ICD-10 Code T38.5X5

Adverse effect of other estrogens and progestogens

Version 2019 Replaced Code Non-Billable Code Adverse Effect

Not Valid for Submission

T38.5X5 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of other estrogens and progestogens. The code is NOT valid for the year 2020 for the submission of HIPAA-covered transactions.

ICD-10: T38.5X5
Short Description:Adverse effect of other estrogens and progestogens
Long Description:Adverse effect of other estrogens and progestogens

Consider the following ICD-10 codes with a higher level of specificity:

  • T38.5X5A - Adverse effect of other estrogens and progestogens, initial encounter
  • T38.5X5D - Adverse effect of other estrogens and progestogens, subsequent encounter
  • T38.5X5S - Adverse effect of other estrogens and progestogens, sequela

Replaced Code

This code was replaced in the 2020 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2019. This code was replaced for the FY 2020 (October 1, 2019 - September 30, 2020).

  • K59.03 - Drug induced constipation

Code Classification

  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Hormones and their synthetic substitutes and antag, NEC (T38)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (first year ICD-10-CM implemented into the HIPAA mandated code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Medical Professionals

Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to ovarian hormone
  • Allylestrenol adverse reaction
  • Anti-androgens adverse reaction
  • Clomiphene adverse reaction
  • Conjugated estrogens adverse reaction
  • Cyproterone acetate and ethinylestradiol adverse reaction
  • Cyproterone adverse reaction
  • Dienestrol adverse reaction
  • Dydrogesterone adverse reaction
  • Endometriosis of the spermatic cord following estrogen therapy
  • Estradiol adverse reaction
  • Estradiol implant adverse reaction
  • Estriol adverse reaction
  • Estrogen adverse reaction
  • Estrogen and progestogen preparation adverse reaction
  • Estrogen antagonist adverse reaction
  • Ethinylestradiol adverse reaction
  • Ethinylestradiol adverse reaction
  • Fosfestrol adverse reaction
  • Gestrinone adverse reaction
  • Gestronol adverse reaction
  • HRT side-effects
  • Hydroxyprogesterone adverse reaction
  • Medroxyprogesterone adverse reaction
  • Megestrol adverse reaction
  • Menopause monitoring status
  • Mestranol adverse reaction
  • Oral estradiol adverse reaction
  • Piperazine estrone sulfate adverse reaction
  • Polyestradiol phosphate adverse reaction
  • Progesterone adverse reaction
  • Progestogen adverse reaction
  • Quinestradol adverse reaction
  • Quinestrol adverse reaction
  • Stilbestrol adverse reaction
  • Stilbestrol-related vaginal adenosis
  • Topical estradiol adverse reaction
  • Vaginal adenosis

Table of Drugs and Chemicals

The code T38.5X5 is included in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. Use as many codes as necessary to describe all reported drugs, medicinal or chemical substances.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
self-harm
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AllylestrenolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Anhydrohydroxy-progesteroneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
ChlormadinoneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
ChlorotrianiseneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
ChlortrianiseneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
ClomifeneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
ClomipheneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Conjugated estrogenic substancesT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DelalutinT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DemegestoneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DesogestrelT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DiaethylstilboestrolumT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DienestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DienoestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DiethylstilbestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DiethylstilboestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DimestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DimethisteroneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
DydrogesteroneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
EpiestriolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
EpimestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
EstradiolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Estradiol
  »with testosterone
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Estradiol
  »benzoate
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
EstriolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
EstrogenT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Estrogen
  »with progesterone
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Estrogen
  »conjugated
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
EstroneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
EstropipateT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Ethinylestradiol, ethinyloestradiolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Ethinylestradiol, ethinyloestradiol
  »with
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Ethinylestradiol, ethinyloestradiol
  »with
    »levonorgestrel
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Ethinylestradiol, ethinyloestradiol
  »with
    »norethisterone
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
EthisteroneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
FosfestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Gestonorone caproateT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
HexestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
HexoestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
HydroxyestroneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
HydroxyprogesteroneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Hydroxyprogesterone
  »caproate
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
IsopregnenoneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Lipo-LutinT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
LutocylolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
LutromoneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
MedrogestoneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Medroxyprogesterone acetate (depot)T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
MegestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
MestranolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
MethallenestrilT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
MethallenoestrilT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
MethylestrenoloneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
NomegestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
NoretynodrelT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
NormethandroneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
OestradiolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
OestriolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
OestrogenT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
OestroneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
OvarianT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Ovarian
  »hormone
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Ovarian
  »stimulant
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
OxendoloneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Polyestradiol phosphateT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Polyoestradiol phosphateT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
PregnandiolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
PregneninoloneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
PremarinT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
ProgesteroneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
ProgestinT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Progestin
  »oral contraceptive
T38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
Progestogen NECT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
ProgestoneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
ProlutonT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
PromegestoneT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
ProveraT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
QuinestradiolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
QuinestradolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
QuinestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
StilbestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
StilboestrolT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6
TaceT38.5X1T38.5X2T38.5X3T38.5X4T38.5X5T38.5X6

Information for Patients


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as ginkgo and blood thinners
  • Drugs and diseases, such as aspirin and peptic ulcers

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.


[Learn More]

ICD-10 Footnotes

General Equivalence Map Definitions
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.