ICD-10 Diagnosis Code T88.3XXS

Malignant hyperthermia due to anesthesia, sequela

Diagnosis Code T88.3XXS

ICD-10: T88.3XXS
Short Description: Malignant hyperthermia due to anesthesia, sequela
Long Description: Malignant hyperthermia due to anesthesia, sequela
This is the 2017 version of the ICD-10-CM diagnosis code T88.3XXS

Code Classification
  • Injury, poisoning and certain other consequences of external causes
    • Complications of surgical and medical care, not elsewhere classified (T80-T88)
      • Oth complications of surgical and medical care, NEC (T88)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code T88.3XXS is grouped in the following Diagnostic Related Group(s) (MS-DRG v33.0)


Present on Admission (POA) Additional informationCallout TooltipPresent on Admission
The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement.

The code T88.3XXS is exempt from POA reporting.

Information for Patients


If you are having surgery, your doctor will give you medicine called an anesthetic. Anesthetics reduce or prevent pain. There are three main types:

  • Local - numbs one small area of the body. You stay awake and alert.
  • Regional - blocks pain in an area of the body, such an arm or leg. A common type is epidural anesthesia, which is often used during childbirth.
  • General - makes you unconscious. You do not feel any pain, and you do not remember the procedure afterwards.

You may also get a mild sedative to relax you. You stay awake but may not remember the procedure afterwards. Sedation can be used with or without anesthesia.

The type of anesthesia or sedation you get depends on many factors. They include the procedure you are having and your current health.

  • Conscious sedation for surgical procedures
  • Epidural block
  • General anesthesia
  • Spinal and epidural anesthesia

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Malignant hyperthermia Malignant hyperthermia is a severe reaction to particular drugs that are often used during surgery and other invasive procedures. Specifically, this reaction occurs in response to some anesthetic gases, which are used to block the sensation of pain, and with a muscle relaxant that is used to temporarily paralyze a person during a surgical procedure. If given these drugs, people at risk for malignant hyperthermia may experience muscle rigidity, breakdown of muscle fibers (rhabdomyolysis), a high fever, increased acid levels in the blood and other tissues (acidosis), and a rapid heart rate. Without prompt treatment, the complications of malignant hyperthermia can be life-threatening.People at increased risk for this disorder are said to have malignant hyperthermia susceptibility. Affected individuals may never know they have the condition unless they undergo testing or have a severe reaction to anesthesia during a surgical procedure. While this condition often occurs in people without other serious medical problems, certain inherited muscle diseases (including central core disease and multiminicore disease) are associated with malignant hyperthermia susceptibility.
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