Abnormality of red blood cells (R71)
Clinical Information
Erythrocyte Aggregation - The formation of clumps of RED BLOOD CELLS under low or non-flow conditions, resulting from the attraction forces between the red blood cells. The cells adhere to each other in rouleaux aggregates. Slight mechanical force, such as occurs in the circulation, is enough to disperse these aggregates. Stronger or weaker than normal aggregation may result from a variety of effects in the ERYTHROCYTE MEMBRANE or in BLOOD PLASMA. The degree of aggregation is affected by ERYTHROCYTE DEFORMABILITY, erythrocyte membrane sialylation, masking of negative surface charge by plasma proteins, etc. BLOOD VISCOSITY and the ERYTHROCYTE SEDIMENTATION RATE are affected by the amount of erythrocyte aggregation and are parameters used to measure the aggregation.
Erythrocytes - Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.
Heinz Bodies - Abnormal intracellular inclusions, composed of denatured hemoglobin, found on the membrane of red blood cells. They are seen in thalassemias, enzymopathies, hemoglobinopathies, and after splenectomy.
HELLP Syndrome - A syndrome of HEMOLYSIS, elevated liver ENZYMES, and low blood platelets count (THROMBOCYTOPENIA). HELLP syndrome is observed in pregnant women with PRE-ECLAMPSIA or ECLAMPSIA who also exhibit LIVER damage and abnormalities in BLOOD COAGULATION.
Hemolysis - The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
Instructional Notations
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- anemias D50 D64
- anemia of premature infant P61.2
- benign familial polycythemia D75.0
- congenital anemias P61.2 P61.4
- newborn anemia due to isoimmunization P55
- polycythemia neonatorum P61.1
- polycythemia NOS D75.1
- polycythemia vera D45
- secondary polycythemia D75.1
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00–R99)
Abnormal findings on examination of blood, without diagnosis (R70-R79)
R71 Abnormality of red blood cells
- R71.0 Precipitous drop in hematocrit
- R71.8 Other abnormality of red blood cells
Abnormality of red blood cells (R71)