2024 ICD-10-CM Diagnosis Code T50.6X5
Adverse effect of antidotes and chelating agents
- ICD-10-CM Code:
- T50.6X5
- ICD-10 Code for:
- Adverse effect of antidotes and chelating agents
- Is Billable?
- Not Valid for Submission
- Code Navigator:
T50.6X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of antidotes and chelating agents. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.
Specific Coding Applicable to Adverse effect of antidotes and chelating agents
Non-specific codes like T50.6X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of antidotes and chelating agents:
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Acetylcholinesterase reactivator adverse reaction
- Aldehyde dehydrogenase inhibitor adverse reaction
- Antidote adverse reaction
- Antidotes for pesticides adverse reaction
- Benzodiazepine antagonist adverse reaction
- Chelating agent adverse reaction
- Chronic drug-induced renal disease
- Dicobalt edetate adverse reaction
- Digoxin specific antibody adverse reaction
- Disodium edetate adverse reaction
- Disulfiram adverse reaction
- Drug-induced myasthenia
- Drug-induced pseudoxanthoma elasticum
- Edetate adverse reaction
- Flumazenil adverse reaction
- Hydrofluoric acid burn antidote adverse reaction
- Ion exchange resin adverse reaction
- Penicillamine adverse reaction
- Penicillamine nephropathy
- Penicillamine-induced myasthenia
- Pralidoxime adverse reaction
- Pseudoxanthoma elasticum
- Pseudoxanthoma elasticum caused by penicillamine
- Sodium nitrite adverse reaction
- Sodium thiosulfate adverse reaction
- Toxic neuromuscular junction disorder
- Trisodium edetate adverse reaction
Clinical Information
Cysteamine
a mercaptoethylamine compound that is endogenously derived from the coenzyme a degradative pathway. the fact that cysteamine is readily transported into lysosomes where it reacts with cystine to form cysteine-cysteamine disulfide and cysteine has led to its use in cystine depleting agents for the treatment of cystinosis.Disulfiram
a carbamate derivative used as an alcohol deterrent. it is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. when alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). it acts by inhibiting aldehyde dehydrogenase.Glutathione
a tripeptide with many roles in cells. it conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.Glutathione Disulfide
a glutathione dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.Glutathione Peroxidase
an enzyme catalyzing the oxidation of 2 moles of glutathione in the presence of hydrogen peroxide to yield oxidized glutathione and water.Glutathione Peroxidase GPX1
one of the most abundant isoenzymes of the glutathione peroxidase family. located in the cytosol and mitochondria, it catalyzes the reduction of hydrogen peroxide to water, functioning to limit the accumulation of hydrogen peroxide and modulating processes that utilize hydrogen peroxide; and also the reduction of other organic hydroperoxides to their corresponding alcohols.Glutathione Reductase
catalyzes the oxidation of glutathione to glutathione disulfide in the presence of nadp+. deficiency in the enzyme is associated with hemolytic anemia. formerly listed as ec 1.6.4.2.Glutathione S-Transferase pi
a glutathione transferase that catalyzes the conjugation of electrophilic substrates to glutathione. this enzyme has been shown to provide cellular protection against redox-mediated damage by free radicals.Glutathione Synthase
one of the enzymes active in the gamma-glutamyl cycle. it catalyzes the synthesis of glutathione from gamma-glutamylcysteine and glycine in the presence of atp with the formation of adp and orthophosphate. ec 6.3.2.3.Glutathione Transferase
a transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic free radicals as well as epoxides and arene oxides to glutathione. addition takes place at the sulfur. it also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite.Lactoylglutathione Lyase
an enzyme that catalyzes the interconversion of methylglyoxal and lactate, with glutathione serving as a coenzyme. ec 4.4.1.5.Phospholipid Hydroperoxide Glutathione Peroxidase
a selenoenzyme that converts glutathione plus fatty acid hydroperoxides to glutathione disulfide plus hydroxy fatty acids and water.Protein Disulfide Reductase (Glutathione)
an enzyme that catalyzes the reduction of a protein-disulfide in the presence of glutathione, forming a protein-dithiol. insulin is one of its substrates. ec 1.8.4.2.Obidoxime Chloride
cholinesterase reactivator occurring in two interchangeable isomeric forms, syn and anti.Penicillamine
3-mercapto-d-valine. the most characteristic degradation product of the penicillin antibiotics. it is used as an antirheumatic and as a chelating agent in wilson's disease.Pseudoxanthoma Elasticum
an inherited disorder of connective tissue with extensive degeneration and calcification of elastic tissue primarily in the skin, eye, and vasculature. at least two forms exist, autosomal recessive and autosomal dominant. this disorder is caused by mutations of one of the atp-binding cassette transporters. patients are predisposed to myocardial infarction and gastrointestinal hemorrhage.ABCC6 wt Allele|ABC34|ARA|ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 wt Allele|ATP-Binding Cassette, Subfamily C, Member 6 Gene|EST349056|GACI2|MLP1|MOAT-E|MOATE|MRP6|PXE|PXE1|Pseudoxanthoma Elasticum Gene|URG7
human abcc6 wild-type allele is located in the vicinity of 16p13.1 and is approximately 75 kb in length. this allele, which encodes multidrug resistance-associated protein 6, plays a role in the active transport of drugs across the plasma membrane. mutation of the gene is associated with pseudoxanthoma elasticum and generalized arterial calcification of infancy type 2.Pseudoxanthoma Elasticum
a rare, progressive, autosomal recessive inherited disorder caused by mutations in the abcc6 gene. it is characterized by calcification and fragmentation of the elastic fibers of the skin, retina, and cardiovascular system. signs and symptoms include skin plaques and bumps, thickened skin, retinal hemorrhage and obstruction of the blood vessels.Spastic Paraplegia 56|Autosomal Recessive Spastic Paraplegia-56 with or without Pseudoxanthoma Elasticum|SPG56
an autosomal recessive subtype of hereditary spastic paraplegia caused by mutation(s) in the cyp2u1 gene, encoding cytochrome p450 2u1.
Coding Guidelines
When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the aplicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Table of Drugs and Chemicals
The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.
According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.
Patient Education
Drug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
What is a drug interaction?
A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:
- Two drugs, such as aspirin and blood thinners
- Drugs and food, such as statins and grapefruit
- Drugs and supplements, such as gingko and blood thinners
- Drugs and medical conditions, such as aspirin and peptic ulcers
Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.
What are side effects?
Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.
What are drug allergies?
Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.
How can I stay safe when taking medicines?
When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.