2024 ICD-10-CM Diagnosis Code T50.6X5A

Adverse effect of antidotes and chelating agents, initial encounter

ICD-10-CM Code:
T50.6X5A
ICD-10 Code for:
Adverse effect of antidotes and chelating agents, init
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
        (T50)

T50.6X5A is a billable diagnosis code used to specify a medical diagnosis of adverse effect of antidotes and chelating agents, initial encounter. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

T50.6X5A is an initial encounter code, includes a 7th character and should be used while the patient is receiving active treatment for a condition like adverse effect of antidotes and chelating agents. According to ICD-10-CM Guidelines an "initial encounter" doesn't necessarily means "initial visit". The 7th character should be used when the patient is undergoing active treatment regardless if new or different providers saw the patient over the course of a treatment. The appropriate 7th character codes should also be used even if the patient delayed seeking treatment for a condition.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acetylcholinesterase reactivator adverse reaction
  • Aldehyde dehydrogenase inhibitor adverse reaction
  • Antidote adverse reaction
  • Antidotes for pesticides adverse reaction
  • Benzodiazepine antagonist adverse reaction
  • Chelating agent adverse reaction
  • Chronic drug-induced renal disease
  • Dicobalt edetate adverse reaction
  • Digoxin specific antibody adverse reaction
  • Disodium edetate adverse reaction
  • Disulfiram adverse reaction
  • Drug-induced myasthenia
  • Drug-induced pseudoxanthoma elasticum
  • Edetate adverse reaction
  • Flumazenil adverse reaction
  • Hydrofluoric acid burn antidote adverse reaction
  • Ion exchange resin adverse reaction
  • Penicillamine adverse reaction
  • Penicillamine nephropathy
  • Penicillamine-induced myasthenia
  • Pralidoxime adverse reaction
  • Pseudoxanthoma elasticum
  • Pseudoxanthoma elasticum caused by penicillamine
  • Sodium nitrite adverse reaction
  • Sodium thiosulfate adverse reaction
  • Toxic neuromuscular junction disorder
  • Trisodium edetate adverse reaction

Clinical Classification

Clinical Information

  • Pseudoxanthoma Elasticum

    an inherited disorder of connective tissue with extensive degeneration and calcification of elastic tissue primarily in the skin, eye, and vasculature. at least two forms exist, autosomal recessive and autosomal dominant. this disorder is caused by mutations of one of the atp-binding cassette transporters. patients are predisposed to myocardial infarction and gastrointestinal hemorrhage.
  • ABCC6 wt Allele|ABC34|ARA|ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 wt Allele|ATP-Binding Cassette, Subfamily C, Member 6 Gene|EST349056|GACI2|MLP1|MOAT-E|MOATE|MRP6|PXE|PXE1|Pseudoxanthoma Elasticum Gene|URG7

    human abcc6 wild-type allele is located in the vicinity of 16p13.1 and is approximately 75 kb in length. this allele, which encodes multidrug resistance-associated protein 6, plays a role in the active transport of drugs across the plasma membrane. mutation of the gene is associated with pseudoxanthoma elasticum and generalized arterial calcification of infancy type 2.
  • Pseudoxanthoma Elasticum

    a rare, progressive, autosomal recessive inherited disorder caused by mutations in the abcc6 gene. it is characterized by calcification and fragmentation of the elastic fibers of the skin, retina, and cardiovascular system. signs and symptoms include skin plaques and bumps, thickened skin, retinal hemorrhage and obstruction of the blood vessels.
  • Spastic Paraplegia 56|Autosomal Recessive Spastic Paraplegia-56 with or without Pseudoxanthoma Elasticum|SPG56

    an autosomal recessive subtype of hereditary spastic paraplegia caused by mutation(s) in the cyp2u1 gene, encoding cytochrome p450 2u1.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Convert T50.6X5A to ICD-9-CM

  • ICD-9-CM Code: 995.29 - Adv eff med/biol NEC/NOS
    Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.
  • ICD-9-CM Code: E947.2 - Adv eff antidotes NEC
    Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.

Table of Drugs and Chemicals

The parent code T50.6X5 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AntabuseT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Antidote NECT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Antidote NEC
  »heavy metal
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Chelating agent NECT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Cholinesterase reactivatorT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
CysteamineT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Deterrent, alcoholT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Detoxifying agentT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Disodium edetateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
DisulfiramT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
EDTAT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Ethylenediaminetetra-acetic acidT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Ethylenedinitrilotetra-acetateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Fytic acid, nonasodiumT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
GlutathioneT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
MethyleneT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylene
  »blue
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylene
  »chloride or dichloride (solvent) NEC
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylthionine chlorideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylthioninium chlorideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
NitrefazoleT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Obidoxime chlorideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
PAM (pralidoxime)T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
PenicillamineT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Pralidoxime (iodide)T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Pralidoxime (iodide)
  »chloride
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
ProtopamT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Tetraethylthiuram disulfideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Trisodium hydrogen edetateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
VersenateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.