ICD-10 Diagnosis Code M35

Other systemic involvement of connective tissue

Diagnosis Code M35

ICD-10: M35
Short Description: Other systemic involvement of connective tissue
Long Description: Other systemic involvement of connective tissue
This is the 2018 version of the ICD-10-CM diagnosis code M35

Not Valid for Submission
The code M35 is a "header" and not valid for submission for HIPAA-covered transactions.

Code Classification
  • Diseases of the musculoskeletal system and connective tissue (M00–M99)
    • Systemic connective tissue disorders (M30-M36)
      • Other systemic involvement of connective tissue (M35)

Information for Patients


Connective Tissue Disorders

Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular glue" that gives your body parts their shape and helps keep them strong. It also helps some of your tissues do their work. It is made of many kinds of proteins. Cartilage and fat are types of connective tissue.

Over 200 disorders that impact connective tissue. There are different types:

  • Genetic disorders, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta
  • Autoimmune disorders, such as lupus and scleroderma
  • Cancers, like some types of soft tissue sarcoma

Each disorder has its own symptoms and needs different treatment.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

  • Dupuytrens contracture (Medical Encyclopedia)


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