ICD-9 Code 279.8

Other specified disorders involving the immune mechanism

Not Valid for Submission

279.8 is a legacy non-billable code used to specify a medical diagnosis of other specified disorders involving the immune mechanism. This code was replaced on September 30, 2015 by its ICD-10 equivalent.

ICD-9: 279.8
Short Description:Immune mechanism dis NEC
Long Description:Other specified disorders involving the immune mechanism

Convert 279.8 to ICD-10

The following crosswalk between ICD-9 to ICD-10 is based based on the General Equivalence Mappings (GEMS) information:

  • D84.1 - Defects in the complement system
  • D89.89 - Oth disrd involving the immune mechanism, NEC
  • M35.9 - Systemic involvement of connective tissue, unspecified

Code Classification

  • Endocrine, nutritional and metabolic diseases, and immunity disorders (240–279)
    • Other metabolic disorders and immunity disorders (270-279)
      • 279 Disorders involving the immune mechanism

Information for Medical Professionals

Synonyms

  • Abnormal host defense
  • Adult linear immunoglobulin A disease
  • Age-related immunodeficiency
  • Alternative pathway deficiency
  • Anaphylotoxin inactivator deficiency
  • Angioedema due to disorder of C1 esterase inhibitor
  • Autoimmune AND/OR graft reaction
  • Autologous state
  • Classical complement pathway abnormality
  • Clonal anergy
  • Complement 1q beta chain deficiency
  • Complement 1q deficiency
  • Complement 1q dysfunction
  • Complement 1r deficiency
  • Complement 1s deficiency
  • Complement 2 deficiency
  • Complement 3 deficiency
  • Complement 4 binding protein deficiency
  • Complement 4 deficiency
  • Complement 4A deficiency
  • Complement 4B deficiency
  • Complement 5 deficiency
  • Complement 5 dysfunction
  • Complement 5a inhibitor deficiency
  • Complement 6 deficiency
  • Complement 7 deficiency
  • Complement 8 alpha-gamma deficiency
  • Complement 8 beta chain deficiency
  • Complement 8 beta chain dysfunction
  • Complement 9 deficiency
  • Complement abnormality
  • Complement component deficiency
  • Complement deficiency disease
  • Complement receptor 1 deficiency
  • Complement receptor 3 deficiency
  • Complement receptor deficiency
  • Complement regulatory factor defect
  • Cutis laxa with complement deficiency
  • Decay accelerating factor deficiency
  • Defective phagocytic cell chemotaxis
  • Disorder of complement
  • Disorder of kidney due to kappa light chain disease
  • Disorder of kidney due to lambda light chain disease
  • Factor B deficiency
  • Factor D deficiency
  • Factor H deficiency
  • Familial C3B inhibitor deficiency syndrome
  • Familial immunoglobulin hypercatabolism
  • Hereditary C1 esterase inhibitor deficiency - deficient factor
  • Hereditary C1 esterase inhibitor deficiency - dysfunctional factor
  • Homologous restriction factor deficiency
  • Hyperimmune state
  • Hyperimmunoglobulin D with periodic fever
  • Immune reconstitution syndrome
  • Immunodeficiency associated with chromosomal abnormality
  • Immunodeficiency with major anomalies
  • Immunoglobulin hypercatabolism
  • Kappa light chain disease
  • Neutrophil secondary granule deficiency
  • Panniculitis with complement deficiency
  • Phagocytic cell defect
  • Postinfectious autoimmune reaction
  • Predominant humoral immune deficiency
  • Primary immune deficiency disorder
  • Primary immunoglobulin catabolism abnormality
  • Properdin deficiency disease
  • Reticuloendothelial blockade
  • Secondary immune deficiency disorder
  • Terminal component deficiency
  • T-lymphocyte deficiency
  • X-linked hyperimmunoglobulin M syndrome

Index to Diseases and Injuries

References found for the code 279.8 in the Index of Diseases and Injuries:


Information for Patients


Immune System and Disorders

What is the immune system?

Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases.

When germs such as bacteria or viruses invade your body, they attack and multiply. This is called an infection. The infection causes the disease that makes you sick. Your immune system protects you from the disease by fighting off the germs.

