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  6. 2024 ICD-10-CM Code T49.4X5

2024 ICD-10-CM Diagnosis Code T49.4X5

Adverse effect of keratolytics, keratoplastics, and other hair treatment drugs and preparations

ICD-10-CM Code:
T49.4X5
ICD-10 Code for:
Adverse effect of keratolyt/keratplst/hair trmt drug
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs
        (T49)

T49.4X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of keratolytics, keratoplastics, and other hair treatment drugs and preparations. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of keratolyt/keratplst/hair trmt drug

Non-specific codes like T49.4X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of keratolyt/keratplst/hair trmt drug:

  • Use T49.4X5A for initial encounter - BILLABLE CODE

  • Use T49.4X5D for subsequent encounter - BILLABLE CODE

  • Use T49.4X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to dimethyl sulfoxide and/or idoxuridine
  • Adverse reaction to salicylate
  • Allergic reaction to hair dye
  • Contact dermatitis due to keratolytic
  • Dithranol adverse reaction
  • Dithranol burn
  • Dithranol cream adverse reaction
  • Dithranol ointment adverse reaction
  • Dithranol paste adverse reaction
  • Hypothyroidism caused by drug
  • Hypothyroidism caused by resorcinol
  • Podophyllum resin adverse reaction
  • Topical salicylic acid adverse reaction

Clinical Information

  • Allantoin

    a urea hydantoin that is found in urine and plants and is used in dermatological preparations.

  • Anthralin

    an anthracene derivative that disrupts mitochondria function and structure and is used for the treatment of dermatoses, especially psoriasis. it may cause folliculitis.

  • Capsaicin

    an alkylamide found in capsicum that acts at trpv cation channels.

  • Capsicum

    a plant genus of the family solanaceae. the hot peppers yield capsaicin, which activates vanilloid receptors. several varieties have sweet or pungent edible fruits that are used as vegetables when fresh and spices when the pods are dried.

  • Anacardic Acids

    a group of 6-alkyl salicylic acids that are found in anacardium and known for causing contact dermatitis.

  • Salicylates

    the salts or esters of salicylic acids, or salicylate esters of an organic acid. some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.

  • Salicylic Acid

    a compound obtained from the bark of the white willow and wintergreen leaves. it has bacteriostatic, fungicidal, and keratolytic actions.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs (T49). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)		 Poisoning
Accidental
(self-harm)		 Poisoning
Assault		 Poisoning
Undetermined		 Adverse
effect		 Underdosing
AllantoinT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Alum (medicinal)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Alum (medicinal)
  »nonmedicinal (ammonium) (potassium)
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
AnthralinT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
AntiseborrheicsT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Bleaching agent (medicinal)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
ButantroneT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Cade oilT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
CapsicumT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Carbazochrome (salicylate) (sodium sulfonate)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
ChlorothymolT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
ChloroxineT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
ChrysarobinT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
CollagenaseT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Corn curesT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
DepilatoryT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Desloughing agentT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Diachylon plasterT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Dimethylamine sulfateT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
DithranolT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
EuresolT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Flowers of sulfurT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Fumaric acidT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
HairT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Hair
  »dye
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Hair
  »preparation NEC
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
HemostypticT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
IchthyolT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Keratolytic drug NECT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Keratolytic drug NEC
  »anthracene
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Keratoplastic NECT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Lassar's pasteT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
MonobenzoneT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Podophyllum (resin)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Preparation, localT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Pyrithione zincT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
RubefacientT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Salicylic acidT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Salicylic acid
  »with benzoic acid
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Salicylic acid
  »congeners
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Salicylic acid
  »derivative
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Salicylic acid
  »salts
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Savin (oil)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
SelsunT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)
  »acid
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)
  »dioxide (gas)
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)
  »ether
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)
  »hydrogen
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)
  »medicinal (keratolytic) (ointment) NEC
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)
  »ointment
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)
  »pesticide (vapor)
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)
  »vapor NEC
T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
ThioglycolateT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
TioxoloneT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
TriacetoxyanthraceneT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
TrioxysalenT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Vleminckx's solutionT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
XenysalateT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.