ICD-10-CM Code T39.015

Adverse effect of aspirin

Version 2021 Replaced Code Non-Billable Code Adverse Effect

Not Valid for Submission

T39.015 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of aspirin. The code is NOT valid for the year 2021 for the submission of HIPAA-covered transactions. The ICD-10-CM code T39.015 might also be used to specify conditions or terms like adverse reaction to salicylate, adverse reaction to salicylate, adverse reaction to salicylate, adverse reaction to salicylate, adverse reaction to salicylate, aspirin adverse reaction, etc

Short Description:Adverse effect of aspirin
Long Description:Adverse effect of aspirin

Consider the following ICD-10 codes with a higher level of specificity:

Replaced Code

This code was replaced in the 2021 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2020. This code was replaced for the FY 2021 (October 1, 2020 - September 30, 2021).

  • K59.03 - Drug induced constipation


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to salicylate
  • Adverse reaction to salicylate
  • Adverse reaction to salicylate
  • Adverse reaction to salicylate
  • Adverse reaction to salicylate
  • Aspirin adverse reaction
  • Aspirin adverse reaction
  • Aspirin adverse reaction
  • Aspirin adverse reaction
  • Aspirin adverse reaction
  • Aspirin burn of oral mucosa
  • Aspirin exacerbated respiratory disease
  • Aspirin-induced anaphylactoid reaction
  • Aspirin-induced angioedema-urticaria
  • Aspirin-induced asthma
  • Aspirin-induced asthma
  • Chemical-induced asthma
  • Chemical-induced asthma
  • Drug-induced anaphylactoid reaction
  • Drug-induced asthma
  • Drug-induced asthma
  • Drug-induced mucositis
  • Esophageal ulcer due to aspirin
  • Non-allergic drug hypersensitivity disorder
  • Non-allergic drug hypersensitivity disorder
  • NSAID-induced anaphylactoid reaction
  • NSAID-induced angioedema-urticaria
  • Stomatitis medicamentosa
  • Ulcer of esophagus due to ingestion of medicines
  • Urticaria due to salicylate
  • Urticaria medicamentosa

Code Classification

  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Nonopioid analgesics, antipyretics and antirheumatics (T39)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Table of Drugs and Chemicals

The code T39.015 is included in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. Use as many codes as necessary to describe all reported drugs, medicinal or chemical substances.

Substance Poisoning
Acetylsalicylic acid (salts)T39.011T39.012T39.013T39.014T39.015T39.016
Acetylsalicylic acid (salts)
  »enteric coated
Aspirin (aluminum) (soluble)T39.011T39.012T39.013T39.014T39.015T39.016

Information for Patients

Drug Reactions

Also called: Side effects

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as ginkgo and blood thinners
  • Drugs and diseases, such as aspirin and peptic ulcers

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.

  • Angioedema (Medical Encyclopedia)
  • Drug allergies (Medical Encyclopedia)
  • Drug-induced diarrhea (Medical Encyclopedia)
  • Drug-induced tremor (Medical Encyclopedia)
  • Taking multiple medicines safely (Medical Encyclopedia)

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