Certain disorders involving the immune mechanism (D80-D89)

Browse all the diagnosis codes used for certain disorders involving the immune mechanism (d80-d89). For easy navigation, the diagnosis codes are sorted in alphabetical order and grouped by sections. Each section is clearly marked with its description, and the corresponding three-digit code range. This format makes it simple to browse diagnosis codes in this chapter or section and find what you're looking for. We've also added green checkmark icons to label billable codes, and red warning icons for non-billable ones. This makes it easy to identify which codes can be billed.

Instructional Notations

Includes

This note appears immediately under a three character code title to further define, or give examples of, the content of the category.

  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Type 1 Excludes

A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

  • autoimmune disease systemic NOS M35.9
  • functional disorders of polymorphonuclear neutrophils D71
  • human immunodeficiency virus [HIV] disease B20
  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)

    • Certain disorders involving the immune mechanism (D80-D89)

        • Immunodeficiency with predominantly antibody defects (D80)

        • D80 Immunodeficiency with predominantly antibody defects
        • D80.0 Hereditary hypogammaglobulinemia
        • D80.1 Nonfamilial hypogammaglobulinemia
        • D80.2 Selective deficiency of immunoglobulin A [IgA]
        • D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
        • D80.4 Selective deficiency of immunoglobulin M [IgM]
        • D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
        • D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
        • D80.7 Transient hypogammaglobulinemia of infancy
        • D80.8 Other immunodeficiencies with predominantly antibody defects
        • D80.9 Immunodeficiency with predominantly antibody defects, unspecified
        • Combined immunodeficiencies (D81)

        • D81 Combined immunodeficiencies
        • D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
        • D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
        • D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
        • D81.3 Adenosine deaminase [ADA] deficiency
        • D81.30 Adenosine deaminase deficiency, unspecified
        • D81.31 Severe combined immunodeficiency due to adenosine deaminase deficiency
        • D81.32 Adenosine deaminase 2 deficiency
        • D81.39 Other adenosine deaminase deficiency
        • D81.4 Nezelof's syndrome
        • D81.5 Purine nucleoside phosphorylase [PNP] deficiency
        • D81.6 Major histocompatibility complex class I deficiency
        • D81.7 Major histocompatibility complex class II deficiency
        • D81.8 Other combined immunodeficiencies
        • D81.81 Biotin-dependent carboxylase deficiency
        • D81.810 Biotinidase deficiency
        • D81.818 Other biotin-dependent carboxylase deficiency
        • D81.819 Biotin-dependent carboxylase deficiency, unspecified
        • D81.82 Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
        • D81.89 Other combined immunodeficiencies
        • D81.9 Combined immunodeficiency, unspecified
        • Immunodeficiency associated with other major defects (D82)

        • D82 Immunodeficiency associated with other major defects
        • D82.0 Wiskott-Aldrich syndrome
        • D82.1 Di George's syndrome
        • D82.2 Immunodeficiency with short-limbed stature
        • D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
        • D82.4 Hyperimmunoglobulin E [IgE] syndrome
        • D82.8 Immunodeficiency associated with other specified major defects
        • D82.9 Immunodeficiency associated with major defect, unspecified
        • Common variable immunodeficiency (D83)

        • D83 Common variable immunodeficiency
        • D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
        • D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
        • D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
        • D83.8 Other common variable immunodeficiencies
        • D83.9 Common variable immunodeficiency, unspecified
        • Other immunodeficiencies (D84)

        • D84 Other immunodeficiencies
        • D84.0 Lymphocyte function antigen-1 [LFA-1] defect
        • D84.1 Defects in the complement system
        • D84.8 Other specified immunodeficiencies
        • D84.81 Immunodeficiency due to conditions classified elsewhere
        • D84.82 Immunodeficiency due to drugs and external causes
        • D84.821 Immunodeficiency due to drugs
        • D84.822 Immunodeficiency due to external causes
        • D84.89 Other immunodeficiencies
        • D84.9 Immunodeficiency, unspecified
        • Sarcoidosis (D86)

        • D86 Sarcoidosis
        • D86.0 Sarcoidosis of lung
        • D86.1 Sarcoidosis of lymph nodes
        • D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
        • D86.3 Sarcoidosis of skin
        • D86.8 Sarcoidosis of other sites
        • D86.81 Sarcoid meningitis
        • D86.82 Multiple cranial nerve palsies in sarcoidosis
        • D86.83 Sarcoid iridocyclitis
        • D86.84 Sarcoid pyelonephritis
        • D86.85 Sarcoid myocarditis
        • D86.86 Sarcoid arthropathy
        • D86.87 Sarcoid myositis
        • D86.89 Sarcoidosis of other sites
        • D86.9 Sarcoidosis, unspecified
        • Other disorders involving the immune mechanism, not elsewhere classified (D89)

        • D89 Other disorders involving the immune mechanism, not elsewhere classified
        • D89.0 Polyclonal hypergammaglobulinemia
        • D89.1 Cryoglobulinemia
        • D89.2 Hypergammaglobulinemia, unspecified
        • D89.3 Immune reconstitution syndrome
        • D89.4 Mast cell activation syndrome and related disorders
        • D89.40 Mast cell activation, unspecified
        • D89.41 Monoclonal mast cell activation syndrome
        • D89.42 Idiopathic mast cell activation syndrome
        • D89.43 Secondary mast cell activation
        • D89.44 Hereditary alpha tryptasemia
        • D89.49 Other mast cell activation disorder
        • D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
        • D89.81 Graft-versus-host disease
        • D89.810 Acute graft-versus-host disease
        • D89.811 Chronic graft-versus-host disease
        • D89.812 Acute on chronic graft-versus-host disease
        • D89.813 Graft-versus-host disease, unspecified
        • D89.82 Autoimmune lymphoproliferative syndrome [ALPS]
        • D89.83 Cytokine release syndrome
        • D89.831 Cytokine release syndrome, grade 1
        • D89.832 Cytokine release syndrome, grade 2
        • D89.833 Cytokine release syndrome, grade 3
        • D89.834 Cytokine release syndrome, grade 4
        • D89.835 Cytokine release syndrome, grade 5
        • D89.839 Cytokine release syndrome, grade unspecified
        • D89.84 IgG4-related disease NEW CODE
        • D89.89 Other specified disorders involving the immune mechanism, not elsewhere classified
        • D89.9 Disorder involving the immune mechanism, unspecified