2024 ICD-10-CM Diagnosis Code F48.1

Depersonalization-derealization syndrome

ICD-10-CM Code:
ICD-10 Code for:
Depersonalization-derealization syndrome
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Code Navigator:

Code Classification

  • Mental and behavioural disorders
    • Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders
      • Other nonpsychotic mental disorders

F48.1 is a billable diagnosis code used to specify a medical diagnosis of depersonalization-derealization syndrome. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Depersonalization
  • Depersonalization disorder
  • Depersonalization-derealization syndrome
  • Derealization
  • Derealization syndrome
  • Disturbance of perception associated with conversion and dissociative phenomenon
  • Disturbance of perception associated with conversion and dissociative phenomenon
  • Disturbance of perception associated with conversion and dissociative phenomenon
  • Feels own body is unreal

Clinical Classification

Clinical Information

  • Depersonalization

    state in which an individual perceives or experiences a sensation of unreality concerning the self or the environment; it is seen in disorders such as schizophrenia, affection disorders, organic mental disorders, and personality disorders. (apa, thesaurus of psychological index terms, 8th ed.)
  • CAPS DSM-5 With DSM IV Scoring 2016 Version - Derealization|CAP01-Derealization|CAP01-Derealization|CAP0130

    clinician-administered ptsd scale (current) dsm-5 with dsm iv scoring 2016 version (caps dsm-5 with dsm iv scoring 2016 version) dsm-5 scoring: derealization: persistent or recurrent experiences of unreality of surroundings (e.g., the world around the individual is experienced as unreal, dreamlike, distant, or distorted).
  • Derealization

    a feeling of altered reality characterized by a feeling of unreality, or being unreal.
  • HAMD 24 - Depersonalization and Derealisation|HAMD3-Depersonalization/Derealization|HAMD3-Depersonalization/Derealization|HAMD319

    hamilton depression rating scale-24 item (hamd 24) depersonalization and derealisation.
  • HAMD-21 - Depersonalization and Derealization|HAMD2-Depersonalization/Derealization|HAMD2-Depersonalization/Derealization|HAMD219

    hamilton depression rating scale 21 item (hamd-21) depersonalization and derealization; such as feelings of unreality, nihilistic ideas.
  • Depersonalization Disorder

    a disorder characterized by persistent or recurrent episodes of feeling detached from one's self (either one's body or one's mental processes), although the sufferer remains aware that this is only a feeling and does not represent reality.

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert F48.1 to ICD-9-CM

  • ICD-9-CM Code: 300.6 - Depersonalization disord

Patient Education

Mental Disorders

What are mental disorders?

Mental disorders (or mental illnesses) are conditions that affect your thinking, feeling, mood, and behavior. They may be occasional or long-lasting (chronic). They can affect your ability to relate to others and function each day.

What are some types of mental disorders?

There are many different types of mental disorders. Some common ones include:

  • Anxiety disorders, including panic disorder, obsessive-compulsive disorder, and phobias
  • Depression, bipolar disorder, and other mood disorders
  • Eating disorders
  • Personality disorders
  • Post-traumatic stress disorder
  • Psychotic disorders, including schizophrenia

What causes mental disorders?

There is no single cause for mental illness. A number of factors can contribute to risk for mental illness, such as:

  • Your genes and family history
  • Your life experiences, such as stress or a history of abuse, especially if they happen in childhood
  • Biological factors such as chemical imbalances in the brain
  • A traumatic brain injury
  • A mother's exposure to viruses or toxic chemicals while pregnant
  • Use of alcohol or recreational drugs
  • Having a serious medical condition like cancer
  • Having few friends, and feeling lonely or isolated

Mental disorders are not caused by character flaws. They have nothing to do with being lazy or weak.

Who is at risk for mental disorders?

Mental disorders are common. More than half of all Americans will be diagnosed with a mental disorder at some time in their life.

How are mental disorders diagnosed?

The steps to getting a diagnosis include:

  • A medical history
  • A physical exam and possibly lab tests, if your provider thinks that other medical conditions could be causing your symptoms
  • A psychological evaluation. You will answer questions about your thinking, feelings, and behaviors.

What are the treatments for mental disorders?

Treatment depends on which mental disorder you have and how serious it is. You and your provider will work on a treatment plan just for you. It usually involves some type of therapy. You may also take medicines. Some people also need social support and education on managing their condition.

In some cases, you may need more intensive treatment. You may need to go to a psychiatric hospital. This could be because your mental illness is severe. Or it could be because you are at risk of hurting yourself or someone else. In the hospital, you will get counseling, group discussions, and activities with mental health professionals and other patients.

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.


[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.