2024 ICD-10-CM Diagnosis Code T44.1X5
Adverse effect of other parasympathomimetics [cholinergics]
- ICD-10-CM Code:
- T44.1X5
- ICD-10 Code for:
- Adverse effect of other parasympathomimetics [cholinergics]
- Is Billable?
- Not Valid for Submission
- Code Navigator:
T44.1X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of other parasympathomimetics [cholinergics]. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.
Specific Coding Applicable to Adverse effect of other parasympathomimetics [cholinergics]
Non-specific codes like T44.1X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of other parasympathomimetics [cholinergics]:
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Adverse reaction to acetylcholine
- Bethanechol adverse reaction
- Carbachol adverse reaction
- Methacholine adverse reaction
- Non-allergic anaphylaxis caused by drug
- Non-allergic anaphylaxis caused by parasympathomimetic agent
- Parasympathomimetic adverse reaction
- Pilocarpine adverse reaction
Clinical Information
Acetylcholine
a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.Acetylcholine Release Inhibitors
compounds that block release of the neurotransmitter acetylcholine.Acetylcholinesterase
an enzyme that catalyzes the hydrolysis of acetylcholine to choline and acetate. in the cns, this enzyme plays a role in the function of peripheral neuromuscular junctions. ec 3.1.1.7.Cholinergic Agents
any drug used for its actions on cholinergic systems. included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. the term cholinergic agents is sometimes still used in the narrower sense of muscarinic agonists, although most modern texts discourage that usage.Cholinergic Agonists
drugs that bind to and activate cholinergic receptors.Cholinergic Antagonists
drugs that bind to but do not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.Cholinesterase Inhibitors
drugs that inhibit cholinesterases. the neurotransmitter acetylcholine is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. when cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.Receptors, Cholinergic
cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.Receptors, Muscarinic
one of the two major classes of cholinergic receptors. muscarinic receptors were originally defined by their preference for muscarine over nicotine. there are several subtypes (usually m1, m2, m3....) that are characterized by their cellular actions, pharmacology, and molecular biology.Receptors, Nicotinic
one of the two major classes of cholinergic receptors. nicotinic receptors were originally distinguished by their preference for nicotine over muscarine. they are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.Vesicular Acetylcholine Transport Proteins
vesicular amine transporter proteins that transport the neurotransmitter acetylcholine into small secretory vesicles. proteins of this family contain 12 transmembrane domains and exchange vesicular protons for cytoplasmic acetylcholine.Arecoline
an alkaloid obtained from the betel nut (areca catechu), fruit of a palm tree. it is an agonist at both muscarinic and nicotinic acetylcholine receptors. it is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. it has been used as a euphoriant in the pacific islands.Bethanechol
a slowly hydrolyzing muscarinic agonist with no nicotinic effects. bethanechol is generally used to increase smooth muscle tone, as in the gi tract following abdominal surgery or in urinary retention in the absence of obstruction. it may cause hypotension, heart rate changes, and bronchial spasm.Bethanechol Compounds
quaternary ammonium compounds that include bethanechol.Carbachol
a slowly hydrolyzed cholinergic agonist that acts at both muscarinic receptors and nicotinic receptors.Pilocarpine
a slowly hydrolyzed muscarinic agonist with no nicotinic effects. pilocarpine is used as a miotic and in the treatment of glaucoma.
Coding Guidelines
When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (T44). Use the following options for the aplicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Table of Drugs and Chemicals
The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.
According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.
Substance | Poisoning Accidental (unintentional) |
Poisoning Accidental (self-harm) |
Poisoning Assault |
Poisoning Undetermined |
Adverse effect |
Underdosing |
---|---|---|---|---|---|---|
Aceclidine | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Acetylcholine | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Acetylcholine »chloride | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Acetylcholine »derivative | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Arecoline | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Benzpyrinium bromide | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Bethanechol | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Bethanechol »chloride | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Carbachol | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Carbamylcholine chloride | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Cholinergic (drug) NEC | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Cholinergic (drug) NEC »muscle tone enhancer | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Cholinergic (drug) NEC »organophosphorus | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Cholinergic (drug) NEC »organophosphorus »insecticide | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Cholinergic (drug) NEC »organophosphorus »nerve gas | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Cholinergic (drug) NEC »trimethyl ammonium propanediol | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Methacholine | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Parasympathomimetic drug NEC | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Pilocarpine | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Pilocarpus (jaborandi) extract | T44.1X1 | T44.1X2 | T44.1X3 | T44.1X4 | T44.1X5 | T44.1X6 |
Patient Education
Drug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
What is a drug interaction?
A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:
- Two drugs, such as aspirin and blood thinners
- Drugs and food, such as statins and grapefruit
- Drugs and supplements, such as gingko and blood thinners
- Drugs and medical conditions, such as aspirin and peptic ulcers
Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.
What are side effects?
Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.
What are drug allergies?
Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.
How can I stay safe when taking medicines?
When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.