ICD-9 Code 008.45

Intestinal infection due to Clostridium difficile

Not Valid for Submission

008.45 is a legacy non-billable code used to specify a medical diagnosis of intestinal infection due to clostridium difficile. This code was replaced on September 30, 2015 by its ICD-10 equivalent.

ICD-9: 008.45
Short Description:Int inf clstrdium dfcile
Long Description:Intestinal infection due to Clostridium difficile

Convert 008.45 to ICD-10

The following crosswalk between ICD-9 to ICD-10 is based based on the General Equivalence Mappings (GEMS) information:

  • A04.7 - Enterocolitis due to Clostridium difficile

Code Classification

  • Infectious and parasitic diseases (001–139)
    • Intestinal infectious diseases (001-009)
      • 008 Intestinal infections due to other organisms

Information for Medical Professionals

Index to Diseases and Injuries

References found for the code 008.45 in the Index of Diseases and Injuries:


Information for Patients


C. diff Infections

What is C. diff?

C. diff is a bacterium that can cause diarrhea and more serious intestinal conditions such as colitis. You may see it called other names - Clostridioides difficile (the new name), Clostridium difficile (an older name), and C. difficile. It causes close to half a million illnesses each year.

What causes C. diff infections?

C. diff bacteria are commonly found in the environment, but people usually only get C. diff infections when they are taking antibiotics. That's because antibiotics not only wipe out bad germs, but they also kill the good germs that protect your body against infections. The effect of antibiotics can last as long as several months. If you come in contact with C. diff germs during this time, you can get sick. You are more likely to get a C. diff infection if you take antibiotics for more than a week.

C. diff spreads when people touch food, surfaces, or objects that are contaminated with feces (poop) from a person who has C. diff.

Who is more likely to develop C. diff infections?

You are at more likely to get a C. diff infection if you:

  • Are taking antibiotics
  • Are 65 or older
  • Recently stayed in a hospital or nursing home
  • Have a weakened immune system
  • Have had a previous infection with C. diff or were exposed to it

What are the symptoms of C. diff infections?

The symptoms of C. diff infections include:

  • Diarrhea (loose, watery stools) or frequent bowel movements for several days
  • Fever
  • Stomach tenderness or pain
  • Loss of appetite
  • Nausea

Severe diarrhea causes you to lose a lot of fluids. This can put you at risk for dehydration.

How are C. diff infections diagnosed?

If you have been taking antibiotics recently and have symptoms of a C. diff infection, you should see your health care provider. Your provider will ask about your symptoms and do a lab test of your stool. In some cases, you might also need an imaging test to check for complications.

What are the treatments for C. diff infections?

Certain antibiotics can treat C. diff infections. If you were already taking a different antibiotic when you got C. diff, your provider may ask you to stop taking that one.

If you have a severe case, you may need to stay in the hospital. If you have very severe pain or serious complications, you may need surgery to remove the diseased part of your colon.

About 1 in 5 people who have had a C. diff infection will get it again. It could be that your original infection came back or that you have new infection. Contact your health care provider if your symptoms come back.

Can C. diff infections be prevented?

There are steps you can take to try to prevent getting or spreading C. diff:

  • Wash your hands with soap and water after you use the bathroom and before you eat.
  • If you have diarrhea, clean the bathroom that you used before anyone else uses it. Use bleach mixed with water or another disinfectant to clean the toilet seat, handle, and lid.

Health care providers can also help prevent C. diff infections by taking infection control precautions and improving how they prescribe antibiotics.

Centers for Disease Control and Prevention


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ICD-9 Footnotes

General Equivalence Map Definitions
The ICD-9 and ICD-10 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.

Index of Diseases and Injuries Definitions

  • And - The word "and" should be interpreted to mean either "and" or "or" when it appears in a title.
  • Code also note - A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.
  • Code first - Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
  • Type 1 Excludes Notes - A type 1 Excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • Type 2 Excludes Notes - A type 2 Excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
  • Includes Notes - This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
  • Inclusion terms - List of terms is included under some codes. These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • NEC "Not elsewhere classifiable" - This abbreviation in the Alphabetic Index represents "other specified". When a specific code is not available for a condition, the Alphabetic Index directs the coder to the "other specified” code in the Tabular List.
  • NOS "Not otherwise specified" - This abbreviation is the equivalent of unspecified.
  • See - The "see" instruction following a main term in the Alphabetic Index indicates that another term should be referenced. It is necessary to go to the main term referenced with the "see" note to locate the correct code.
  • See Also - A "see also" instruction following a main term in the Alphabetic Index instructs that there is another main term that may also be referenced that may provide additional Alphabetic Index entries that may be useful. It is not necessary to follow the "see also" note when the original main term provides the necessary code.
  • 7th Characters - Certain ICD-10-CM categories have applicable 7th characters. The applicable 7th character is required for all codes within the category, or as the notes in the Tabular List instruct. The 7th character must always be the 7th character in the data field. If a code that requires a 7th character is not 6 characters, a placeholder X must be used to fill in the empty characters.
  • With - The word "with" should be interpreted to mean "associated with" or "due to" when it appears in a code title, the Alphabetic Index, or an instructional note in the Tabular List. The word "with" in the Alphabetic Index is sequenced immediately following the main term, not in alphabetical order.