2024 ICD-10-CM Diagnosis Code T50.7X5

Adverse effect of analeptics and opioid receptor antagonists

ICD-10-CM Code:
T50.7X5
ICD-10 Code for:
Adverse effect of analeptics and opioid receptor antagonists
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
        (T50)

T50.7X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of analeptics and opioid receptor antagonists. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of analeptics and opioid receptor antagonists

Non-specific codes like T50.7X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of analeptics and opioid receptor antagonists:

  • Use T50.7X5A for initial encounter - BILLABLE CODE

  • Use T50.7X5D for subsequent encounter - BILLABLE CODE

  • Use T50.7X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to ganglion blocking drug
  • Adverse reaction to levallorphan
  • Adverse reaction to lobeline
  • Adverse reaction to nalorphine
  • Doxapram adverse reaction
  • Ethamivan adverse reaction
  • Naloxone adverse reaction
  • Naltrexone adverse reaction
  • Nikethamide adverse reaction
  • Opioid antagonist adverse reaction
  • Pemoline adverse reaction
  • Respiratory stimulant adverse reaction

Clinical Information

  • Almitrine

    a respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. the drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. it may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.
  • Bemegride

    a cns stimulant that is used to induce convulsions in experimental animals. it has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.
  • Cyclazocine

    an analgesic with mixed narcotic agonist-antagonist properties.
  • Doxapram

    a central respiratory stimulant with a brief duration of action. (from martindale, the extra pharmocopoeia, 30th ed, p1225)
  • Levallorphan

    an opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties. it should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants. (from martindale, the extra pharmacopoeia, 30th ed, p683)
  • Lobeline

    an alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent. it has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
  • Nalorphine

    a narcotic antagonist with some agonist properties. it is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete.
  • Buprenorphine, Naloxone Drug Combination

    a pharmaceutical preparation that combines buprenorphine, an opioid analgesics with naloxone, a narcotic antagonists to reduce the potential for narcotic dependence in the treatment of pain. it may also be used for opioid substitution therapy.
  • Naloxone

    a specific opiate antagonist that has no agonist activity. it is a competitive antagonist at mu, delta, and kappa opioid receptors.
  • Naltrexone

    derivative of noroxymorphone that is the n-cyclopropylmethyl congener of naloxone. it is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. the fda has approved naltrexone for the treatment of alcohol dependence.
  • Nikethamide

    a central nervous system stimulant. it was formerly used in the treatment of barbiturate overdose but is now considered to be of no value for such purposes and may be dangerous. (from martindale, the extra pharmacopoeia, 30th ed, p1229)
  • Pemoline

    a central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
  • Pentylenetetrazole

    a pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. it is considered a non-competitive gamma-aminobutyric acid antagonist. pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
  • Picrotoxin

    a mixture of picrotoxinin and picrotin that is a noncompetitive antagonist at gaba-a receptors acting as a convulsant. picrotoxin blocks the gamma-aminobutyric acid-activated chloride ionophore. although it is most often used as a research tool, it has been used as a cns stimulant and an antidote in poisoning by cns depressants, especially the barbiturates.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AlmitrineT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
AmiphenazoleT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
Analeptic NECT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
BemegrideT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
BicucculineT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
CyclazocineT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
DimeflineT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
DimorpholamineT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
DoxapramT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
EtamivanT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
EthamivanT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
LeptazolT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
LevallorphanT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
LobelineT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
NalorphineT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
NaloxoneT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
NaltrexoneT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
NikethamideT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
PemolineT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
PentetrazoleT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
PentylenetetrazoleT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
PicrotoxinT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
PimecloneT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6
PrethcamideT50.7X1T50.7X2T50.7X3T50.7X4T50.7X5T50.7X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.