2024 ICD-10-CM Diagnosis Code R59.9

Enlarged lymph nodes, unspecified

ICD-10-CM Code:
R59.9
ICD-10 Code for:
Enlarged lymph nodes, unspecified
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
    (R00–R99)
    • General symptoms and signs
      (R50-R69)
      • Enlarged lymph nodes
        (R59)

R59.9 is a billable diagnosis code used to specify a medical diagnosis of enlarged lymph nodes, unspecified. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Unspecified diagnosis codes like R59.9 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Castleman disease
  • Finding of lymph node
  • Finding of lymph node
  • Finding of lymph node
  • Firm lymph node
  • Fluctuant lymph node
  • Hyperplastic lymph node
  • Lymphoid hyperplasia
  • Pulmonary venous hypertension due to compression of pulmonary great vein
  • Pulmonary venous hypertension due to compression of pulmonary great vein by lymphadenopathy
  • Shotty lymph node

Clinical Classification

Clinical Information

  • Castleman Disease

    large benign, hyperplastic lymph nodes. the more common hyaline vascular subtype is characterized by small hyaline vascular follicles and interfollicular capillary proliferations. plasma cells are often present and represent another subtype with the plasma cells containing igm and immunoglobulin a.
  • Atypical Gastric Lymphoid Hyperplasia|Atypical Gastric Lymphoid Hyperplasia of Stomach|Atypical Gastric Lymphoid Hyperplasia of the Stomach

    an atypical lymphoid hyperplasia involving the gastric mucosa.
  • Atypical Lymphoproliferative Disorder|Atypical Lymphoid Hyperplasia

    a lymphoproliferative disorder characterized by the presence of an atypical lymphocytic infiltrate.
  • Benign Lymphoid Hyperplasia

    a polyclonal proliferation of lymphocytes without evidence of cytologic atypia.
  • Castleman Disease, Hyaline-Vascular Type|Angiofollicular Lymphoid Hyperplasia, Hyaline-Vascular Type|Castleman's Disease, Hyaline-Vascular Type

    the commonest type of castleman disease. it is seen most commonly in the mediastinum. histologically this is characterized by hyalinized germinal centers surrounded by small lymphocytes in a concentric fashion, giving an onion skin appearance.
  • Castleman Disease, Plasma Cell Type|Angiofollicular Lymphoid Hyperplasia, Plasma Cell Type|Castleman's Disease, Plasma Cell Type

    castleman disease characterized by the presence of prominent hyalinized vessels in the germinal centers and prominent sheets of plasma cells in the interfollicular areas.
  • Castleman Disease|AFLH|Angiofollicular Lymphoid Hyperplasia|Castleman's Disease|Castleman's Tumor|Castleman's disease|GLNH|Giant Lymph Node Hyperplasia

    a disorder characterized by lymphoid hyperplasia in the lymph nodes. there are two histologic variants recognized: the hyaline-vascular type and the plasma cell type. in the hyaline vascular type there are hyalinized vessels present in the lymphoid follicles. in the plasma cell type there is pronounced plasma cell proliferation. clinically, the disease may be localized; manifested with localized lymphadenopathy, or multicentric; manifested with generalized lymphadenopathy, fever, organomegaly, and sometimes poems syndrome. in contrast to patients with localized disease who are usually cured following resection of the lesion, patients with the multicentric form of the disease may follow a progressive clinical course, complicated by infection, kaposi sarcoma or lymphoma.
  • Cervical Florid Reactive Lymphoid Hyperplasia

    a dense, superficial benign lymphoid cell proliferation in the cervix. it almost always occurs in premenopausal women. it is composed of a mixture of large and small lymphocytes including immunoblasts. plasma cells and neutrophils are also present. immunohistochemical studies reveal a mixture of b and t lymphocytes, and polytypic plasma cells.
  • Conjunctival Reactive Lymphoid Hyperplasia

    a polyclonal proliferation of lymphoid tissue in the conjunctiva that typically occurs in young adults. it usually presents as a unilateral, red or orange, painless swelling and is probably caused by chronic antigen stimulation. (who 2018)
  • Epithelioid Hemangioma|Angiolymphoid Hyperplasia with Eosinophilia|Epithelioid hemangioma|Histiocytoid Hemangioma|Histiocytoid hemangioma

