2024 ICD-10-CM Diagnosis Code T50.0X6

Underdosing of mineralocorticoids and their antagonists

ICD-10-CM Code:
T50.0X6
ICD-10 Code for:
Underdosing of mineralocorticoids and their antagonists
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
        (T50)

T50.0X6 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of underdosing of mineralocorticoids and their antagonists. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Underdosing of mineralocorticoids and their antagonists

Non-specific codes like T50.0X6 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for underdosing of mineralocorticoids and their antagonists:

  • Use T50.0X6A for initial encounter - BILLABLE CODE

  • Use T50.0X6D for subsequent encounter - BILLABLE CODE

  • Use T50.0X6S for sequela - BILLABLE CODE

Clinical Information

  • Aldosterone

    a hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
  • Cytochrome P-450 CYP11B2

    a mitochondrial cytochrome p450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and nadph-specific flavoprotein. this enzyme, encoded by cyp11b2 gene, is important in the conversion of corticosterone to 18-hydroxycorticosterone and the subsequent conversion to aldosterone.
  • Mineralocorticoid Receptor Antagonists

    drugs that bind to and block the activation of mineralocorticoid receptors by mineralocorticoids such as aldosterone.
  • Receptors, Mineralocorticoid

    cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. the receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of dna.
  • Canrenoic Acid

    a synthetic pregnadiene derivative with anti-aldosterone activity.
  • Canrenone

    a synthetic pregnadiene compound with anti-aldosterone activity.
  • Fludrocortisone

    a synthetic mineralocorticoid with anti-inflammatory activity.
  • Spironolactone

    a potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. it is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (from martindale, the extra pharmacopoeia, 30th ed, p827)

Coding Guidelines

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AldactoneT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
AldosteroneT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
AntagonistT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »Aldosterone
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »alpha-adrenoreceptor
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »anticoagulant
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »beta-adrenoreceptor
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »extrapyramidal NEC
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »folic acid
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »H2 receptor
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »heavy metal
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »narcotic analgesic
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »opiate
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »pyrimidine
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Antagonist
  »serotonin
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Canrenoic acidT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
CanrenoneT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
DeoxycortoneT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
DesoxycorticosteroidT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
DesoxycortoneT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
FludrocortisoneT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Fludrocortisone
  »ENT agent
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Fludrocortisone
  »ophthalmic preparation
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Fludrocortisone
  »topical NEC
T50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
FluorhydrocortisoneT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
MineralocorticosteroidT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
Salt-retaining mineralocorticoidT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6
SpironolactoneT50.0X1T50.0X2T50.0X3T50.0X4T50.0X5T50.0X6

Patient Education


Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

  • Knowing your medicines. When you get a prescription, ask the name of the medicine and check to make sure that the pharmacy gave you the right medicine. Make sure that you understand how often you should take the medicine and how long you should take it.
  • Keeping a list of medicines.
    • Write down all of the medicines that you are taking, including the names of your medicines, how much you take, and when you take them. Make sure to include any over-the-counter medicines, vitamins, supplements, and herbs that you take.
    • List the medicines that you are allergic to or that have caused you problems in the past.
    • Take this list with you every time you see a health care provider.
  • Reading medicine labels and following the directions. Don't just rely on your memory - read the medication label every time. Be especially careful when giving medicines to children.
  • Asking questions. If you don't know the answers to these questions, ask your health care provider or pharmacist:
    • Why am I taking this medicine?
    • What are the common side effects?
    • What should I do if I have side effects?
    • When should I stop this medicine?
    • Can I take this medicine with the other medicines and supplements on my list?
    • Do I need to avoid certain foods or alcohol while taking this medicine?

Food and Drug Administration


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.