2024 ICD-10-CM Diagnosis Code T42.0X5

Adverse effect of hydantoin derivatives

ICD-10-CM Code:
T42.0X5
ICD-10 Code for:
Adverse effect of hydantoin derivatives
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs
        (T42)

T42.0X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of hydantoin derivatives. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of hydantoin derivatives

Non-specific codes like T42.0X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of hydantoin derivatives:

  • Use T42.0X5A for initial encounter - BILLABLE CODE

  • Use T42.0X5D for subsequent encounter - BILLABLE CODE

  • Use T42.0X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to hydantoin and/or hydantoin derivative
  • Class I antiarrhythmic adverse reaction
  • Drug-induced lupus erythematosus
  • Drug-induced lupus erythematosus due to diphenylhydantoin
  • Gingival disease due to drug
  • Gingival hypertrophy due to diphenylhydantoin
  • Hypertrophy of gingiva
  • Phenytoin adverse reaction
  • Purple glove syndrome

Clinical Information

  • Mephenytoin

    an anticonvulsant effective in tonic-clonic epilepsy (epilepsy, tonic-clonic). it may cause blood dyscrasias.
  • Phenytoin

    an anticonvulsant that is used to treat a wide variety of seizures. it is also an anti-arrhythmic and a muscle relaxant. the mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. the mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs (T42). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AlbutoinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
DilantinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
DiphenylhydantoinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
EpanutinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
EthotoinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
Hydantoin derivative NECT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
MephenytoinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
Mephenytoin
  »with phenobarbital
T42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
MetetoinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
MethetoinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
MethoinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
PhenantoinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
PhenytoinT42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6
Phenytoin
  »with Phenobarbital
T42.0X1T42.0X2T42.0X3T42.0X4T42.0X5T42.0X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.