2024 ICD-10-CM Diagnosis Code Q04.8

Other specified congenital malformations of brain

ICD-10-CM Code:
ICD-10 Code for:
Other specified congenital malformations of brain
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Code Navigator:

Code Classification

  • Congenital malformations, deformations and chromosomal abnormalities
    • Congenital malformations of the nervous system
      • Other congenital malformations of brain

Q04.8 is a billable diagnosis code used to specify a medical diagnosis of other specified congenital malformations of brain. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • 3C syndrome
  • Abnormality of neurogenesis
  • Abnormality of neurogenesis
  • Aprosencephaly
  • Aprosencephaly cerebellar dysgenesis
  • Aprosencephaly/atelencephaly spectrum
  • Aprosencephaly/atelencephaly spectrum
  • Athabaskan brainstem dysgenesis syndrome
  • CEDNIK syndrome
  • Central bilateral macrogyria
  • Cerebellar hemangioblastomatosis
  • Cerebral ventriculomegaly
  • Cerebral ventriculomegaly
  • Cerebral ventriculomegaly, cystic kidney disease
  • Cerebro-facio-thoracic dysplasia
  • Chiari malformation
  • Chiari malformation type IV
  • Coffin-Siris syndrome
  • Colpocephaly
  • Communicating hydrocephalus co-occurrent and due to congenital agenesis of arachnoid villi
  • Congenital abnormal shape of cerebellum
  • Congenital abnormal shape of cerebrum
  • Congenital aniridia
  • Congenital cerebral ventriculomegaly
  • Congenital cerebral ventriculomegaly
  • Congenital intrauterine infection-like syndrome
  • Congenital malformation of the meninges
  • Congenital pseudobulbar palsy
  • Congenital sequelae of disorders
  • Cortical dysplasia
  • Cortical dysplasia with hemimegalencephaly
  • Cystic malformation of posterior fossa
  • Dandy-Walker syndrome
  • Defect of telencephalic division
  • Dentate dysplasia
  • Diencephalic mesencephalic junction dysplasia
  • Ecchordosis physaliphora
  • Ectopic glial tissue
  • Ectopic gray matter
  • Ectopic gray matter in centrum ovale
  • Exencephaly
  • Focal cortical dysplasia type I
  • Focal cortical dysplasia type Ia
  • Focal cortical dysplasia type Ib
  • Focal cortical dysplasia type II
  • Focal cortical dysplasia type IIa
  • Focal cortical dysplasia type IIb
  • Gillespie syndrome
  • Hamartoma of brain
  • Hamartoma of hypothalamus
  • Hypothalamic hamartoma with gelastic seizure
  • Isolated focal cortical dysplasia
  • Laminar heterotopia
  • Localized cortical dysplasia
  • Macrogyria
  • Microdysgenesis
  • Nasal glial heterotopia
  • Neuronal heterotopia
  • Neuronal heterotopia
  • Neuronal heterotopia
  • Neuronal heterotopia
  • Neuronal heterotopia
  • Nodular heterotopia
  • Olivary heterotopia
  • Olive dysplasia
  • Periventricular nodular heterotopia
  • Pettigrew syndrome
  • Posterior fossa brain malformation, haemaniogma, arterial anomaly, cardiac defect and aortic coarctation, eye abnormality synodrome and sternal anomaly syndrome
  • Posterior fossa brain malformation, hemangioma, arterial anomaly, cardiac defect and aortic coarctation, and eye abnormality syndrome
  • PPM-X syndrome
  • Pseudobulbar palsy
  • Subcortical nodular heterotopia
  • Subependymal nodular heterotopia
  • Tubulinopathy-associated dysgyria
  • Ulegyria
  • Upper motor neuron disease
  • Ventriculomegaly due to developmental anomaly

