen Species

    molecules or ions formed by the incomplete one-electron reduction of oxygen. these reactive oxygen intermediates include singlet oxygen; superoxides; peroxides; hydroxyl radical; and hypochlorous acid. they contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to nucleic acids; proteins; and lipids.
  • Singlet Oxygen

    an excited state of molecular oxygen generated photochemically or chemically. singlet oxygen reacts with a variety of biological molecules such as nucleic acids; proteins; and lipids; causing oxidative damages.
  • Tryptophan Oxygenase

    a dioxygenase with specificity for the oxidation of the indoleamine ring of tryptophan. it is a liver-specific enzyme that is the first and rate limiting enzyme in the kynurenine pathway of tryptophan catabolism.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases (T41). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
OxygenT41.5X1T41.5X2T41.5X3T41.5X4T41.5X5T41.5X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.