2024 ICD-10-CM Diagnosis Code T38.5X3A
Poisoning by other estrogens and progestogens, assault, initial encounter
- ICD-10-CM Code:
- T38.5X3A
- ICD-10 Code for:
- Poisoning by oth estrogens and progestogens, assault, init
- Is Billable?
- Yes - Valid for Submission
- Chronic Condition Indicator: [1]
- Not chronic
- Code Navigator:
T38.5X3A is a billable diagnosis code used to specify a medical diagnosis of poisoning by other estrogens and progestogens, assault, initial encounter. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.
T38.5X3A is an initial encounter code, includes a 7th character and should be used while the patient is receiving active treatment for a condition like poisoning by other estrogens and progestogens assault. According to ICD-10-CM Guidelines an "initial encounter" doesn't necessarily means "initial visit". The 7th character should be used when the patient is undergoing active treatment regardless if new or different providers saw the patient over the course of a treatment. The appropriate 7th character codes should also be used even if the patient delayed seeking treatment for a condition.
Clinical Classification
Clinical Category | CCSR Category Code | Inpatient Default CCSR | Outpatient Default CCSR |
---|---|---|---|
External cause codes: intent of injury, assault | EXT022 | N - Not default inpatient assignment for principal diagnosis or first-listed diagnosis. | N - Not default outpatient assignment for principal diagnosis or first-listed diagnosis. |
External cause codes: poisoning by drug | EXT014 | N - Not default inpatient assignment for principal diagnosis or first-listed diagnosis. | N - Not default outpatient assignment for principal diagnosis or first-listed diagnosis. |
Poisoning by drugs, initial encounter | INJ022 | Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis. | Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis. |
Clinical Information
Allylestrenol
a synthetic steroid with progestational activity.Chlorotrianisene
a powerful synthetic, non-steroidal estrogen.Clomiphene
a triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. note that enclomiphene and zuclomiphene are the (e) and (z) isomers of clomiphene respectively.Desogestrel
a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents (oral contraceptives, combined).Dienestrol
a synthetic, non-steroidal estrogen structurally related to stilbestrol. it is used, usually as the cream, in the treatment of menopausal and postmenopausal symptoms.Diethylstilbestrol
a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. it was also used formerly as a growth promoter in animals. according to the fourth annual report on carcinogens (ntp 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (merck, 11th ed)Dimethisterone
a synthetic progestational hormone without significant estrogenic or androgenic properties. it was formerly used as the progestational component in sequential oral contraceptive agents .Dydrogesterone
a synthetic progestational hormone with no androgenic or estrogenic properties. unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.Epimestrol
a synthetic steroid with estrogenic activity.Estradiol
the 17-beta-isomer of estradiol, an aromatized c18 steroid with hydroxyl group at 3-beta- and 17-beta-position. estradiol-17-beta is the most potent form of mammalian estrogenic steroids.Estradiol Congeners
steroidal compounds related to estradiol, the major mammalian female sex hormone. estradiol congeners include important estradiol precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with estrogenic activities.Estradiol Dehydrogenases
enzymes that catalyze the oxidation of estradiol at the 17-hydroxyl group in the presence of nad+ or nadp+ to yield estrone and nadh or nadph. the 17-hydroxyl group can be in the alpha- or beta-configuration. ec 1.1.1.62Estrogen Antagonists
compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds.Estrogen Receptor alpha
one of the estrogen receptors that has marked affinity for estradiol. its expression and function differs from, and in some ways opposes, estrogen receptor beta.Estrogen Receptor Antagonists
compounds and drugs that bind to and block or inhibit the activation of estrogen receptors.Ethinyl Estradiol
a semisynthetic alkylated estradiol with a 17-alpha-ethinyl substitution. it has high estrogenic potency when administered orally, and is often used as the estrogenic component in oral contraceptives.Ethinyl Estradiol-Norgestrel Combination
ethinyl estradiol and norgestrel given in fixed proportions.Receptors, Estradiol
cytoplasmic proteins that bind estradiol, migrate to the nucleus, and regulate dna transcription.Steroid 16-alpha-Hydroxylase
a liver microsomal cytochrome p450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and nadph-ferrihemoprotein reductase. this enzyme is encoded by a number of genes from several cyp2 subfamilies.Estriol
a hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at c3, 16-alpha, and 17-beta position. estriol is a major urinary estrogen. during pregnancy, a large amount of estriol is produced by the placenta. isomers with inversion of the hydroxyl group or groups are called epiestriol.Estrone
an aromatized c18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. it is converted from androstenedione directly, or from testosterone via estradiol. in humans, it is produced primarily by the cyclic ovaries, placenta, and the adipose tissue of men and postmenopausal women.Glucuronosyltransferase
a family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. they function as drug-metabolizing enzymes that catalyze the conjugation of udpglucuronic acid to a variety of endogenous and exogenous compounds. ec 2.4.1.17.Steryl-Sulfatase
an arylsulfatase with high specificity towards sulfated steroids. defects in this enzyme are the cause of ichthyosis, x-linked.Ethisterone
17 alpha-hydroxypregn-4-en-20-yn-3-one. a synthetic steroid hormone with progestational effects.Gestonorone Caproate
a long-acting potent progestogen structurally related to progesterone. (from martindale, the extra pharmacopoeia, 30th ed, p1185)Hexestrol