Clinical Classification

Clinical Information

  • Pseudobulbar Palsy

    a syndrome characterized by dysarthria, dysphagia, dysphonia, impairment of voluntary movements of tongue and facial muscles, and emotional lability. this condition is caused by diseases that affect the motor fibers that travel from the cerebral cortex to the lower brain stem (i.e., corticobulbar tracts); including multiple sclerosis; motor neuron disease; and cerebrovascular disorders. (from adams et al., principles of neurology, 6th ed, p489)
  • Periventricular Nodular Heterotopia

    a disorder resulting from a defect in the pattern of neuronal migration in which ectopic collections of neurons lie along the lateral ventricles of the brain or just beneath, contiguously or in isolated patches.
  • ACD Gene Mutation|ACD, Shelterin Complex Subunit and Telomerase Recruitment Factor Gene Mutation|Adrenocortical Dysplasia Homolog (Mouse) Gene Mutation|PIP1 Gene Mutation|PTOP Gene Mutation|TINT1 Gene Mutation|TPP1 Gene Mutation

    a change in the nucleotide sequence of the acd gene.
  • ACD wt Allele|ACD, Mouse, Homolog of Gene|ACD, Shelterin Complex Subunit and Telomerase Recruitment Factor wt Allele|Adrenocortical Dysplasia Homolog (Mouse) Gene|PIP1|PTOP|TPP1

    human acd wild-type allele is located in the vicinity of 16q22.1 and is approximately 3 kb in length. this allele, which encodes adrenocortical dysplasia protein homolog, is involved in telomere protection.
  • Adrenocortical Dysplasia Protein Homolog|ACD|POT1 and TIN2 Organizing Protein|POT1 and TIN2-Interacting Protein|POT1- and TIN2- Organizing Protein|POT1-Interacting Protein 1|TIN2 Interacting Protein 1|TIN2-Interacting Protein 1|Telomere Protein TPP1

    adrenocortical dysplasia protein homolog (544 aa, ~58 kda) is encoded by the human acd gene. this protein plays a role in both the elongation and maintenance of telomeres.
  • Complex Cortical Dysplasia with other Brain Malformations 5|CDCBM5|TUBB2A Tubulinopathy

    an autosomal dominant condition caused by mutation(s) in the tubb2a gene, encoding tubulin beta-2a chain. it is characterized by cortical dysplasia and is associated with impaired intellectual development, hypotonia, global developmental delay, cortical dysplasia, and dysmorphic corpus callosum.
  • Cortical Dysplasia

    malformation of the cerebral cortex due to improper migration of neurons in utero.
  • Cortical Dysplasia-Focal Epilepsy Syndrome|CDFE Syndrome

    an autosomal recessive condition caused by mutation(s) in the cntnap2 gene, encoding contactin-associated protein-like 2. it is characterized by normal development until the onset of intractable focal seizures at age 1-9. after the onset of seizures, language regression, intellectual disability, hyperactivity, and impulsive behaviors begin to occur. the majority of children eventually fulfill the criteria for autism spectrum disorder.
  • Aprosencephaly

    a very rare congenital brain defect in which the cerebral cortex, striatum, globus pallidus, thalamus, hypothalamus, and eyes are absent or rudimentary.
  • Ecchordosis Physaliphora

    a very rare, slow growing, usually asymptomatic hamartomatous lesion that arises from ectopic notochordal tissue. morphologically it is characterized by the presence of typical physaliphorous cells in a myxoid background.
  • Pseudobulbar Palsy

    a condition affecting cranial nerves ix-xii resulting from upper motor neuron damage arising from a variety of causes.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Arnold-Chiari syndrome, type IV
  • Macrogyria

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Present on Admission (POA)

Q04.8 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA IndicatorReason for CodeCMS will pay the CC/MCC DRG?
YDiagnosis was present at time of inpatient admission.YES
NDiagnosis was not present at time of inpatient admission.NO
UDocumentation insufficient to determine if the condition was present at the time of inpatient admission.NO
WClinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.YES
1Unreported/Not used - Exempt from POA reporting. NO

Convert Q04.8 to ICD-9-CM

  • ICD-9-CM Code: 742.4 - Brain anomaly NEC
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education

Brain Malformations

Most brain malformations begin long before a baby is born. Something damages the developing nervous system or causes it to develop abnormally. Sometimes it's a genetic problem. In other cases, exposure to certain medicines, infections, or radiation during pregnancy interferes with brain development. Parts of the brain may be missing, abnormally small or large, or not fully developed.

Treatment depends upon the problem. In many cases, treatment only helps with symptoms. It may include antiseizure medicines, shunts to drain fluid from the brain, and physical therapy.

There are head malformations that do not involve the brain. Craniofacial disorders are the result of abnormal growth of soft tissue and bones in the face and head. It's common for new babies to have slightly uneven heads, but parents should watch the shape of their baby's head for possible problems.

NIH: National Institute of Neurological Disorders and Stroke

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.


[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.