2024 ICD-10-CM Diagnosis Code T45.0X6

Underdosing of antiallergic and antiemetic drugs

ICD-10-CM Code:
T45.0X6
ICD-10 Code for:
Underdosing of antiallergic and antiemetic drugs
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified
        (T45)

T45.0X6 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of underdosing of antiallergic and antiemetic drugs. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Underdosing of antiallergic and antiemetic drugs

Non-specific codes like T45.0X6 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for underdosing of antiallergic and antiemetic drugs:

  • Use T45.0X6A for initial encounter - BILLABLE CODE

  • Use T45.0X6D for subsequent encounter - BILLABLE CODE

  • Use T45.0X6S for sequela - BILLABLE CODE

Clinical Information

  • Astemizole

    antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
  • Brompheniramine

    histamine h1 antagonist used in treatment of allergies, rhinitis, and urticaria.
  • Cetirizine

    a potent second-generation histamine h1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
  • Chlorpheniramine

    a histamine h1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. it has also been used in veterinary applications. one of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
  • Cinnarizine

    a piperazine derivative having histamine h1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces parkinsonian disorders.
  • Clemastine

    a histamine h1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. it causes drowsiness.
  • Cyclizine

    a histamine h1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (from martindale, the extra pharmacopoeia, 30th ed, p935)
  • Cyproheptadine

    a serotonin antagonist and a histamine h1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
  • Dimenhydrinate

    a drug combination that contains diphenhydramine and theophylline. it is used for treating vertigo, motion sickness, and nausea associated with pregnancy.
  • Dimethindene

    a histamine h1 antagonist. it is used in hypersensitivity reactions, in rhinitis, for pruritus, and in some common cold remedies.
  • Diphenhydramine

    a histamine h1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. it has some undesired antimuscarinic and sedative effects.
  • Domperidone

    a specific blocker of dopamine receptors. it speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
  • Doxylamine

    histamine h1 antagonist with pronounced sedative properties. it is used in allergies and as an antitussive, antiemetic, and hypnotic. doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
  • Granisetron

    a serotonin receptor (5ht-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.
  • Ketotifen

    a cycloheptathiophene blocker of histamine h1 receptors and release of inflammatory mediators. it has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
  • Methapyrilene

    histamine h1 antagonist with sedative action used as a hypnotic and in allergies.
  • Metoclopramide

    a dopamine d2 antagonist that is used as an antiemetic.
  • Ondansetron

    a competitive serotonin type 3 receptor antagonist. it is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
  • Pheniramine

    one of the histamine h1 antagonists with little sedative action. it is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus.
  • Pyrilamine

    a histamine h1 antagonist. it has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. it is a common ingredient of cold remedies.
  • Terfenadine

    a selective histamine h1-receptor antagonist devoid of central nervous system depressant activity. the drug was used for allergy but withdrawn due to causing long qt syndrome.
  • Tripelennamine

    a histamine h1 antagonist with low sedative action but frequent gastrointestinal irritation. it is used to treat asthma; hay fever; urticaria; and rhinitis; and also in veterinary applications. tripelennamine is administered by various routes, including topically.
  • Triprolidine

    histamine h1 antagonist used in allergic rhinitis; asthma; and urticaria. it is a component of cough and cold medicines. it may cause drowsiness.

Coding Guidelines

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified (T45). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AcrivastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AlizaprideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antazolin (e)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antiallergic NECT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antiemetic drugT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AntihistamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antinausea drugT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AntistineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antivertigo drugT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AstemizoleT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AzatadineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AzelastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BamipineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BenadrylT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Benzhydramine (chloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BenzquinamideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Bisulepin (hydrochloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BonineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BromazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BromodiphenhydramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BrompheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BuclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CarbinoxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Cerium oxalateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Cerous oxalateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CetirizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CetoximeT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorcyclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChloropyramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChloropyrileneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorothenT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorphenamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorpheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorphenoxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Chlor-TrimetonT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CinnarizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ClemastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ClemizoleT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Clemizole
  »penicillin
T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ClorfenamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CyclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CyproheptadineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DeptropineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DexbrompheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DexchlorpheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DibenzheptropineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DifenidolT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimenhydrinateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimetaneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimethindeneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimetindeneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DiphenhydramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DiphenidolT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DiphenylpyralineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DomperidoneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DoxylamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DramamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
EmbramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
GranisetronT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
HomochlorcyclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
IsothipendylT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
KetotifenT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Levocabastine (hydrochloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
LoratidineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MarezineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MebhydrolinT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Meclizine (hydrochloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MeclozineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MephenhydramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MepyramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MethaphenileneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MethapyrileneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MetoclopramideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MoxastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
NytolT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
OndansetronT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
OxatomideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Percogesic [See Also: acetaminophen]T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PeriactinT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PhenindamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PhenyltoloxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PimethixeneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PipamazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PipoxizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PiprinhydrinateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PropiomazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyrathiazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyribenzamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyrilamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyrrobutamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
RotoxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
SetastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Sleep-ezeT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
SominexT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TerfenadineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ThenyldiamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Thonzylamine (systemic)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Thonzylamine (systemic)
  »mucosal decongestant
T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TiganT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TranilastT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TrimethobenzamideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TrimetonT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TripelennamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TriprolidineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TritoqualineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6

Patient Education


Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

  • Knowing your medicines. When you get a prescription, ask the name of the medicine and check to make sure that the pharmacy gave you the right medicine. Make sure that you understand how often you should take the medicine and how long you should take it.
  • Keeping a list of medicines.
    • Write down all of the medicines that you are taking, including the names of your medicines, how much you take, and when you take them. Make sure to include any over-the-counter medicines, vitamins, supplements, and herbs that you take.
    • List the medicines that you are allergic to or that have caused you problems in the past.
    • Take this list with you every time you see a health care provider.
  • Reading medicine labels and following the directions. Don't just rely on your memory - read the medication label every time. Be especially careful when giving medicines to children.
  • Asking questions. If you don't know the answers to these questions, ask your health care provider or pharmacist:
    • Why am I taking this medicine?
    • What are the common side effects?
    • What should I do if I have side effects?
    • When should I stop this medicine?
    • Can I take this medicine with the other medicines and supplements on my list?
    • Do I need to avoid certain foods or alcohol while taking this medicine?

Food and Drug Administration


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.