ICD-10 Diagnosis Code R53

Malaise and fatigue

Diagnosis Code R53

ICD-10: R53
Short Description: Malaise and fatigue
Long Description: Malaise and fatigue
This is the 2017 version of the ICD-10-CM diagnosis code R53

Code Classification
  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
    • General symptoms and signs (R50-R69)
      • Malaise and fatigue (R53)

Information for Patients


Also called: Tiredness, Weariness

Everyone feels tired now and then. Sometimes you may just want to stay in bed. But, after a good night's sleep, most people feel refreshed and ready to face a new day. If you continue to feel tired for weeks, it's time to see your doctor. He or she may be able to help you find out what's causing your fatigue and recommend ways to relieve it.

Fatigue itself is not a disease. Medical problems, treatments, and personal habits can add to fatigue. These include

  • Taking certain medicines, such as antidepressants, antihistamines, and medicines for nausea and pain
  • Having medical treatments, like chemotherapy and radiation
  • Recovering from major surgery
  • Anxiety, stress, or depression
  • Staying up too late
  • Drinking too much alcohol or too many caffeinated drinks
  • Pregnancy

One disorder that causes extreme fatigue is chronic fatigue syndrome (CFS). This fatigue is not the kind of tired feeling that goes away after you rest. Instead, it lasts a long time and limits your ability to do ordinary daily activities.

NIH: National Institute on Aging

  • Coping with cancer -- managing fatigue
  • Fatigue

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