Dermatopolymyositis (M33)
Clinical Information
Dermatomyositis - A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)
Polymyositis - Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9)
Diseases of the musculoskeletal system and connective tissue (M00–M99)
Systemic connective tissue disorders (M30-M36)
M33 Dermatopolymyositis
M33.0 Juvenile dermatomyositis
- M33.00 Juvenile dermatomyositis, organ involvement unspecified
- M33.01 Juvenile dermatomyositis with respiratory involvement
- M33.02 Juvenile dermatomyositis with myopathy
- M33.03 Juvenile dermatomyositis without myopathy
- M33.09 Juvenile dermatomyositis with other organ involvement
M33.1 Other dermatomyositis
- M33.10 Other dermatomyositis, organ involvement unspecified
- M33.11 Other dermatomyositis with respiratory involvement
- M33.12 Other dermatomyositis with myopathy
- M33.13 Other dermatomyositis without myopathy
- M33.19 Other dermatomyositis with other organ involvement
M33.2 Polymyositis
- M33.20 Polymyositis, organ involvement unspecified
- M33.21 Polymyositis with respiratory involvement
- M33.22 Polymyositis with myopathy
- M33.29 Polymyositis with other organ involvement
M33.9 Dermatopolymyositis, unspecified
- M33.90 Dermatopolymyositis, unspecified, organ involvement unspecified
- M33.91 Dermatopolymyositis, unspecified with respiratory involvement
- M33.92 Dermatopolymyositis, unspecified with myopathy
- M33.93 Dermatopolymyositis, unspecified without myopathy
- M33.99 Dermatopolymyositis, unspecified with other organ involvement
Dermatopolymyositis (M33)