2024 ICD-10-CM Diagnosis Code L12.2

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Bullous eruption of childhood
• Bullous pemphigoid
• Childhood bullous pemphigoid
• Chronic bullous dermatosis of childhood
• Chronic localized pemphigoid
• Conjunctivitis associated with autoimmune skin disorder
• Conjunctivitis associated with dermatitis herpetiformis
• Dermatitis herpetiformis
• Herpetiform eruption
• Hydroa herpetiformis
• Linear IgA dermatosis
• Localized pemphigoid
• Oral mucosal involvement by dermatitis herpetiformis
• Pemphigoid
• Pretibial pemphigoid

Clinical Information

• Dermatitis Herpetiformis

  rare, chronic, papulo-vesicular disease characterized by an intensely pruritic eruption consisting of various combinations of symmetrical, erythematous, papular, vesicular, or bullous lesions. the disease is strongly associated with the presence of hla-b8 and hla-dr3 antigens. a variety of different autoantibodies has been detected in small numbers in patients with dermatitis herpetiformis.

• Dermatitis Herpetiformis

  a chronic autoimmune skin disorder characterized by the development of pruritic papulovesicular and bullous lesions in the elbows, knees, buttocks, and back. it is associated with an increased expression of hla-a1, hla-b8, and hla-dr3 antibodies.

• Bullous Pemphigoid

  an autoimmune chronic skin disorder characterized by the presence of large blisters. it usually affects elderly people and tends to subside spontaneously.

• COL17A1 wt Allele|BA16H23.2|BA16H23.2 (Collagen, Type XVII, Alpha 1 (BP180)) Gene|BP180|BPA-2|BPAG2|Bullous Pemphigoid Antigen 2 (180kD) Gene|Collagen Type XVII Alpha 1 Chain wt Allele|Collagen, Type XVII, Alpha 1 Gene|Collagen, Type XVII, Alpha-1 Gene|ERED|LAD-1

  human col17a1 wild-type allele is located in the vicinity of 10q25.1 and is approximately 55 kb in length. this allele, which encodes collagen alpha-1(xvii) chain protein, is involved in hemidesmosome formation and keratinocyte adhesion. mutation of the gene and immunoreactivity during revertant mosaicism is associated with both generalized atrophic benign and junctional epidermolysis bullosa. mutations in the gene are also associated with epithelial recurrent erosion dystrophy.

• Collagen Alpha-1(XVII) Chain|180 kDa Bullous Pemphigoid Antigen 2|Alpha 1 Type XVII Collagen|Bullous Pemphigoid Antigen 2|COL17A1|Collagen Type XVII Alpha 1 Chain|Collagen Type XVII Alpha 1 Polypeptide|Type XVII Collagen Alpha-1

  collagen alpha-1(xvii) chain (1497 aa, ~150 kda) is encoded by the human col17a1 gene. this protein plays a role in the attachment of keratinocytes to the basement membrane.

• Dystonin|230 kDa Bullous Pemphigoid Antigen|230/240 kDa Bullous Pemphigoid Antigen|Bullous Pemphigoid Antigen|Bullous Pemphigoid Antigen 1|Bullous Pemphigoid Antigen 1, 230/240kDa|DST|Dystonia Musculorum Protein|Hemidesmosomal Plaque Protein|Trabeculin-Beta

  dystonin (7570 aa, ~860 kda) is encoded by the human dst gene. this protein plays a structural role in cytoskeleton networks.

• Benign Mucous Membrane Pemphigoid

  a chronic autoimmune disorder characterized by the development of blisters and ulcers in mucous membranes. it affects most often the gums, eyelids and genital mucosa sites.

• Ocular Cicatricial Pemphigoid

  a chronic autoimmune disorder that belongs to the mucous membrane pemphigoid disorders. it is characterized by bilateral scarring and opacification of the conjunctivae. it presents with pain and burning sensation in the eyes and photophobia. it leads to blindness.

• Pemphigoid

  a rare autoimmune blistering skin disorder that resembles pemphigus but is histologically and clinically distinguishable by lack of evidence of acantholysis and a generally benign course.

• Pemphigoid Antibody Measurement|PEMAB|Pemphigoid Antibodies|Pemphigoid Antibodies

  the determination of the amount of pemphigoid antibodies present in a sample.

• Pemphigoid Gestationis|Gestational Pemphigoid|Gestational Pemphigoid|Herpes Gestationis

  an autoimmune bullous dermatitis that develops during pregnancy, most often during the second and third trimesters.

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

• Pediatric diagnoses - The Medicare Code Editor detects inconsistencies in pediatric cases by checking a patient's age and any diagnosis on the patient's record. The pediatric code edits apply to patients age range is 0–17 years inclusive (e.g., Reye's syndrome, routine child health exam).

L12.2 is grouped with Diagnostic Related Groups - MS-DRG Mapping

Diagnostic Related Groups (DRGs) are a classification system used to group together diagnosis codes for the purpose of reimbursement and healthcare management. DRGs are used to standardize the way hospitals and other providers are paid for inpatient services. In this system patients are grouped together based on their principal diagnosis in areas referred to as Major Diagnostic Categories (MDC). Once a patient is assigned a particular diagnostic category, providers receive a predetermined payment rate for the services rendered. This reimbursement rate is often fixed and is meant to cover the cost of care for that patient. Reimbursement is also affected by the relative weight of a diagnostic related group based on the severity of a patient's illness and the associated cost of care during hospitalization.

Diagnostic related groups encourage healthcare providers to focus on quality and efficiency in patient care while managing costs effectively. The diagnosis code is present in the following groups for version MS-DRG V41.0 applicable from 10/01/2023 through 09/30/2024.

MS-DRG	MS-DRG Title	MCD	Relative Weight
606	MINOR SKIN DISORDERS WITH MCC	09	1.5858
607	MINOR SKIN DISORDERS WITHOUT MCC	09	0.8935

The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.

Convert L12.2 to ICD-9-CM

• ICD-9-CM Code: 694.2 - Juven dermat herpetiform

Patient Education

Pemphigus

Pemphigus is an autoimmune disorder. If you have it, your immune system attacks healthy cells in your skin and mouth, causing blisters and sores. No one knows the cause. Pemphigus does not spread from person to person. It does not appear to be inherited. But some people's genes put them more at risk for pemphigus.

Pemphigoid is also an autoimmune skin disease. It leads to deep blisters that do not break easily. Pemphigoid is most common in older adults and may be fatal for older, sick patients.

Doctors diagnose pemphigus with a physical exam, a biopsy, and blood tests. The treatment of pemphigus and pemphigoid is the same: one or more medicines to control symptoms. These may include:

• Steroids, which reduce inflammation
• Drugs that suppress the immune system response
• Antibiotics to treat associated infections

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.