2024 ICD-10-CM Diagnosis Code T39.8X5

Adverse effect of other nonopioid analgesics and antipyretics, not elsewhere classified

ICD-10-CM Code:
T39.8X5
ICD-10 Code for:
Adverse effect of nonopioid analges/antipyret, NEC
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics
        (T39)

T39.8X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of other nonopioid analgesics and antipyretics, not elsewhere classified. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of nonopioid analges/antipyret, NEC

Non-specific codes like T39.8X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of nonopioid analges/antipyret, nec:

  • Use T39.8X5A for initial encounter - BILLABLE CODE

  • Use T39.8X5D for subsequent encounter - BILLABLE CODE

  • Use T39.8X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to pyrabital
  • Ketorolac adverse reaction
  • Meptazinol adverse reaction
  • Nefopam adverse reaction
  • Pentosan polysulfate sodium maculopathy

Clinical Information

  • Clonixin

    anti-inflammatory analgesic.
  • Glafenine

    an anthranilic acid derivative with analgesic properties used for the relief of all types of pain.
  • Jamaica

    an island in the greater antilles in the west indies. its capital is kingston. it was discovered in 1494 by columbus and was a spanish colony 1509-1655 until captured by the english. its flourishing slave trade was abolished in the 19th century. it was a british colony 1655-1958 and a territory of the west indies federation 1958-62. it achieved full independence in 1962. the name is from the arawak xaymaca, rich in springs or land of springs. (from webster's new geographical dictionary, 1988, p564 & room, brewer's dictionary of names, 1992, p267)
  • Smilax

    a plant genus of the family smilacaceae. members contain smiglasides (phenylpropanoid glycosides) and steroidal saponins. commercially it is sometimes adulterated with hemidesmus, which would affect experimental results. drinks called sarsaparilla and root beer have been prepared from the smilaz ornata (jamaican sarsaparilla) and sassafras.
  • Ketorolac

    a pyrrolizine carboxylic acid derivative structurally related to indomethacin. it is an nsaid and is used principally for its analgesic activity. (from martindale the extra pharmacopoeia, 31st ed)
  • Ketorolac Tromethamine

    a pyrrolizine carboxylic acid derivative structurally related to indomethacin. it is a non-steroidal anti-inflammatory agent used for analgesia for postoperative pain and inhibits cyclooxygenase activity.
  • Meptazinol

    a narcotic antagonist with analgesic properties. it is used for the control of moderate to severe pain.
  • Nefopam

    non-narcotic analgesic chemically similar to orphenadrine. its mechanism of action is unclear. it is used for the relief of acute and chronic pain. (from martindale, the extra pharmacopoeia, 30th ed, p26)
  • Phenazopyridine

    a local anesthetic that has been used in urinary tract disorders. its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
  • Sumatriptan

    a serotonin agonist that acts selectively at 5ht1 receptors. it is used in the treatment of migraine disorders.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics (T39). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AcetylphenylhydrazineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
CarbipheneT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
ClonixinT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
CropropamideT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
Cropropamide
  »with crotethamide
T39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
CrotethamideT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
Crotethamide
  »with cropropamide
T39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
CryogenineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
CyclopyrabitalT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
DarvonT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
DiclonixineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
DoloxeneT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
EmorfazoneT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
EtomideT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
FloctafenineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
FluradolineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
GlafenineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
JamaicaT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
Jamaica
  »dogwood (bark)
T39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
Jamaica
  »ginger
T39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
Jamaica
  »ginger
    »root
T39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
KetorolacT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
LefetamineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
MeptazinolT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
MethopholineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
MetofolineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
NefopamT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
OxetoroneT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
Pentosan polysulfate (sodium)T39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
PerisoxalT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
PhenazopyridineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
PhenicarbazideT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
Phenyramidol, phenyramidonT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
Piscidia (bark) (erythrina)T39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
PyrabitalT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
PyridiumT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
Rimazolium metilsulfateT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
SumatriptanT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
TiaramideT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
TinoridineT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
VersidyneT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
ViminolT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6
ZactaneT39.8X1T39.8X2T39.8X3T39.8X4T39.8X5T39.8X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Pain Relievers

Pain relievers are medicines that reduce or relieve headaches, sore muscles, arthritis, or other aches and pains. There are many different pain medicines, and each one has advantages and risks. Some types of pain respond better to certain medicines than others. Each person may also have a slightly different response to a pain reliever.

Over-the-counter (OTC) medicines are good for many types of pain. There are two main types of OTC pain medicines: acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs). Aspirin, naproxen (Aleve), and ibuprofen (Advil, Motrin) are examples of OTC NSAIDs.

If OTC medicines don't relieve your pain, your doctor may prescribe something stronger. Many NSAIDs are also available at higher prescription doses. The most powerful pain relievers are opioids. They are very effective, but they can sometimes have serious side effects. There is also a risk of addiction. Because of the risks, you must use them only under a doctor's supervision.

There are many things you can do to help ease pain. Pain relievers are just one part of a pain treatment plan.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.