Version 2024
No Valid Principal Dx

2024 ICD-10-CM Diagnosis Code R65.1

Systemic inflammatory response syndrome (SIRS) of non-infectious origin

ICD-10-CM Code:
R65.1
ICD-10 Code for:
SIRS of non-infectious origin
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
    (R00–R99)
    • General symptoms and signs
      (R50-R69)
      • Symptoms and signs specifically associated with systemic inflammation and infection
        (R65)

R65.1 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of systemic inflammatory response syndrome (sirs) of non-infectious origin. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Specific Coding Applicable to SIRS of non-infectious origin

Non-specific codes like R65.1 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for sirs of non-infectious origin:

  • Use R65.10 for Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction - BILLABLE CODE

  • Use R65.11 for Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction - BILLABLE CODE

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.