2024 ICD-10-CM Diagnosis Code T44.4X5
Adverse effect of predominantly alpha-adrenoreceptor agonists
- ICD-10-CM Code:
- T44.4X5
- ICD-10 Code for:
- Adverse effect of predominantly alpha-adrenocpt agonists
- Is Billable?
- Not Valid for Submission
- Code Navigator:
T44.4X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of predominantly alpha-adrenoreceptor agonists. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.
Specific Coding Applicable to Adverse effect of predominantly alpha-adrenocpt agonists
Non-specific codes like T44.4X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of predominantly alpha-adrenocpt agonists:
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Adverse reaction caused by decongestant
- Alpha-adrenoceptor agonist adverse reaction
- Amphetamine group adverse reaction
- Apraclonidine adverse reaction
- Central alpha-2 adrenergic receptor agonist adverse reaction
- Metaraminol adverse reaction
- Methoxamine adverse reaction
- Norepinephrine adverse reaction
- Oxedrine tartrate adverse reaction
- Phenylephrine adverse reaction
- Vasopressor adverse reaction
Clinical Information
Etilefrine
a phenylephrine-related beta-1 adrenergic and alpha adrenergic agonist used as a cardiotonic and antihypotensive agent.Metaraminol
a sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. it has been used primarily as a vasoconstrictor in the treatment of hypotension.Methoxamine
an alpha-1 adrenergic agonist that causes prolonged peripheral vasoconstriction.Norepinephrine
precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. norepinephrine is the principal transmitter of most postganglionic sympathetic fibers, and of the diffuse projection system in the brain that arises from the locus ceruleus. it is also found in plants and is used pharmacologically as a sympathomimetic.Norepinephrine Plasma Membrane Transport Proteins
sodium chloride-dependent neurotransmitter symporters located primarily on the plasma membrane of noradrenergic neurons. they remove norepinephrine from the extracellular space by high affinity reuptake into presynaptic terminals. the norepinephrine transporter regulates signal amplitude and duration at noradrenergic synapses and is the target of adrenergic uptake inhibitors.Phenylethanolamine N-Methyltransferase
a methyltransferase that catalyzes the reaction of s-adenosyl-l-methionine and phenylethanolamine to yield s-adenosyl-l-homocysteine and n-methylphenylethanolamine. it can act on various phenylethanolamines and converts norepinephrine into epinephrine. (from enzyme nomenclature, 1992) ec 2.1.1.28.Receptors, Adrenergic
cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. the two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. adrenergic receptors may also be classified according to the subtypes of g-proteins with which they bind; this scheme does not respect the alpha-beta distinction.Phenylephrine
an alpha-1 adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.
Coding Guidelines
When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (T44). Use the following options for the aplicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Table of Drugs and Chemicals
The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.
According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.
Patient Education
Drug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
What is a drug interaction?
A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:
- Two drugs, such as aspirin and blood thinners
- Drugs and food, such as statins and grapefruit
- Drugs and supplements, such as gingko and blood thinners
- Drugs and medical conditions, such as aspirin and peptic ulcers
Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.
What are side effects?
Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.
What are drug allergies?
Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.
How can I stay safe when taking medicines?
When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.