What are the parts of the immune system?

The immune system has many different parts, including:

  • Your skin, which can help prevent germs from getting into the body
  • Mucous membranes, which are the moist, inner linings of some organs and body cavities. They make mucus and other substances which can trap and fight germs.
  • White blood cells, which fight germs
  • Organs and tissues of the lymph system, such as the thymus, spleen, tonsils, lymph nodes, lymph vessels, and bone marrow. They produce, store, and carry white blood cells.

How does the immune system work?

Your immune system defends your body against substances it sees as harmful or foreign. These substances are called antigens. They may be germs such as bacteria and viruses. They might be chemicals or toxins. They could also be cells that are damaged from things like cancer or sunburn.

When your immune system recognizes an antigen, it attacks it. This is called an immune response. Part of this response is to make antibodies. Antibodies are proteins that work to attack, weaken, and destroy antigens. Your body also makes other cells to fight the antigen.

Afterwards, your immune system remembers the antigen. If it sees the antigen again, it can recognize it. It will quickly send out the right antibodies, so in most cases, you don't get sick. This protection against a certain disease is called immunity.

What are the types of immunity?

There are three different types of immunity:

  • Innate immunity is the protection that you are born with. It is your body's first line of defense. It includes barriers such as the skin and mucous membranes. They keep harmful substances from entering the body. It also includes some cells and chemicals which can attack foreign substances.
  • Active immunity, also called adaptive immunity, develops when you are infected with or vaccinated against a foreign substance. Active immunity is usually long-lasting. For many diseases, it can last your entire life.
  • Passive immunity happens when you receive antibodies to a disease instead of making them through your own immune system. For example, newborn babies have antibodies from their mothers. People can also get passive immunity through blood products that contain antibodies. This kind of immunity gives you protection right away. But it only lasts a few weeks or months.

What can go wrong with the immune system?

Sometimes a person may have an immune response even though there is no real threat. This can lead to problems such as allergies, asthma, and autoimmune diseases. If you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake.

Other immune system problems happen when your immune system does not work correctly. These problems include immunodeficiency diseases. If you have an immunodeficiency disease, you get sick more often. Your infections may last longer and can be more serious and harder to treat. They are often genetic disorders.

There are other diseases that can affect your immune system. For example, HIV is a virus that harms your immune system by destroying your white blood cells. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). People with AIDS have badly damaged immune systems. They get an increasing number of severe illnesses.


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ICD-9 Footnotes

General Equivalence Map Definitions
The ICD-9 and ICD-10 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.

Index of Diseases and Injuries Definitions

  • And - The word "and" should be interpreted to mean either "and" or "or" when it appears in a title.
  • Code also note - A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.
  • Code first - Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
  • Type 1 Excludes Notes - A type 1 Excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • Type 2 Excludes Notes - A type 2 Excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
  • Includes Notes - This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
  • Inclusion terms - List of terms is included under some codes. These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • NEC "Not elsewhere classifiable" - This abbreviation in the Alphabetic Index represents "other specified". When a specific code is not available for a condition, the Alphabetic Index directs the coder to the "other specified” code in the Tabular List.
  • NOS "Not otherwise specified" - This abbreviation is the equivalent of unspecified.
  • See - The "see" instruction following a main term in the Alphabetic Index indicates that another term should be referenced. It is necessary to go to the main term referenced with the "see" note to locate the correct code.
  • See Also - A "see also" instruction following a main term in the Alphabetic Index instructs that there is another main term that may also be referenced that may provide additional Alphabetic Index entries that may be useful. It is not necessary to follow the "see also" note when the original main term provides the necessary code.
  • 7th Characters - Certain ICD-10-CM categories have applicable 7th characters. The applicable 7th character is required for all codes within the category, or as the notes in the Tabular List instruct. The 7th character must always be the 7th character in the data field. If a code that requires a 7th character is not 6 characters, a placeholder X must be used to fill in the empty characters.
  • With - The word "with" should be interpreted to mean "associated with" or "due to" when it appears in a code title, the Alphabetic Index, or an instructional note in the Tabular List. The word "with" in the Alphabetic Index is sequenced immediately following the main term, not in alphabetical order.