ICD-9 Diagnosis Code 281.4

Protein defic anemia

Diagnosis Code 281.4

ICD-9: 281.4
Short Description: Protein defic anemia
Long Description: Protein-deficiency anemia
This is the 2014 version of the ICD-9-CM diagnosis code 281.4

Code Classification
  • Diseases of the blood and blood-forming organs
    • Diseases of the blood and blood-forming organs (280-289)
      • 281 Other deficiency anemias

Information for Medical Professionals

Convert to ICD-10 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.
  • D53.0 - Protein deficiency anemia

Index of Diseases and Injuries
References found for the code 281.4 in the Index of Diseases and Injuries:

    • Aciduria 791.9
      • orotic (congenital) (hereditary) (pyrimidine deficiency) 281.4
    • Amino acid
      • deficiency 270.9
        • anemia 281.4
    • Anemia 285.9
      • amino acid deficiency 281.4
      • deficiency 281.9
        • amino acid 281.4
        • protein 281.4
      • orotic aciduric (congenital) (hereditary) 281.4
      • protein-deficiency 281.4
    • Deficiency, deficient
      • protein 260
        • anemia 281.4
    • Dysproteinemia 273.8
      • transient with copper deficiency 281.4
    • Orotaciduria, oroticaciduria (congenital) (hereditary) (pyrimidine deficiency) 281.4

Information for Patients


Also called: Iron poor blood

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.

Conditions that may lead to anemia include

  • Heavy periods
  • Pregnancy
  • Ulcers
  • Colon polyps or colon cancer
  • Inherited disorders
  • A diet that does not have enough iron, folic acid or vitamin B12
  • Blood disorders such as sickle cell anemia and thalassemia, or cancer
  • Aplastic anemia, a condition that can be inherited or acquired
  • G6PD deficiency, a metabolic disorder

Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.

Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.

NIH: National Heart, Lung, and Blood Institute

  • Anemia
  • Anemia - B12 deficiency
  • Anemia caused by low iron -- infants and toddlers
  • Anemia of chronic disease
  • Anemia of Inflammation and Chronic Disease - NIH
  • Antiparietal cell antibody test
  • Congenital spherocytic anemia
  • Ferritin blood test
  • Folate-deficiency anemia
  • Hemoglobin electrophoresis
  • Hemolytic anemia
  • Hemolytic anemia caused by chemicals and toxins
  • Immune hemolytic anemia
  • Iron deficiency anemia
  • Managing Chemotherapy Side Effects: Anemia - NIH - Easy-to-Read (National Cancer Institute)
  • Pernicious anemia
  • Serum free hemoglobin test
  • Serum iron test
  • Total iron binding capacity
  • Vitamin B12 level

[Read More]


Food provides the energy and nutrients you need to be healthy. If you don't get enough nutrients -- including proteins, carbohydrates, fats, vitamins, and minerals - you may suffer from malnutrition.

Causes of malnutrition include:

  • Lack of specific nutrients in your diet. Even the lack of one vitamin can lead to malnutrition.
  • An unbalanced diet
  • Certain medical problems, such as malabsorption syndromes and cancers

Symptoms may include fatigue, dizziness, and weight loss. Or, you may have no symptoms. To diagnose the cause of the problem, your doctor may do blood tests and a nutritional assessment. Treatment may include replacing the missing nutrients and treating the underlying cause.

  • Beriberi
  • Kwashiorkor
  • Malnutrition
  • Pellagra
  • Pica
  • Scurvy

[Read More]
Previous Code
Previous Code 281.3
Next Code
281.8 Next Code