    a hemangioma characterized by the presence of epithelioid endothelial cells.
  • Follicular Bronchitis/Bronchiolitis|Follicular Hyperplasia of BALT|Pulmonary Lymphoid Hyperplasia

    a non-neoplastic disorder characterized by the formation of reactive lymphoid follicles adjacent to distal bronchi and bronchioles. it presents with mild shortness of breath and is associated with immunodeficiency syndromes and collagen vascular disorders.
  • Immunodeficiency-Related Lymphoproliferative Disorder|Immunodeficiency-Associated Lymphoproliferative Disorder|Lymphoid Hyperplasia Arising in Setting of Immune Deficiency/Dysregulation

    a lymphoproliferative disorder that occurs in a patient with immunodeficiency.
  • Lacrimal Gland Reactive Lymphoid Hyperplasia

    a polyclonal proliferation of lymphoid tissue in the lacrimal gland. it usually presents as painless palpable masses leading to globe displacement, decreased motility, diplopia, and ptosis. it has a tendency to involve bilateral lacrimal glands. there is a higher incidence in females and in the setting of autoimmune disease. (who 2018)
  • Lymphoid Hyperplasia

    a benign or malignant, diffuse and/or follicular lymphocytic proliferation.
  • Multicentric Castleman Disease|Idiopathic Multicentric Castleman Disease|MCD|Multicentric Angiofollicular Lymphoid Hyperplasia|Multicentric Angiofollicular Lymphoid Hyperplasia|Multicentric Castleman's Disease|iMCD

    castleman disease characterized by fever, generalized lymphadenopathy, hypergammaglobulinemia, and dysfunction of multiple organs. other signs and symptoms include anemia, thrombocytopenia, hepatomegaly, peripheral neuropathy and pleural effusions. morphologically, in the majority of cases the lymph nodes show features of castleman disease of the plasma cell type. in a minority of cases, changes of castleman disease of the hyaline-vascular type are seen. in contrast to patients with localized disease who are usually cured following resection of the lesion, patients with the multicentric form of the disease may follow a progressive clinical course, complicated by infection, kaposi sarcoma, or lymphoma.
  • Nodular Lymphoid Hyperplasia of Lung

    a rare, reactive lesion in the lung parenchyma. it is characterized by the formation of a single or several nodules that are composed of lymphocytic infiltrates with reactive germinal centers.
  • Primary Choroidal Non-Hodgkin Lymphoma|Choroidal Reactive Lymphoid Hyperplasia|Primary Choroidal Lymphoma

    an indolent, low-grade b-cell non-hodgkin lymphoma that arises from the choroid. it is characterized by the presence of a diffuse infiltrate of small, round lymphocytes. lymphoid follicles with germinal centers may be present. in the past these tumors were termed 'reactive lymphoid hyperplasia'. now they are considered low-grade b-cell lymphomas, most commonly extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue.
  • Primary Uveal Non-Hodgkin Lymphoma|Primary Uveal Lymphoma|Uveal Reactive Lymphoid Hyperplasia

    an indolent, low-grade b-cell non-hodgkin lymphoma that arises from the choroid, iris, or ciliary body. it is characterized by the presence of a diffuse infiltrate of small, round lymphocytes. lymphoid follicles with germinal centers may be present. in the past these tumors were termed 'reactive lymphoid hyperplasia'. now they are considered low-grade b-cell lymphomas, most commonly extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue.
  • Skin Epithelioid Hemangioma|Angiolymphoid Cutaneous Hyperplasia|Angiolymphoid Hyperplasia of Skin|Angiolymphoid Hyperplasia of the Skin|Epithelioid Hemangioma of Skin|Epithelioid Hemangioma of the Skin|Histiocytoid Hemangioma of Skin|Histiocytoid Hemangioma of the Skin

    a hemangioma arising from the skin. it is characterized by the presence of epithelioid endothelial cells.
  • Unicentric Castleman Disease|Localized Angiofollicular Lymphoid Hyperplasia|Localized Angiofollicular Lymphoid Hyperplasia|Localized Castleman Disease|UCD

    castleman disease that presents with localized lymphadenopathy.

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert R59.9 to ICD-9-CM

  • ICD-9-CM Code: 785.6 - Enlargement lymph nodes
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.