2024 ICD-10-CM Diagnosis Code T50.6X5D

Adverse effect of antidotes and chelating agents, subsequent encounter

ICD-10-CM Code:
T50.6X5D
ICD-10 Code for:
Adverse effect of antidotes and chelating agents, subs
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
        (T50)

T50.6X5D is a billable diagnosis code used to specify a medical diagnosis of adverse effect of antidotes and chelating agents, subsequent encounter. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

T50.6X5D is a subsequent encounter code, includes a 7th character and should be used after the patient has completed active treatment for a condition like adverse effect of antidotes and chelating agents. According to ICD-10-CM Guidelines a "subsequent encounter" occurs when the patient is receiving routine care for the condition during the healing or recovery phase of treatment. Subsequent diagnosis codes are appropriate during the recovery phase, no matter how many times the patient has seen the provider for this condition. If the provider needs to adjust the patient's care plan due to a setback or other complication, the encounter becomes active again.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acetylcholinesterase reactivator adverse reaction
  • Aldehyde dehydrogenase inhibitor adverse reaction
  • Antidote adverse reaction
  • Antidotes for pesticides adverse reaction
  • Benzodiazepine antagonist adverse reaction
  • Chelating agent adverse reaction
  • Chronic drug-induced renal disease
  • Dicobalt edetate adverse reaction
  • Digoxin specific antibody adverse reaction
  • Disodium edetate adverse reaction
  • Disulfiram adverse reaction
  • Drug-induced myasthenia
  • Drug-induced pseudoxanthoma elasticum
  • Edetate adverse reaction
  • Flumazenil adverse reaction
  • Hydrofluoric acid burn antidote adverse reaction
  • Ion exchange resin adverse reaction
  • Penicillamine adverse reaction
  • Penicillamine nephropathy
  • Penicillamine-induced myasthenia
  • Pralidoxime adverse reaction
  • Pseudoxanthoma elasticum
  • Pseudoxanthoma elasticum caused by penicillamine
  • Sodium nitrite adverse reaction
  • Sodium thiosulfate adverse reaction
  • Toxic neuromuscular junction disorder
  • Trisodium edetate adverse reaction

Clinical Classification

Clinical Information

  • Pseudoxanthoma Elasticum

    an inherited disorder of connective tissue with extensive degeneration and calcification of elastic tissue primarily in the skin, eye, and vasculature. at least two forms exist, autosomal recessive and autosomal dominant. this disorder is caused by mutations of one of the atp-binding cassette transporters. patients are predisposed to myocardial infarction and gastrointestinal hemorrhage.
  • ABCC6 wt Allele|ABC34|ARA|ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 wt Allele|ATP-Binding Cassette, Subfamily C, Member 6 Gene|EST349056|GACI2|MLP1|MOAT-E|MOATE|MRP6|PXE|PXE1|Pseudoxanthoma Elasticum Gene|URG7

    human abcc6 wild-type allele is located in the vicinity of 16p13.1 and is approximately 75 kb in length. this allele, which encodes multidrug resistance-associated protein 6, plays a role in the active transport of drugs across the plasma membrane. mutation of the gene is associated with pseudoxanthoma elasticum and generalized arterial calcification of infancy type 2.
  • Pseudoxanthoma Elasticum

    a rare, progressive, autosomal recessive inherited disorder caused by mutations in the abcc6 gene. it is characterized by calcification and fragmentation of the elastic fibers of the skin, retina, and cardiovascular system. signs and symptoms include skin plaques and bumps, thickened skin, retinal hemorrhage and obstruction of the blood vessels.
  • Spastic Paraplegia 56|Autosomal Recessive Spastic Paraplegia-56 with or without Pseudoxanthoma Elasticum|SPG56

    an autosomal recessive subtype of hereditary spastic paraplegia caused by mutation(s) in the cyp2u1 gene, encoding cytochrome p450 2u1.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)

T50.6X5D is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA IndicatorReason for CodeCMS will pay the CC/MCC DRG?
YDiagnosis was present at time of inpatient admission.YES
NDiagnosis was not present at time of inpatient admission.NO
UDocumentation insufficient to determine if the condition was present at the time of inpatient admission.NO
WClinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.YES
1Unreported/Not used - Exempt from POA reporting. NO

Convert T50.6X5D to ICD-9-CM

  • ICD-9-CM Code: V58.89 - Other specfied aftercare
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Table of Drugs and Chemicals

The parent code T50.6X5 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AntabuseT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Antidote NECT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Antidote NEC
  »heavy metal
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Chelating agent NECT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Cholinesterase reactivatorT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
CysteamineT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Deterrent, alcoholT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Detoxifying agentT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Disodium edetateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
DisulfiramT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
EDTAT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Ethylenediaminetetra-acetic acidT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Ethylenedinitrilotetra-acetateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Fytic acid, nonasodiumT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
GlutathioneT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
MethyleneT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylene
  »blue
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylene
  »chloride or dichloride (solvent) NEC
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylthionine chlorideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylthioninium chlorideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
NitrefazoleT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Obidoxime chlorideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
PAM (pralidoxime)T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
PenicillamineT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Pralidoxime (iodide)T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Pralidoxime (iodide)
  »chloride
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
ProtopamT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Tetraethylthiuram disulfideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Trisodium hydrogen edetateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
VersenateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.