a synthetic estrogen that has been used as a hormonal antineoplastic agent.Medrogestone
6,17-dimethylpregna-4,6-diene-3,20-dione. a synthetic progestational hormone with actions similar to those of progesterone. it is used in the treatment of menstrual irregularities and has also been employed in the treatment of prostatic hypertrophy and endometrial carcinoma.Megestrol
a progestational hormone used most commonly as the acetate ester. as the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. it has also been used in the palliative treatment of breast cancer.Megestrol Acetate
megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. it also has anti-androgenic properties. it is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. megestrol acetate has been approved to treat anorexia and cachexia. (from reynolds jef(ed): martindale: the extra pharmacopoeia (electronic version). micromedex, inc, englewood, co, 1995)Mestranol
the 3-methyl ether of ethinyl estradiol. it must be demethylated to be biologically active. it is used as the estrogen component of many combination oral contraceptives.Intrauterine Devices, Medicated
intrauterine devices that release contraceptive agents.Progesterone
the major progestational steroid that is secreted primarily by the corpus luteum and the placenta. progesterone acts on the uterus, the mammary glands and the brain. it is required in embryo implantation; pregnancy maintenance, and the development of mammary tissue for milk production. progesterone, converted from pregnenolone, also serves as an intermediate in the biosynthesis of gonadal steroid hormones and adrenal corticosteroids.Progesterone Congeners
steroidal compounds related to progesterone, the major mammalian progestational hormone. progesterone congeners include important progesterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with progestational activities.Progesterone Reductase
an enzyme that catalyzes the reduction of a 3 beta-hydroxy-delta(5)-steroid to 3-oxo-delta(4)-steroid in the presence of nad. it converts pregnenolone to progesterone and dehydroepiandrosterone to androstenedione. ec 1.1.1.145.Progesterone-Binding Globulin
a glycoprotein migrating as alpha 1-globulin, molecular weight 70,000 to 120,000. the protein, which is present in increased amounts in the plasma during pregnancy, binds mainly progesterone, with other steroids including testosterone competing weakly.Receptors, Progesterone
specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. the cytosol progesterone-receptor complex then associates with the nucleic acids to initiate protein synthesis. there are two kinds of progesterone receptors, a and b. both are induced by estrogen and have short half-lives.Steroid 21-Hydroxylase
an adrenal microsomal cytochrome p450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and nadph-ferrihemoprotein reductase. this enzyme, encoded by cyp21 gene, converts progesterones to precursors of adrenal steroid hormones (corticosterone; hydrocortisone). defects in cyp21 cause congenital adrenal hyperplasia (adrenal hyperplasia, congenital).Promegestone
a synthetic progestin which is useful for the study of progestin distribution and progestin tissue receptors, as it is not bound by transcortin and binds to progesterone receptors with a higher association constant than progesterone.Quinestrol
the 3-cyclopentyl ether of ethinyl estradiol. after gastrointestinal absorption, it is stored in adipose tissue, slowly released, and metabolized principally to the parent compound. it has been used in estrogen replacement therapy. (from ama drug evaluations annual, 1992, p1011)
Coding Guidelines
When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified (T38). Use the following options for the aplicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Convert T38.5X3A to ICD-9-CM
- ICD-9-CM Code: 962.2 - Poisoning-ovarian hormon
Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment. - ICD-9-CM Code: E962.0 - Assault-pois w medic agt
Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.
Table of Drugs and Chemicals
The parent code T38.5X3 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.
According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.
Patient Education
Hormones
Hormones are your body's chemical messengers. They travel in your bloodstream to tissues or organs. They work slowly, over time, and affect many different processes, including:
- Growth and development
- Metabolism - how your body gets energy from the foods you eat
- Sexual function
- Reproduction
- Mood
Endocrine glands, which are special groups of cells, make hormones. The major endocrine glands are the pituitary, pineal, thymus, thyroid, adrenal glands, and pancreas. In addition, men produce hormones in their testes and women produce them in their ovaries.
Hormones are powerful. It takes only a tiny amount to cause big changes in cells or even your whole body. That is why too much or too little of a certain hormone can be serious. Laboratory tests can measure the hormone levels in your blood, urine, or saliva. Your health care provider may perform these tests if you have symptoms of a hormone disorder. Home pregnancy tests are similar - they test for pregnancy hormones in your urine.
[Learn More in MedlinePlus]
Poisoning
A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:
- Prescription or over-the-counter medicines taken in doses that are too high
- Overdoses of illegal drugs
- Carbon monoxide from gas appliances
- Household products, such as laundry powder or furniture polish
- Pesticides
- Indoor or outdoor plants
- Metals such as lead and mercury
The effects of poisoning range from short-term illness to brain damage, coma, and death. To prevent poisoning it is important to use and store products exactly as their labels say. Keep dangerous products where children can't get to them. Treatment for poisoning depends on the type of poison. If you suspect someone has been poisoned, call your local poison control center at 1-800-222-1222 right away.
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.