2024 ICD-10-CM Diagnosis Code T47.3X5A

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Lactulose adverse reaction
• Mannitol adverse reaction
• Osmotic diuretic adverse reaction

Clinical Information

• Lactulose

  a synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. it has also been used in the diagnosis of gastrointestinal disorders. (from martindale, the extra pharmacopoeia, 30th ed, p887)

• Mannitol

  a diuretic and renal diagnostic aid related to sorbitol. it has little significant energy value as it is largely eliminated from the body before any metabolism can take place. it can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.

• Mannitol Dehydrogenases

  sugar alcohol dehydrogenases that have specificity for mannitol. enzymes in this category are generally classified according to their preference for a specific reducing cofactor.

• Mannitol Phosphates

  phosphoric acid esters of mannitol.

• Mannomustine

  nitrogen mustard derivative alkylating agent used as antineoplastic. it causes severe bone marrow depression and is a powerful vesicant.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system (T47). Use the following options for the aplicable episode of care:

• A - initial encounter
• D - subsequent encounter
• S - sequela

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

• Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Convert T47.3X5A to ICD-9-CM

• ICD-9-CM Code: 995.29 - Adv eff med/biol NEC/NOS
  Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.
• ICD-9-CM Code: E943.2 - Adv eff emoll cathartics
  Combination Flag - Multiple codes are needed to describe the source diagnosis code. Correct coding should be done based on contextual judgment.

Table of Drugs and Chemicals

The parent code T47.3X5 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Filter table of drugs and chemicals:

Substance	Poisoning Accidental (unintentional)	Poisoning Accidental (self-harm)	Poisoning Assault	Poisoning Undetermined	Adverse effect	Underdosing
Carbamide	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6
Carbamide   »peroxide	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6
Carbamide   »topical	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6
Epsom salt	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6
Lactulose	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6
Mannitol	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6
Mannitol   »hexanitrate	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6
Urea	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6
Urea   »peroxide	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6
Urea   »stibamine	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6
Urea   »topical	T47.3X1	T47.3X2	T47.3X3	T47.3X4	T47.3X5	T47.3X6

Patient Education

Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

• Two drugs, such as aspirin and blood thinners
• Drugs and food, such as statins and grapefruit
• Drugs and supplements, such as gingko and blood thinners
• Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.

[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.