ICD-10 Diagnosis Code T80.59XS

Anaphylactic reaction due to other serum, sequela

Diagnosis Code T80.59XS

ICD-10: T80.59XS
Short Description: Anaphylactic reaction due to other serum, sequela
Long Description: Anaphylactic reaction due to other serum, sequela
This is the 2017 version of the ICD-10-CM diagnosis code T80.59XS

Code Classification
  • Injury, poisoning and certain other consequences of external causes
    • Complications of surgical and medical care, not elsewhere classified (T80-T88)
      • Comp following infusion, transfusion and theraputc injection (T80)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code T80.59XS is grouped in the following Diagnostic Related Group(s) (MS-DRG v33.0)


Present on Admission (POA) Additional informationCallout TooltipPresent on Admission
The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement.

The code T80.59XS is exempt from POA reporting.

Information for Patients


Also called: Anaphylactic shock

Anaphylaxis is a serious allergic reaction. It can begin very quickly, and symptoms may be life-threatening. The most common causes are reactions to foods (especially peanuts), medications, and stinging insects. Other causes include exercise and exposure to latex. Sometimes no cause can be found.

It can affect many organs:

  • Skin - itching, hives, redness, swelling
  • Nose - sneezing, stuffy nose, runny nose
  • Mouth - itching, swelling of the lips or tongue
  • Throat - itching, tightness, trouble swallowing, swelling of the back of the throat
  • Chest - shortness of breath, coughing, wheezing, chest pain or tightness
  • Heart - weak pulse, passing out, shock
  • Gastrointestinal tract - vomiting, diarrhea, cramps
  • Nervous system - dizziness or fainting

If someone is having a serious allergic reaction, call 9-1-1. If an auto-injector is available, give the person the injection right away.

NIH: National Institute of Allergy and Infectious Diseases

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Blood Transfusion and Donation

Every year, millions of people in the United States receive life-saving blood transfusions. During a transfusion, you receive whole blood or parts of blood such as

  • Red blood cells - cells that carry oxygen to and from tissues and organs
  • Platelets - cells that form clots to control bleeding
  • Plasma - the liquid part of the blood that helps clotting. You may need it if you have been badly burned, have liver failure or a severe infection.

Most blood transfusions go very smoothly. Some infectious agents, such as HIV, can survive in blood and infect the person receiving the blood transfusion. To keep blood safe, blood banks carefully screen donated blood. The risk of catching a virus from a blood transfusion is low.

Sometimes it is possible to have a transfusion of your own blood. During surgery, you may need a blood transfusion because of blood loss. If you are having a surgery that you're able to schedule months in advance, your doctor may ask whether you would like to use your own blood, instead of donated blood. If so, you will need to have blood drawn one or more times before the surgery. A blood bank will store your blood for your use.

NIH: National Heart, Lung, and Blood Institute

  • Blood donation before surgery
  • Blood transfusions

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