2024 ICD-10-CM Diagnosis Code T41.295

Specific Coding Applicable to Adverse effect of other general anesthetics

Non-specific codes like T41.295 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of other general anesthetics:

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Adverse reaction to cyclopropane
• Adverse reaction to hallucinogen
• Inhalational anesthetics adverse reaction
• Ketamine adverse reaction
• Ketamine-induced biliary dilatation
• Propofol adverse reaction

Clinical Information

• Ketamine

  a cyclohexanone derivative used for induction of anesthesia. its mechanism of action is not well understood, but ketamine can block nmda receptors (receptors, n-methyl-d-aspartate) and may interact with sigma receptors.

• Propanidid

  an intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (from martindale, the extra pharmacopoeia, 30th ed, p918)

• Propofol

  an intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (from smith and reynard, textbook of pharmacology, 1992, 1st ed, p206). propofol has been used as anticonvulsants and antiemetics.

• Propofol Infusion Syndrome

  rare and often fatal drug complication which affects patients undergoing long-term treatment with high doses of propofol. it is characterized by metabolic acidosis; hyperlipidemia; rhabdomyolysis; cardiovascular circulatory collapse; cardiac failure; and kidney failure.

• Tiletamine

  proposed anesthetic with possible anticonvulsant and sedative properties.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases (T41). Use the following options for the aplicable episode of care:

• A - initial encounter
• D - subsequent encounter
• S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Filter table of drugs and chemicals:

Substance	Poisoning Accidental (unintentional)	Poisoning Accidental (self-harm)	Poisoning Assault	Poisoning Undetermined	Adverse effect	Underdosing
Cyclopropane	T41.291	T41.292	T41.293	T41.294	T41.295	T41.296
Disoprofol	T41.291	T41.292	T41.293	T41.294	T41.295	T41.296
Ketamine	T41.291	T41.292	T41.293	T41.294	T41.295	T41.296
Minaxolone	T41.291	T41.292	T41.293	T41.294	T41.295	T41.296
Oxybate sodium	T41.291	T41.292	T41.293	T41.294	T41.295	T41.296
Propanidid	T41.291	T41.292	T41.293	T41.294	T41.295	T41.296
Propofol	T41.291	T41.292	T41.293	T41.294	T41.295	T41.296
Tiletamine	T41.291	T41.292	T41.293	T41.294	T41.295	T41.296
Tribromoethanol, rectal	T41.291	T41.292	T41.293	T41.294	T41.295	T41.296

Patient Education

Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

• Two drugs, such as aspirin and blood thinners
• Drugs and food, such as statins and grapefruit
• Drugs and supplements, such as gingko and blood thinners
• Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.

[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.